Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) /BrnT(toxin)
Location 201178..201652 Replicon chromosome
Accession NZ_AP022847
Organism Nitrosophilus alvini strain EPR55-1

Toxin (Protein)


Gene name - Uniprot ID -
Locus tag EPR_RS01210 Protein ID WP_200763255.1
Coordinates 201389..201652 (-) Length 88 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID -
Locus tag EPR_RS01205 Protein ID WP_200763253.1
Coordinates 201178..201402 (-) Length 75 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EPR_RS01175 196486..197751 - 1266 WP_200763242.1 DNA polymerase IV -
EPR_RS01180 197838..198500 + 663 WP_200763244.1 phage repressor protein -
EPR_RS01185 198571..199359 + 789 WP_200763246.1 GGDEF domain-containing protein -
EPR_RS01190 199371..199823 + 453 WP_200764125.1 Mut7-C RNAse domain-containing protein -
EPR_RS01195 199834..200079 + 246 WP_200763248.1 helix-hairpin-helix domain-containing protein -
EPR_RS01200 200076..201104 + 1029 WP_200763251.1 UDP-glucose 4-epimerase GalE -
EPR_RS01205 201178..201402 - 225 WP_200763253.1 hypothetical protein Antitoxin
EPR_RS01210 201389..201652 - 264 WP_200763255.1 BrnT family toxin Toxin
EPR_RS01215 201738..203948 - 2211 WP_200763256.1 hypothetical protein -
EPR_RS01220 204017..204886 + 870 WP_200763257.1 chain-length determining protein -
EPR_RS01225 204883..205806 + 924 WP_200763258.1 sugar transferase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Ribonuclease toxin, BrnT, of type II toxin-antitoxin system

(5-80)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 88 a.a.        Molecular weight: 10386.88 Da        Isoelectric Point: 9.8105

>T36581 WP_200763255.1 NZ_AP022847:c201652-201389 [Nitrosophilus alvini]
MNFEYDQNKSRSNKIKHNIDFEEAKKLWNDPDLVEIPAKTTDEQHFVVIGKIGQKFWSAVITYRKGKIRIISVRRSRKEE
IQIYESC

Download         Length: 264 bp

>T36581 NZ_AP022847:c201652-201389 [Nitrosophilus alvini]
ATGAATTTTGAGTACGACCAAAACAAGAGCCGATCTAACAAAATCAAACACAACATAGATTTTGAAGAAGCCAAAAAACT
ATGGAACGATCCTGATTTAGTAGAGATACCGGCAAAAACGACTGATGAACAGCATTTCGTTGTTATAGGAAAAATAGGTC
AGAAGTTCTGGAGTGCCGTAATTACCTACAGAAAAGGCAAAATAAGGATAATTTCGGTCAGAAGATCAAGAAAAGAGGAG
ATACAAATTTATGAAAGCTGCTGA

Antitoxin


Download         Length: 75 a.a.        Molecular weight: 8738.34 Da        Isoelectric Point: 10.0210

>AT36581 WP_200763253.1 NZ_AP022847:c201402-201178 [Nitrosophilus alvini]
MKAAEFDKKFDENESVIEDLDLKKIKKPNLQIKRINIDFPLWLVEKIDKEAKKLGVSRQAIIKMWLAQKVEHGF

Download         Length: 225 bp

>AT36581 NZ_AP022847:c201402-201178 [Nitrosophilus alvini]
ATGAAAGCTGCTGAATTCGATAAAAAATTTGATGAGAACGAGTCTGTAATAGAGGATTTGGATCTTAAAAAGATAAAAAA
ACCGAATCTACAAATAAAACGTATAAATATAGATTTTCCCTTATGGCTTGTTGAAAAAATAGACAAAGAAGCAAAAAAAC
TGGGAGTCTCCCGACAAGCGATCATAAAAATGTGGCTTGCTCAGAAAGTCGAACATGGATTTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References