36590

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/LOTUS_5_Limkain_b1-Phd
Location 840666..841327 Replicon chromosome
Accession NZ_AP022853
Organism Sulfurimicrobium lacus strain skT11

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag SKTS_RS04290 Protein ID WP_173060829.1
Coordinates 840666..841079 (-) Length 138 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag SKTS_RS04295 Protein ID WP_173060832.1
Coordinates 841076..841327 (-) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
SKTS_RS04270 836343..836873 - 531 WP_173060817.1 hypothetical protein -
SKTS_RS04275 836860..837675 - 816 WP_173060820.1 archaeosortase/exosortase family protein -
SKTS_RS04280 837876..839885 - 2010 WP_173060823.1 VIT and VWA domain-containing protein -
SKTS_RS04285 839919..840494 - 576 WP_173060826.1 metal-dependent hydrolase -
SKTS_RS04290 840666..841079 - 414 WP_173060829.1 type II toxin-antitoxin system VapC family toxin Toxin
SKTS_RS04295 841076..841327 - 252 WP_173060832.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
SKTS_RS04300 841417..841911 - 495 WP_173060834.1 PH domain-containing protein -
SKTS_RS04305 842056..842640 - 585 WP_173068909.1 DsrE/DsrF/DrsH-like family protein -
SKTS_RS04310 842696..842923 - 228 WP_173060837.1 sulfurtransferase TusA family protein -
SKTS_RS04315 843027..843629 - 603 WP_173060840.1 TetR/AcrR family transcriptional regulator -
SKTS_RS04320 843944..845512 + 1569 WP_173060843.1 diguanylate cyclase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(3-126)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-57)


Sequences

Toxin        


Download         Length: 138 a.a.        Molecular weight: 15218.61 Da        Isoelectric Point: 5.8684

>T36590 WP_173060829.1 NZ_AP022853:c841079-840666 [Sulfurimicrobium lacus]
MSYLVDTNVLSELRRKNPNPGVVTWFTQRPATTLYLSVLTLGEIRKGIEGLGDEKRRMALLDWLETDLPAFFTGRILPVD
APVADRWGRLVAAAGRPLPAIDSLLAATALVHDLVLVTRNSRDFSDLPVQLINPWAE

Download         Length: 414 bp

>T36590 NZ_AP022853:c841079-840666 [Sulfurimicrobium lacus]
TTGAGCTACCTCGTCGATACCAACGTGCTATCGGAATTGCGGCGCAAGAACCCAAACCCCGGCGTCGTAACCTGGTTCAC
GCAACGCCCCGCCACCACCTTGTACCTGAGCGTCCTCACGCTGGGTGAGATACGCAAAGGCATCGAAGGTCTGGGCGACG
AAAAGCGGCGCATGGCTTTGCTGGACTGGCTGGAAACAGACCTGCCCGCCTTCTTTACCGGAAGAATCCTCCCCGTTGAC
GCCCCCGTCGCGGACCGCTGGGGACGGCTGGTAGCAGCGGCCGGGCGCCCCTTGCCCGCGATTGACAGTCTGCTGGCGGC
GACCGCGCTAGTGCACGATCTGGTTCTGGTAACGCGAAATAGCCGAGATTTCAGCGATCTTCCGGTTCAGTTGATCAATC
CTTGGGCGGAATGA

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9578.88 Da        Isoelectric Point: 5.5514

>AT36590 WP_173060832.1 NZ_AP022853:c841327-841076 [Sulfurimicrobium lacus]
MHSWQIQEAKARISEVVKCAQNQGPQEITLHGKPVAVLVSCETYDRLAHRSDSLLEFMHRSPLYGLEEIEFVRDQSLTRE
VEL

Download         Length: 252 bp

>AT36590 NZ_AP022853:c841327-841076 [Sulfurimicrobium lacus]
ATGCACTCATGGCAAATACAGGAAGCGAAGGCGCGCATCTCGGAAGTCGTCAAATGCGCACAGAATCAGGGGCCGCAGGA
AATTACGCTGCACGGCAAGCCCGTCGCGGTCCTGGTCTCCTGTGAGACCTATGACCGGCTAGCCCACAGGAGCGATTCCC
TGCTCGAATTCATGCACCGCTCGCCCTTGTACGGACTTGAAGAAATCGAATTCGTGCGCGACCAGAGCCTCACCCGCGAG
GTTGAGCTTTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References