Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YoeB-YefM
Location 2270616..2271118 Replicon chromosome
Accession NZ_AP022850
Organism Halomonas sp. A020

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag FRH_RS10510 Protein ID WP_281996847.1
Coordinates 2270616..2270870 (-) Length 85 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag FRH_RS10515 Protein ID WP_081195530.1
Coordinates 2270867..2271118 (-) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FRH_RS10485 (HaloA020_20870) 2266832..2267500 - 669 WP_281996842.1 thiaminase II -
FRH_RS10490 (HaloA020_20880) 2268121..2268606 + 486 WP_281996843.1 hypothetical protein -
FRH_RS10495 (HaloA020_20890) 2268608..2269195 + 588 WP_281996844.1 ImmA/IrrE family metallo-endopeptidase -
FRH_RS10500 (HaloA020_20900) 2269309..2269509 + 201 WP_281996845.1 hypothetical protein -
FRH_RS10505 (HaloA020_20920) 2269964..2270305 + 342 WP_281996846.1 hypothetical protein -
FRH_RS10510 (HaloA020_20940) 2270616..2270870 - 255 WP_281996847.1 Txe/YoeB family addiction module toxin Toxin
FRH_RS10515 (HaloA020_20950) 2270867..2271118 - 252 WP_081195530.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
FRH_RS10520 (HaloA020_20960) 2271282..2272103 - 822 WP_281996848.1 aldo/keto reductase -
FRH_RS10525 (HaloA020_20970) 2272299..2272763 + 465 WP_281996849.1 OsmC family protein -
FRH_RS10530 (HaloA020_20980) 2272844..2273272 + 429 WP_281996850.1 GFA family protein -
FRH_RS10535 (HaloA020_20990) 2273275..2273733 + 459 WP_281996851.1 N-acetyltransferase -
FRH_RS10540 (HaloA020_21000) 2273868..2275274 + 1407 WP_281996852.1 ATP-binding protein -
FRH_RS10545 (HaloA020_21010) 2275317..2275712 + 396 WP_219863089.1 response regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-74)


Sequences

Toxin        


Download         Length: 85 a.a.        Molecular weight: 10203.84 Da        Isoelectric Point: 9.9936

>T36588 WP_281996847.1 NZ_AP022850:c2270870-2270616 [Halomonas sp. A020]
MKLIFSENAWEDYLYWQKTDKKVLNRINKLIKEIKRAPFEGVGKPEPLKHNLAGYWSRRINEEHRIVYKVTDDALLIAQL
RYHY

Download         Length: 255 bp

>T36588 NZ_AP022850:c2270870-2270616 [Halomonas sp. A020]
ATGAAGCTCATCTTTTCCGAGAACGCCTGGGAGGACTATTTGTACTGGCAGAAAACCGATAAGAAGGTTCTTAACCGAAT
CAACAAGCTAATCAAAGAAATCAAGCGAGCGCCATTTGAAGGAGTTGGCAAGCCAGAACCCCTTAAACATAACCTCGCGG
GTTACTGGTCTCGGCGAATCAACGAAGAACACCGCATCGTTTACAAGGTCACGGACGACGCTTTGCTTATTGCCCAGCTG
CGGTATCACTACTGA

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9312.58 Da        Isoelectric Point: 4.4750

>AT36588 WP_081195530.1 NZ_AP022850:c2271118-2270867 [Halomonas sp. A020]
MDAISYTAARTNLAKTMEQVCEDHSPMIITRNKAQSVVMISLEDYEALQETAYLLRAPKNARRLLESVAELEQGGGQEKE
LLE

Download         Length: 252 bp

>AT36588 NZ_AP022850:c2271118-2270867 [Halomonas sp. A020]
ATGGATGCCATCAGCTACACCGCCGCTAGAACCAACCTAGCAAAAACCATGGAGCAGGTTTGTGAAGACCACTCTCCTAT
GATCATCACCCGCAATAAGGCGCAATCCGTGGTCATGATCTCTCTCGAAGACTATGAAGCACTGCAAGAGACAGCCTACC
TCCTGCGCGCACCCAAGAACGCCCGCCGTTTACTGGAATCCGTTGCCGAGTTGGAGCAAGGGGGCGGTCAGGAAAAGGAG
CTTCTTGAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References