Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relE-yefM/YoeB-RelB
Location 4196978..4197507 Replicon chromosome
Accession NZ_AP022871
Organism Phytohabitans suffuscus strain NBRC 105367

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag Psuf_RS18255 Protein ID WP_173158326.1
Coordinates 4197250..4197507 (+) Length 86 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag Psuf_RS18250 Protein ID WP_173158325.1
Coordinates 4196978..4197253 (+) Length 92 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
Psuf_RS18235 4193401..4195811 + 2411 Protein_3653 DEAD/DEAH box helicase -
Psuf_RS18240 4196249..4196458 + 210 WP_173158324.1 type II toxin-antitoxin system VapB family antitoxin -
Psuf_RS18245 4196461..4196892 + 432 WP_197946430.1 PIN domain-containing protein -
Psuf_RS18250 4196978..4197253 + 276 WP_173158325.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
Psuf_RS18255 4197250..4197507 + 258 WP_173158326.1 Txe/YoeB family addiction module toxin Toxin
Psuf_RS45290 4197559..4198173 + 615 WP_197945934.1 hypothetical protein -
Psuf_RS18265 4198184..4199335 + 1152 WP_173158327.1 helix-turn-helix domain-containing protein -
Psuf_RS18270 4199902..4200105 - 204 WP_173158328.1 hypothetical protein -
Psuf_RS18275 4200454..4200711 + 258 WP_173166602.1 DUF397 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(2-82)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-74)


Sequences

Toxin        


Download         Length: 86 a.a.        Molecular weight: 10090.49 Da        Isoelectric Point: 8.8985

>T36625 WP_173158326.1 NZ_AP022871:4197250-4197507 [Phytohabitans suffuscus]
VRLVFTPTAWEQYLSHTDRKLVKRINDLIADVMRNGYEGIGKPEPLRGELSGFWSRRIDREHRLVYRITEGDIEIAACRY
HYADR

Download         Length: 258 bp

>T36625 NZ_AP022871:4197250-4197507 [Phytohabitans suffuscus]
GTGAGGCTGGTCTTCACGCCTACCGCGTGGGAGCAGTACCTCAGTCACACCGACCGCAAGCTGGTCAAGCGGATCAACGA
CCTTATCGCGGATGTCATGCGCAACGGCTACGAGGGCATCGGTAAGCCGGAGCCGCTTCGCGGAGAACTATCAGGCTTCT
GGTCCAGACGTATCGATCGCGAACACCGGCTGGTGTACCGGATCACCGAGGGCGACATCGAGATCGCCGCTTGTCGATAC
CACTACGCCGACAGGTAG

Antitoxin


Download         Length: 92 a.a.        Molecular weight: 10165.40 Da        Isoelectric Point: 4.3356

>AT36625 WP_173158325.1 NZ_AP022871:4196978-4197253 [Phytohabitans suffuscus]
MRTVNFTQLRQNLAAELDSVINDAEEVVVTRSGHEPVVIVPLAEYEAMKETEYLLRNPSNAAALRRSIAELERGEAGERE
LIDPTTIRDTA

Download         Length: 276 bp

>AT36625 NZ_AP022871:4196978-4197253 [Phytohabitans suffuscus]
ATGCGAACCGTCAACTTCACCCAACTACGGCAGAACCTCGCCGCTGAGCTGGACAGCGTGATCAACGATGCGGAGGAAGT
GGTGGTGACCAGGTCGGGCCACGAGCCGGTGGTCATCGTGCCGCTCGCGGAGTACGAGGCGATGAAGGAGACGGAGTACC
TGCTTCGTAACCCGAGCAACGCCGCAGCTCTGCGCCGGTCCATCGCGGAACTGGAACGCGGTGAAGCCGGCGAGCGAGAG
CTCATCGATCCCACCACCATCCGGGACACTGCGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References