Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | relBE/RelE-RelB |
Location | 1869087..1869646 | Replicon | chromosome |
Accession | NZ_AP023054 | ||
Organism | Thaumasiovibrio subtropicus strain C4V358 |
Toxin (Protein)
Gene name | relE | Uniprot ID | - |
Locus tag | TSUB_RS08435 | Protein ID | WP_087025353.1 |
Coordinates | 1869368..1869646 (+) | Length | 93 a.a. |
Antitoxin (Protein)
Gene name | relB | Uniprot ID | - |
Locus tag | TSUB_RS08430 | Protein ID | WP_087025350.1 |
Coordinates | 1869087..1869371 (+) | Length | 95 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
TSUB_RS08405 | 1864152..1864685 | - | 534 | WP_221274507.1 | hypothetical protein | - |
TSUB_RS08410 | 1865232..1866254 | - | 1023 | WP_087025337.1 | hypothetical protein | - |
TSUB_RS08415 | 1866500..1866772 | - | 273 | WP_087025340.1 | nicotinamide mononucleotide transporter | - |
TSUB_RS08420 | 1866935..1867708 | - | 774 | WP_087025343.1 | NERD domain-containing protein | - |
TSUB_RS08425 | 1868011..1868706 | - | 696 | WP_087025346.1 | SDR family NAD(P)-dependent oxidoreductase | - |
TSUB_RS08430 | 1869087..1869371 | + | 285 | WP_087025350.1 | type II toxin-antitoxin system RelB/DinJ family antitoxin | Antitoxin |
TSUB_RS08435 | 1869368..1869646 | + | 279 | WP_087025353.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
TSUB_RS08440 | 1869746..1870201 | - | 456 | WP_087025356.1 | macro domain-containing protein | - |
TSUB_RS08445 | 1870564..1870890 | - | 327 | WP_087025360.1 | DUF2834 domain-containing protein | - |
TSUB_RS08450 | 1871061..1871381 | - | 321 | WP_087025363.1 | hypothetical protein | - |
TSUB_RS08455 | 1871883..1872377 | - | 495 | WP_246616337.1 | hypothetical protein | - |
TSUB_RS25025 | 1872642..1872841 | + | 200 | Protein_1647 | IS110 family transposase | - |
TSUB_RS08460 | 1872885..1873187 | - | 303 | WP_087025372.1 | type II toxin-antitoxin system RelE/ParE family toxin | - |
TSUB_RS08465 | 1873175..1873432 | - | 258 | WP_087025375.1 | type II toxin-antitoxin system Phd/YefM family antitoxin | - |
TSUB_RS08470 | 1873790..1873990 | + | 201 | Protein_1650 | IS110 family transposase | - |
TSUB_RS08475 | 1874013..1874345 | - | 333 | WP_087025378.1 | hypothetical protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 93 a.a. Molecular weight: 10974.67 Da Isoelectric Point: 4.5593
>T36687 WP_087025353.1 NZ_AP023054:1869368-1869646 [Thaumasiovibrio subtropicus]
MILWEEESLNDREKIFEFLYDFNPDAAEKTDNLIEAKVENLLEQPLMGVQRDSNRGRLLIIPEIAMIVSYWVEGDIIRIM
RVLHQKQKFPRN
MILWEEESLNDREKIFEFLYDFNPDAAEKTDNLIEAKVENLLEQPLMGVQRDSNRGRLLIIPEIAMIVSYWVEGDIIRIM
RVLHQKQKFPRN
Download Length: 279 bp
>T36687 NZ_AP023054:1869368-1869646 [Thaumasiovibrio subtropicus]
ATGATTTTGTGGGAAGAAGAGTCACTCAATGATCGTGAAAAGATCTTCGAGTTTCTCTATGACTTCAACCCTGATGCGGC
AGAGAAAACTGACAATCTCATTGAAGCAAAAGTAGAAAACTTGCTTGAGCAACCTCTAATGGGAGTGCAACGAGATAGCA
ATCGCGGACGATTACTTATCATTCCTGAGATTGCGATGATCGTATCTTACTGGGTTGAAGGCGATATCATCCGTATTATG
CGTGTGCTCCACCAGAAACAGAAATTCCCTAGGAATTGA
ATGATTTTGTGGGAAGAAGAGTCACTCAATGATCGTGAAAAGATCTTCGAGTTTCTCTATGACTTCAACCCTGATGCGGC
AGAGAAAACTGACAATCTCATTGAAGCAAAAGTAGAAAACTTGCTTGAGCAACCTCTAATGGGAGTGCAACGAGATAGCA
ATCGCGGACGATTACTTATCATTCCTGAGATTGCGATGATCGTATCTTACTGGGTTGAAGGCGATATCATCCGTATTATG
CGTGTGCTCCACCAGAAACAGAAATTCCCTAGGAATTGA
Antitoxin
Download Length: 95 a.a. Molecular weight: 10992.35 Da Isoelectric Point: 8.0500
>AT36687 WP_087025350.1 NZ_AP023054:1869087-1869371 [Thaumasiovibrio subtropicus]
MDTRIQFRVDEETKRLAQQMAESQGRTLSDACRELTEQLAEQQKKALSHDAWLTEQVNLAFEKLDSGKSVFIEHQTAKSR
MEERKARIRNRGKE
MDTRIQFRVDEETKRLAQQMAESQGRTLSDACRELTEQLAEQQKKALSHDAWLTEQVNLAFEKLDSGKSVFIEHQTAKSR
MEERKARIRNRGKE
Download Length: 285 bp
>AT36687 NZ_AP023054:1869087-1869371 [Thaumasiovibrio subtropicus]
ATGGACACTAGAATTCAATTTCGTGTTGATGAAGAAACAAAGCGCCTAGCTCAACAGATGGCTGAGAGCCAAGGTCGCAC
GCTAAGTGATGCTTGCCGTGAACTGACAGAGCAACTCGCAGAACAACAAAAAAAGGCACTATCTCACGATGCATGGCTAA
CTGAACAAGTAAACCTAGCATTTGAGAAGCTTGACTCAGGAAAATCCGTTTTCATTGAACACCAAACTGCGAAATCTCGA
ATGGAAGAGCGCAAAGCCAGAATCCGTAATCGAGGGAAGGAATGA
ATGGACACTAGAATTCAATTTCGTGTTGATGAAGAAACAAAGCGCCTAGCTCAACAGATGGCTGAGAGCCAAGGTCGCAC
GCTAAGTGATGCTTGCCGTGAACTGACAGAGCAACTCGCAGAACAACAAAAAAAGGCACTATCTCACGATGCATGGCTAA
CTGAACAAGTAAACCTAGCATTTGAGAAGCTTGACTCAGGAAAATCCGTTTTCATTGAACACCAAACTGCGAAATCTCGA
ATGGAAGAGCGCAAAGCCAGAATCCGTAATCGAGGGAAGGAATGA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Structures
Toxin
Source | ID | Structure |
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Antitoxin
Source | ID | Structure |
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