Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) relBE/RelE-RelB
Location 1869087..1869646 Replicon chromosome
Accession NZ_AP023054
Organism Thaumasiovibrio subtropicus strain C4V358

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag TSUB_RS08435 Protein ID WP_087025353.1
Coordinates 1869368..1869646 (+) Length 93 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag TSUB_RS08430 Protein ID WP_087025350.1
Coordinates 1869087..1869371 (+) Length 95 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
TSUB_RS08405 1864152..1864685 - 534 WP_221274507.1 hypothetical protein -
TSUB_RS08410 1865232..1866254 - 1023 WP_087025337.1 hypothetical protein -
TSUB_RS08415 1866500..1866772 - 273 WP_087025340.1 nicotinamide mononucleotide transporter -
TSUB_RS08420 1866935..1867708 - 774 WP_087025343.1 NERD domain-containing protein -
TSUB_RS08425 1868011..1868706 - 696 WP_087025346.1 SDR family NAD(P)-dependent oxidoreductase -
TSUB_RS08430 1869087..1869371 + 285 WP_087025350.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
TSUB_RS08435 1869368..1869646 + 279 WP_087025353.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
TSUB_RS08440 1869746..1870201 - 456 WP_087025356.1 macro domain-containing protein -
TSUB_RS08445 1870564..1870890 - 327 WP_087025360.1 DUF2834 domain-containing protein -
TSUB_RS08450 1871061..1871381 - 321 WP_087025363.1 hypothetical protein -
TSUB_RS08455 1871883..1872377 - 495 WP_246616337.1 hypothetical protein -
TSUB_RS25025 1872642..1872841 + 200 Protein_1647 IS110 family transposase -
TSUB_RS08460 1872885..1873187 - 303 WP_087025372.1 type II toxin-antitoxin system RelE/ParE family toxin -
TSUB_RS08465 1873175..1873432 - 258 WP_087025375.1 type II toxin-antitoxin system Phd/YefM family antitoxin -
TSUB_RS08470 1873790..1873990 + 201 Protein_1650 IS110 family transposase -
TSUB_RS08475 1874013..1874345 - 333 WP_087025378.1 hypothetical protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.



Sequences


Toxin        


Download         Length: 93 a.a.        Molecular weight: 10974.67 Da        Isoelectric Point: 4.5593

>T36687 WP_087025353.1 NZ_AP023054:1869368-1869646 [Thaumasiovibrio subtropicus]
MILWEEESLNDREKIFEFLYDFNPDAAEKTDNLIEAKVENLLEQPLMGVQRDSNRGRLLIIPEIAMIVSYWVEGDIIRIM
RVLHQKQKFPRN

Download         Length: 279 bp

>T36687 NZ_AP023054:1869368-1869646 [Thaumasiovibrio subtropicus]
ATGATTTTGTGGGAAGAAGAGTCACTCAATGATCGTGAAAAGATCTTCGAGTTTCTCTATGACTTCAACCCTGATGCGGC
AGAGAAAACTGACAATCTCATTGAAGCAAAAGTAGAAAACTTGCTTGAGCAACCTCTAATGGGAGTGCAACGAGATAGCA
ATCGCGGACGATTACTTATCATTCCTGAGATTGCGATGATCGTATCTTACTGGGTTGAAGGCGATATCATCCGTATTATG
CGTGTGCTCCACCAGAAACAGAAATTCCCTAGGAATTGA

Antitoxin


Download         Length: 95 a.a.        Molecular weight: 10992.35 Da        Isoelectric Point: 8.0500

>AT36687 WP_087025350.1 NZ_AP023054:1869087-1869371 [Thaumasiovibrio subtropicus]
MDTRIQFRVDEETKRLAQQMAESQGRTLSDACRELTEQLAEQQKKALSHDAWLTEQVNLAFEKLDSGKSVFIEHQTAKSR
MEERKARIRNRGKE

Download         Length: 285 bp

>AT36687 NZ_AP023054:1869087-1869371 [Thaumasiovibrio subtropicus]
ATGGACACTAGAATTCAATTTCGTGTTGATGAAGAAACAAAGCGCCTAGCTCAACAGATGGCTGAGAGCCAAGGTCGCAC
GCTAAGTGATGCTTGCCGTGAACTGACAGAGCAACTCGCAGAACAACAAAAAAAGGCACTATCTCACGATGCATGGCTAA
CTGAACAAGTAAACCTAGCATTTGAGAAGCTTGACTCAGGAAAATCCGTTTTCATTGAACACCAAACTGCGAAATCTCGA
ATGGAAGAGCGCAAAGCCAGAATCCGTAATCGAGGGAAGGAATGA

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Source ID Structure

References