Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumAB/COG3657-dnstrm_HI1420
Location 3925847..3926445 Replicon chromosome
Accession NZ_AP022850
Organism Halomonas sp. A020

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag FRH_RS18450 Protein ID WP_239296521.1
Coordinates 3925847..3926146 (+) Length 100 a.a.

Antitoxin (Protein)


Gene name PumB Uniprot ID -
Locus tag FRH_RS18455 Protein ID WP_044630743.1
Coordinates 3926143..3926445 (+) Length 101 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FRH_RS18435 (HaloA020_36450) 3921646..3924204 - 2559 WP_281997495.1 ABC transporter permease -
FRH_RS18440 (HaloA020_36460) 3924197..3925012 - 816 WP_139526950.1 ABC transporter ATP-binding protein -
FRH_RS18445 (HaloA020_36470) 3925218..3925763 + 546 WP_281998182.1 arylesterase -
FRH_RS18450 (HaloA020_36480) 3925847..3926146 + 300 WP_239296521.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
FRH_RS18455 (HaloA020_36490) 3926143..3926445 + 303 WP_044630743.1 putative addiction module antidote protein Antitoxin
FRH_RS18460 (HaloA020_36500) 3926525..3927238 + 714 WP_153842730.1 transglutaminase-like cysteine peptidase -
FRH_RS18465 (HaloA020_36510) 3927252..3929159 + 1908 WP_153842729.1 EAL domain-containing protein -
FRH_RS18470 (HaloA020_36520) 3929215..3929538 - 324 WP_139526945.1 tryptophan synthase subunit beta like protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(1-95)

Antitoxin

Uncharacterized protein HI1420

(5-91)


Sequences

Toxin        


Download         Length: 100 a.a.        Molecular weight: 11236.84 Da        Isoelectric Point: 10.4476

>T36589 WP_239296521.1 NZ_AP022850:3925847-3926146 [Halomonas sp. A020]
MIAIKQTDTYRRWERKLRDSRAKALIAARIFRLANGLAGDVKPVGQGISELRIHHGPGYRVYFKQRGNELVILLCGGDKS
TQQNDIDTAQRLAAQWEES

Download         Length: 300 bp

>T36589 NZ_AP022850:3925847-3926146 [Halomonas sp. A020]
ATGATTGCTATTAAACAGACCGACACTTACCGACGGTGGGAACGTAAGCTCCGTGATTCGCGCGCAAAAGCACTGATTGC
TGCTCGTATTTTCAGGCTAGCCAACGGATTAGCTGGCGATGTAAAACCCGTTGGCCAAGGCATCAGTGAACTGCGTATTC
ATCATGGCCCAGGATATCGTGTCTATTTTAAACAACGCGGTAACGAACTTGTCATCCTTTTATGTGGTGGCGATAAAAGC
ACGCAGCAAAACGATATCGATACAGCGCAGCGTCTGGCAGCACAATGGGAGGAATCATGA

Antitoxin


Download         Length: 101 a.a.        Molecular weight: 10927.48 Da        Isoelectric Point: 4.3766

>AT36589 WP_044630743.1 NZ_AP022850:3926143-3926445 [Halomonas sp. A020]
MSDKIYDYDPAAALENDEAIALFLADALETGDATYVAKAMGIVARAKGMTELARETGLSREQLYRSFSEQGNPTLKTMLA
VMRALGMDLTAKPHQEEPVM

Download         Length: 303 bp

>AT36589 NZ_AP022850:3926143-3926445 [Halomonas sp. A020]
ATGAGCGATAAGATTTACGACTATGACCCGGCAGCAGCATTAGAGAACGATGAAGCCATCGCTCTCTTTCTCGCTGATGC
CCTGGAAACCGGAGATGCCACTTATGTTGCTAAAGCGATGGGTATCGTAGCGCGCGCTAAGGGAATGACAGAACTTGCTC
GCGAAACTGGCCTCTCCCGTGAACAGCTCTATCGTTCGTTCAGCGAGCAAGGCAACCCAACGCTGAAGACGATGTTAGCT
GTCATGCGTGCACTGGGTATGGACTTAACGGCAAAACCACACCAAGAAGAACCCGTCATGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References