Detailed information of TA system TA036619

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): vapBC/VapC(toxin)
• Location: 389812..390476
• Replicon: chromosome
• Accession: NZ_AP022870
• Organism: Phytohabitans flavus strain NBRC 107702

Toxin (Protein)

• Gene name: vapC
• Uniprot ID: -
• Locus tag: Pflav_RS01745
• Protein ID: WP_173033194.1
• Coordinates: 389812..390207 (-)
• Length: 132 a.a.

Antitoxin (Protein)

• Gene name: vapB
• Uniprot ID: -
• Locus tag: Pflav_RS01750
• Protein ID: WP_173033195.1
• Coordinates: 390204..390476 (-)
• Length: 91 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
Pflav_RS01740	388335..389810	+	1476	WP_173033193.1	glutamate synthase subunit beta	-
Pflav_RS01745	389812..390207	-	396	WP_173033194.1	type II toxin-antitoxin system VapC family toxin	Toxin
Pflav_RS01750	390204..390476	-	273	WP_173033195.1	type II toxin-antitoxin system VapB family antitoxin	Antitoxin
Pflav_RS01755	390554..391621	-	1068	WP_173033196.1	hypothetical protein	-
Pflav_RS01760	391785..392084	+	300	WP_173033197.1	hypothetical protein	-
Pflav_RS01765	392081..393676	+	1596	WP_173033199.1	amidase	-
Pflav_RS01770	393830..395368	-	1539	WP_173033201.1	phosphoenolpyruvate--protein phosphotransferase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• PIN domain (1-125)

Antitoxin

• Antitoxin VapB-like (1-89)

Sequences

Toxin

Protein

• Length: 132 a.a.
• Molecular weight: 13925.07 Da
• Isoelectric Point: 4.6135

>T36619 WP_173033194.1 NZ_AP022870:c390207-389812 [Phytohabitans flavus]
VIVDSSAIVAILLQEPGWEPLLDRLVGSEDPAGVGAPTLVETGIVLAARLGIPGKTLLARFIQESSLRVISFTADHWPVA
VDAYLRYGKGRHPAALNFGDCLTYAVGRVASEPLLCLGNDFARTDLSLVEV

Nucleotide

• Length: 396 bp

>T36619 NZ_AP022870:c390207-389812 [Phytohabitans flavus]
GTGATCGTCGACAGCTCGGCGATCGTCGCGATCCTGCTCCAAGAGCCGGGCTGGGAGCCGCTACTGGACCGACTCGTGGG
GTCGGAGGATCCGGCCGGTGTAGGGGCCCCGACCCTCGTGGAGACCGGCATCGTGCTGGCAGCCCGGCTCGGCATTCCCG
GAAAGACCCTGCTCGCACGGTTCATCCAAGAGAGTTCGCTGCGGGTCATCTCGTTCACCGCGGACCACTGGCCCGTGGCC
GTCGACGCCTACCTGCGGTACGGCAAGGGTCGCCACCCCGCCGCATTGAACTTCGGCGACTGCCTCACGTACGCGGTCGG
CCGCGTCGCGAGCGAGCCATTGCTCTGCCTTGGCAATGACTTCGCTCGGACGGACCTCTCGCTCGTCGAGGTCTGA

Antitoxin

Protein

• Length: 91 a.a.
• Molecular weight: 9819.12 Da
• Isoelectric Point: 6.3846

>AT36619 WP_173033195.1 NZ_AP022870:c390476-390204 [Phytohabitans flavus]
MALNVKDPETEQLAAEVAALAGESKTRAINVALRERRARLMAAGAARDRGARLRRFLTDEAWPQVPDEVRGTALTKAERE
EILGYGSEGV

Nucleotide

• Length: 273 bp

>AT36619 NZ_AP022870:c390476-390204 [Phytohabitans flavus]
ATGGCACTGAACGTGAAGGACCCGGAGACCGAGCAGCTCGCGGCCGAGGTGGCCGCGCTCGCCGGGGAAAGCAAGACCCG
GGCGATCAACGTCGCCCTGAGGGAGCGCCGCGCCCGTCTGATGGCGGCAGGCGCCGCACGCGATCGCGGCGCACGCCTTC
GCCGTTTCCTCACGGACGAGGCGTGGCCACAGGTGCCCGACGAGGTACGCGGCACCGCGCTGACGAAGGCCGAGCGCGAG
GAGATCCTGGGCTACGGGTCGGAGGGCGTGTGA