Detailed information of TA system TA036583

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): PP_4151-4152/excise(antitoxin)
• Location: 226471..227482
• Replicon: chromosome
• Accession: NZ_AP022848
• Organism: Bosea sp. ANAM02

Toxin (Protein)

• Gene name: PP_4152
• Uniprot ID: -
• Locus tag: OCUBac02_RS01110
• Protein ID: WP_173049218.1
• Coordinates: 226907..227482 (+)
• Length: 192 a.a.

Antitoxin (Protein)

• Gene name: PP_4151
• Uniprot ID: -
• Locus tag: OCUBac02_RS01105
• Protein ID: WP_173043133.1
• Coordinates: 226471..226911 (+)
• Length: 147 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
OCUBac02_RS01090	222451..223578	+	1128	WP_173049216.1	helicase RepA family protein	-
OCUBac02_RS01095	224048..224500	+	453	WP_173043131.1	hypothetical protein	-
OCUBac02_RS01100	224497..226368	+	1872	WP_173043132.1	phage terminase large subunit family protein	-
OCUBac02_RS01105	226471..226911	+	441	WP_173043133.1	helix-turn-helix domain-containing protein	Antitoxin
OCUBac02_RS01110	226907..227482	+	576	WP_173049218.1	PIN domain-containing protein	Toxin
OCUBac02_RS01115	227764..227964	+	201	WP_173043134.1	hypothetical protein	-
OCUBac02_RS01120	228121..228792	+	672	WP_173043135.1	hypothetical protein	-
OCUBac02_RS01125	228856..229071	-	216	WP_173049220.1	helix-turn-helix transcriptional regulator	-
OCUBac02_RS01130	229157..229675	+	519	WP_173043136.1	hypothetical protein	-
OCUBac02_RS01135	229665..230255	+	591	WP_173043137.1	hypothetical protein	-
OCUBac02_RS01140	230412..230999	+	588	WP_173043138.1	hypothetical protein	-
OCUBac02_RS01145	231270..231512	+	243	WP_173043139.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Genomic island	-	-	223967..237654	13687

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• PIN domain (8-115)

Antitoxin

• SinI-like, DNA-binding domain (76-122)

Sequences

Toxin

Protein

• Length: 192 a.a.
• Molecular weight: 21334.57 Da
• Isoelectric Point: 4.7709

>T36583 WP_173049218.1 NZ_AP022848:226907-227482 [Bosea sp. ANAM02]
IRVAGYTVILDACVLYPAPLRDFLLELAGSGIFRARWTDRIHDEWIRNLLAKRPELDPARLVRTREKMNDAVLGCIVEDY
EDLIAAIELPDPDDRHVLAAAIRTGADGIVTFNLKDFPAEVVRRYGLDIIHPDDFLHQQFGLDQAAVVIAASTIRARLKN
PPTTAAQYLDILEAQALPQLVAELRAFADVI

Nucleotide

• Length: 576 bp

>T36583 NZ_AP022848:226907-227482 [Bosea sp. ANAM02]
ATTAGGGTCGCAGGCTATACGGTCATCCTGGACGCCTGCGTCCTCTATCCCGCTCCCTTGCGAGACTTCCTACTGGAGCT
CGCCGGGAGCGGGATTTTTCGCGCGCGCTGGACCGACCGTATCCATGACGAATGGATCCGGAACCTGCTGGCAAAACGCC
CTGAGCTCGATCCGGCTCGGCTCGTTCGTACGCGTGAGAAGATGAATGATGCGGTGCTGGGCTGCATTGTCGAAGACTAT
GAAGATCTAATCGCCGCGATCGAGCTGCCCGATCCCGATGATCGCCATGTGCTCGCCGCAGCGATCCGCACCGGTGCAGA
TGGCATCGTAACCTTTAACCTGAAGGATTTTCCGGCCGAGGTTGTGCGGCGGTATGGGCTCGACATCATCCACCCGGACG
ATTTTCTTCATCAGCAGTTCGGGCTTGATCAGGCTGCGGTTGTCATCGCCGCGAGCACAATACGCGCAAGGCTGAAGAAC
CCTCCGACGACGGCAGCCCAGTATCTCGATATACTTGAGGCTCAAGCTTTACCGCAATTGGTGGCGGAGCTGCGCGCCTT
TGCTGACGTGATCTGA

Antitoxin

Protein

• Length: 147 a.a.
• Molecular weight: 16174.49 Da
• Isoelectric Point: 7.0769

>AT36583 WP_173043133.1 NZ_AP022848:226471-226911 [Bosea sp. ANAM02]
MLKERPGTLVPSRADAEMATEASRTLARHRGGPLRIRLDDGAELPLPTGVVDLLKHILTETADGNAVTLIPLHAELTTRQ
AAEYLNVSRPHVVKLIEEGRLPHTKVGTHRRIRFTDLEAFKATQDARRREALDALAAEAQELEMGY

Nucleotide

• Length: 441 bp

>AT36583 NZ_AP022848:226471-226911 [Bosea sp. ANAM02]
ATGCTGAAAGAACGCCCCGGCACCTTGGTCCCATCTCGCGCTGATGCAGAGATGGCGACGGAGGCTAGCCGCACGCTTGC
CCGCCATCGTGGCGGCCCCTTGCGTATTCGGCTCGACGATGGTGCGGAGCTGCCGCTGCCGACTGGCGTCGTCGATTTGC
TGAAGCACATCCTGACGGAGACCGCTGACGGCAACGCCGTCACACTGATCCCGCTACATGCTGAACTGACCACCCGGCAG
GCGGCGGAATACCTCAATGTTTCTCGCCCGCATGTGGTGAAGCTTATCGAGGAAGGCCGTCTTCCACATACCAAGGTCGG
CACGCACCGCCGGATTAGGTTCACGGATCTGGAGGCTTTCAAGGCTACCCAGGACGCAAGGCGCCGAGAAGCTCTCGACG
CCTTAGCTGCCGAGGCTCAGGAACTGGAGATGGGCTATTAG