Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumA-relB/upstrm_HI1419-dnstrm_HI1420
Location 2423286..2423859 Replicon chromosome
Accession NZ_AP022848
Organism Bosea sp. ANAM02

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag OCUBac02_RS11670 Protein ID WP_173049516.1
Coordinates 2423286..2423576 (+) Length 97 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag OCUBac02_RS11675 Protein ID WP_173045790.1
Coordinates 2423578..2423859 (+) Length 94 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OCUBac02_RS11655 2418673..2420529 + 1857 WP_173045786.1 TRAP transporter large permease subunit -
OCUBac02_RS11660 2420598..2421872 + 1275 WP_047582666.1 nicotinate phosphoribosyltransferase -
OCUBac02_RS11665 2421972..2423162 + 1191 WP_173045788.1 elongation factor Tu -
OCUBac02_RS11670 2423286..2423576 + 291 WP_173049516.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
OCUBac02_RS11675 2423578..2423859 + 282 WP_173045790.1 putative addiction module antidote protein Antitoxin
OCUBac02_RS11680 2423965..2424864 + 900 WP_173045792.1 dihydrodipicolinate synthase family protein -
OCUBac02_RS11690 2425057..2425788 + 732 WP_173045793.1 class I SAM-dependent methyltransferase -
OCUBac02_RS11695 2425949..2426143 + 195 WP_047577925.1 preprotein translocase subunit SecE -
OCUBac02_RS11700 2426158..2426691 + 534 WP_047577926.1 transcription termination/antitermination protein NusG -
OCUBac02_RS11705 2426902..2427333 + 432 WP_047577922.1 50S ribosomal protein L11 -
OCUBac02_RS11710 2427347..2428045 + 699 WP_047577919.1 50S ribosomal protein L1 -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(13-92)

Antitoxin

Uncharacterized protein HI1420

(4-91)


Sequences

Toxin        


Download         Length: 97 a.a.        Molecular weight: 10785.48 Da        Isoelectric Point: 10.6073

>T36586 WP_173049516.1 NZ_AP022848:2423286-2423576 [Bosea sp. ANAM02]
VFEVRQTTAFSCWLSGLRDVRAQLRIAARIRRLEEGNAGDVKSVGQGVSEMRIDYGPGYRLYFVRQGRTLVILLCGGDKR
TQPADIAKARQMAKEL

Download         Length: 291 bp

>T36586 NZ_AP022848:2423286-2423576 [Bosea sp. ANAM02]
GTGTTCGAAGTCCGGCAAACGACGGCTTTTTCCTGCTGGCTCAGCGGCCTTCGCGACGTCCGCGCTCAGCTTCGGATCGC
TGCGCGCATTCGGCGACTTGAGGAAGGTAACGCTGGCGACGTGAAGTCCGTTGGCCAAGGCGTCAGCGAAATGCGGATCG
ACTACGGGCCCGGTTATCGACTGTATTTCGTCCGGCAAGGCAGGACGCTGGTGATCCTGTTGTGCGGGGGCGACAAGCGG
ACTCAACCGGCGGATATCGCCAAAGCAAGGCAGATGGCGAAGGAGCTGTGA

Antitoxin


Download         Length: 94 a.a.        Molecular weight: 10209.63 Da        Isoelectric Point: 4.7719

>AT36586 WP_173045790.1 NZ_AP022848:2423578-2423859 [Bosea sp. ANAM02]
MPLETTKFDIQDYLKTFEQQAAYIEAALEENDPAFLAKALGDVARARGMTQVARDAGVTREALYRALSETGDPRLSTFLG
VLNSLGFKLRIAA

Download         Length: 282 bp

>AT36586 NZ_AP022848:2423578-2423859 [Bosea sp. ANAM02]
ATGCCTCTCGAAACCACCAAGTTCGACATCCAGGACTATCTCAAGACGTTCGAACAGCAGGCCGCCTATATCGAGGCGGC
GCTTGAGGAGAATGACCCGGCTTTCCTGGCGAAGGCGCTCGGGGATGTCGCCCGGGCGCGGGGCATGACGCAGGTCGCTA
GGGATGCAGGCGTGACCCGCGAAGCGCTGTACCGGGCTCTCAGCGAGACGGGCGATCCACGTCTGTCCACCTTCCTGGGG
GTGCTCAACTCCCTGGGATTTAAGCTGAGGATCGCCGCCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References