Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) stbE-relB/ParE-YafN
Location 2152792..2153308 Replicon chromosome
Accession NZ_AP022848
Organism Bosea sp. ANAM02

Toxin (Protein)


Gene name stbE Uniprot ID -
Locus tag OCUBac02_RS10340 Protein ID WP_173045412.1
Coordinates 2152792..2153073 (-) Length 94 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag OCUBac02_RS10345 Protein ID WP_173045414.1
Coordinates 2153063..2153308 (-) Length 82 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OCUBac02_RS10305 2147881..2148636 - 756 WP_047578237.1 flagellar type III secretion system protein FliR -
OCUBac02_RS10310 2148714..2148980 - 267 WP_047578234.1 flagellar biosynthesis protein FliQ -
OCUBac02_RS10315 2149131..2149454 - 324 WP_047578239.1 flagellar hook-basal body complex protein FliE -
OCUBac02_RS10320 2149484..2149894 - 411 WP_047578241.1 flagellar basal body rod protein FlgC -
OCUBac02_RS10325 2149912..2150313 - 402 WP_047578244.1 flagellar basal body rod protein FlgB -
OCUBac02_RS10330 2150537..2151856 + 1320 WP_173045410.1 flagellar biosynthetic protein FliO -
OCUBac02_RS10335 2152021..2152779 + 759 WP_173049483.1 flagellar type III secretion system pore protein FliP -
OCUBac02_RS10340 2152792..2153073 - 282 WP_173045412.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
OCUBac02_RS10345 2153063..2153308 - 246 WP_173045414.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
OCUBac02_RS10350 2153402..2154541 - 1140 WP_173045416.1 ribonuclease D -
OCUBac02_RS10355 2154684..2156462 + 1779 WP_173049485.1 aspartate--tRNA ligase -
OCUBac02_RS10360 2156468..2156836 + 369 WP_047576184.1 hypothetical protein -
OCUBac02_RS10365 2156852..2157154 + 303 WP_173045418.1 hypothetical protein -
OCUBac02_RS10370 2157197..2158078 + 882 WP_173045420.1 glycosyltransferase family 2 protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-83)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(8-77)


Sequences

Toxin        


Download         Length: 94 a.a.        Molecular weight: 10905.80 Da        Isoelectric Point: 10.9316

>T36585 WP_173045412.1 NZ_AP022848:c2153073-2152792 [Bosea sp. ANAM02]
MSYRLEFLPSARKEWDKLGATLREQFKKKLGERLTHPRVIADALHGLPDHYKIKLRAAGYRLVYRVEDERITVIVVGVGK
RKRSQVYEAAKKR

Download         Length: 282 bp

>T36585 NZ_AP022848:c2153073-2152792 [Bosea sp. ANAM02]
ATGAGCTATAGGCTCGAGTTCCTGCCATCGGCGCGGAAGGAATGGGACAAGCTCGGCGCAACGCTGCGCGAGCAGTTCAA
GAAGAAGCTCGGCGAGCGGCTGACCCACCCGAGAGTCATCGCCGATGCGCTGCACGGCCTGCCCGATCACTACAAGATCA
AGCTCCGCGCAGCGGGCTACCGATTGGTCTATCGCGTCGAGGACGAGCGGATCACGGTGATCGTCGTGGGGGTGGGCAAG
CGCAAACGCTCTCAGGTCTATGAAGCCGCGAAGAAGCGGTGA

Antitoxin


Download         Length: 82 a.a.        Molecular weight: 8816.12 Da        Isoelectric Point: 4.5388

>AT36585 WP_173045414.1 NZ_AP022848:c2153308-2153063 [Bosea sp. ANAM02]
MQRVEAEIAVSVSDLKKNPTAVVDGARGNPVAILNHNRVMAYMVPADTYEALVDALDDQLLVEIIRARATEKGKPVSLDE
L

Download         Length: 246 bp

>AT36585 NZ_AP022848:c2153308-2153063 [Bosea sp. ANAM02]
ATGCAGCGTGTCGAAGCCGAAATCGCCGTCAGCGTCTCCGATCTCAAGAAGAATCCCACCGCCGTCGTCGATGGCGCGCG
AGGCAACCCTGTCGCGATCCTCAACCACAATCGCGTCATGGCCTATATGGTGCCGGCCGATACCTATGAAGCGCTGGTGG
ACGCGCTAGACGACCAGCTTCTCGTCGAGATCATCCGGGCGCGAGCCACCGAAAAGGGCAAGCCGGTCAGCCTCGATGAG
CTATAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References