Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) relBE/YafQ-RelB
Location 1256965..1257500 Replicon chromosome
Accession NZ_AP022846
Organism Haemophilus influenzae strain TAMBA230

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag IGS56_RS06165 Protein ID WP_071163272.1
Coordinates 1257237..1257500 (+) Length 88 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag IGS56_RS06160 Protein ID WP_071163271.1
Coordinates 1256965..1257240 (+) Length 92 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IGS56_RS06140 1252369..1254408 - 2040 WP_071163269.1 excinuclease ABC subunit B -
IGS56_RS06150 1255023..1255991 - 969 WP_071163270.1 zinc transporter permease subunit ZevB -
IGS56_RS06155 1255994..1256614 - 621 WP_005650213.1 zinc transporter binding subunit ZevA -
IGS56_RS06160 1256965..1257240 + 276 WP_071163271.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
IGS56_RS06165 1257237..1257500 + 264 WP_071163272.1 type II toxin-antitoxin system mRNA interferase toxin, RelE/StbE family Toxin
IGS56_RS06170 1257584..1259254 + 1671 WP_005650218.1 energy-dependent translational throttle protein EttA -
IGS56_RS06175 1259317..1259658 + 342 WP_040033872.1 SirB2 family protein -
IGS56_RS06180 1259663..1261633 + 1971 WP_103708111.1 tRNA(Met) cytidine acetyltransferase TmcA -
IGS56_RS06185 1261630..1261803 + 174 WP_005657572.1 DUF5363 domain-containing protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(2-86)

Antitoxin

(1-83)


Sequences


Toxin        


Download         Length: 88 a.a.        Molecular weight: 10201.90 Da        Isoelectric Point: 7.8978

>T36580 WP_071163272.1 NZ_AP022846:1257237-1257500 [Haemophilus influenzae]
MISVSGEYKREFKKHIPLLINSPEYIEVMYCLLNSLPLPEKYKDHALTGNWKGWRDCHIKNDLVLIYKVVGDEIRLARLN
THSEIFG

Download         Length: 264 bp

>T36580 NZ_AP022846:1257237-1257500 [Haemophilus influenzae]
ATGATTTCAGTGAGTGGGGAATATAAAAGAGAATTTAAAAAACATATTCCTCTTCTTATAAATAGTCCAGAATATATTGA
AGTTATGTATTGTCTTTTGAATAGCTTACCATTGCCAGAAAAATATAAAGATCATGCTTTAACTGGAAATTGGAAAGGTT
GGAGAGATTGCCATATAAAGAATGATCTTGTGCTTATTTATAAAGTGGTGGGAGATGAAATAAGGCTGGCTCGTCTTAAT
ACTCATTCAGAAATTTTTGGTTAA

Antitoxin


Download         Length: 92 a.a.        Molecular weight: 10277.84 Da        Isoelectric Point: 6.0646

>AT36580 WP_071163271.1 NZ_AP022846:1256965-1257240 [Haemophilus influenzae]
MAAVSFRVPDETKNMAFEVIKSYGLSPTQALNMFLAQIAKTKAIPVSLDYQTEQMPNSKTIMAMAELDNHHGHEYKTLEE
FHQAMLAEMKS

Download         Length: 276 bp

>AT36580 NZ_AP022846:1256965-1257240 [Haemophilus influenzae]
ATGGCTGCAGTTAGTTTTCGAGTACCTGATGAAACTAAAAATATGGCGTTTGAAGTGATTAAAAGTTACGGTCTTTCCCC
AACTCAAGCACTTAATATGTTTTTAGCTCAAATAGCTAAAACGAAAGCGATTCCAGTATCACTAGATTATCAAACTGAAC
AGATGCCTAACTCAAAAACGATAATGGCTATGGCAGAGTTAGATAATCATCATGGGCATGAATACAAAACATTGGAGGAA
TTCCATCAAGCGATGCTAGCGGAGATGAAATCATGA

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Source ID Structure

References