Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) /SpoIISA(toxin)
Location 2389659..2390633 Replicon chromosome
Accession NZ_AP022956
Organism Bacillus cereus strain J51

Toxin (Protein)


Gene name spoIISA Uniprot ID -
Locus tag L6487_RS12290 Protein ID WP_062923173.1
Coordinates 2389659..2390396 (+) Length 246 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID -
Locus tag L6487_RS12295 Protein ID WP_062923165.1
Coordinates 2390508..2390633 (+) Length 42 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
L6487_RS12265 (BCJMU51_2384) 2385153..2385854 + 702 WP_236788434.1 hypothetical protein -
L6487_RS12270 (BCJMU51_2385) 2385982..2386866 + 885 WP_062923162.1 hypothetical protein -
L6487_RS12275 2387175..2387977 - 803 Protein_2341 thiamine pyrophosphate-binding protein -
L6487_RS12280 (BCJMU51_2388) 2388084..2388566 + 483 WP_062923163.1 MarR family winged helix-turn-helix transcriptional regulator -
L6487_RS12285 (BCJMU51_2389) 2388733..2389470 + 738 WP_062923164.1 2,3-diphosphoglycerate-dependent phosphoglycerate mutase -
L6487_RS12290 (BCJMU51_2390) 2389659..2390396 + 738 WP_062923173.1 type II toxin-antitoxin system SpoIISA family toxin Toxin
L6487_RS12295 (BCJMU51_2391) 2390508..2390633 + 126 WP_062923165.1 hypothetical protein Antitoxin
L6487_RS12300 (BCJMU51_2392) 2390708..2390884 + 177 WP_062923166.1 stage II sporulation protein SB -
L6487_RS12305 (BCJMU51_2393) 2390903..2391292 - 390 WP_062923167.1 YxeA family protein -
L6487_RS12310 (BCJMU51_2394) 2391509..2392978 + 1470 WP_062923168.1 beta-Ala-His dipeptidase -
L6487_RS12315 (BCJMU51_2395) 2393018..2393167 - 150 WP_236809090.1 hypothetical protein -
L6487_RS12320 (BCJMU51_2396) 2393559..2394029 - 471 WP_061530815.1 DUF5065 family protein -
L6487_RS12325 (BCJMU51_2397) 2394483..2395142 + 660 WP_000876955.1 CatB-related O-acetyltransferase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin SpoIISA, type II toxin-antitoxin system

(9-243)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 246 a.a.        Molecular weight: 28351.03 Da        Isoelectric Point: 8.3034

>T36653 WP_062923173.1 NZ_AP022956:2389659-2390396 [Bacillus cereus]
VISNIRIGLFILAIVFLVLVFFYWRNEELYEEKKQRIRKTWYGLFIVSVTVYFMIKGIDLTLWKNLLMFTAMVIFVDIAF
ILTPNISEIWGAKFSDIGKTVQSIKRSLIASKARGEIYTTIIQNVNPAVFGTMEWHTEEEYIKSLNAFLDSYGEKIGAKI
VVFEAAKELNTNFRGIRSQFSIIVPFEHIEQLNEQKAVQVENVGIIPAKTVSDVFIVIDGKKNNLQDRDFENVYNLTIHH
SYFSK

Download         Length: 738 bp

>T36653 NZ_AP022956:2389659-2390396 [Bacillus cereus]
GTGATCTCTAACATTCGAATCGGTTTATTTATTTTAGCAATCGTTTTTCTAGTTCTTGTTTTCTTTTACTGGAGAAATGA
AGAGTTGTACGAAGAGAAGAAGCAACGGATTAGAAAGACTTGGTATGGGTTGTTTATAGTATCAGTCACCGTGTATTTCA
TGATAAAAGGAATTGATTTAACCCTCTGGAAAAATCTTTTAATGTTCACTGCAATGGTTATTTTCGTTGATATTGCATTT
ATTTTAACACCTAATATTTCAGAAATATGGGGAGCGAAATTTAGCGATATCGGCAAGACTGTTCAATCGATAAAACGGTC
ATTAATTGCTTCTAAAGCAAGAGGAGAAATATACACAACAATTATTCAAAATGTCAATCCGGCAGTATTCGGTACGATGG
AATGGCATACGGAAGAAGAATATATAAAAAGCTTAAACGCATTTTTAGATTCGTATGGTGAAAAGATTGGGGCAAAAATT
GTTGTATTTGAAGCGGCAAAGGAATTAAATACAAACTTTCGCGGTATCCGCTCACAATTTAGTATCATCGTTCCGTTTGA
ACATATTGAGCAATTGAATGAGCAGAAAGCGGTGCAAGTAGAAAATGTCGGAATTATACCGGCAAAAACTGTGAGTGATG
TTTTCATTGTTATTGATGGGAAGAAAAATAATCTGCAAGATCGAGATTTTGAAAATGTATATAATTTAACAATACATCAT
AGTTATTTTAGTAAATAA

Antitoxin


Download         Length: 42 a.a.        Molecular weight: 4938.34 Da        Isoelectric Point: 3.9150

>AT36653 WP_062923165.1 NZ_AP022956:2390508-2390633 [Bacillus cereus]
VIKDYDNDFFKEENEDTTDFSLIKGDTLQQVEELEDELKRK

Download         Length: 126 bp

>AT36653 NZ_AP022956:2390508-2390633 [Bacillus cereus]
GTGATAAAAGATTATGACAATGATTTTTTTAAAGAAGAAAATGAAGATACAACAGATTTCTCGTTAATAAAAGGAGATAC
ATTACAGCAAGTAGAAGAATTAGAAGATGAATTAAAAAGAAAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References