Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YoeB-YefM
Location 758337..758839 Replicon chromosome
Accession NZ_AP022843
Organism Halomonas hydrothermalis strain Slthf2

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag HHSLTHF2_RS03725 Protein ID WP_172420042.1
Coordinates 758337..758591 (-) Length 85 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag HHSLTHF2_RS03730 Protein ID WP_172420043.1
Coordinates 758588..758839 (-) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HHSLTHF2_RS03685 753355..754584 + 1230 WP_172420037.1 hypothetical protein -
HHSLTHF2_RS03690 754581..755447 + 867 WP_172420038.1 hypothetical protein -
HHSLTHF2_RS03695 755515..755793 + 279 WP_197915485.1 hypothetical protein -
HHSLTHF2_RS03700 755867..756157 - 291 WP_172420039.1 type II toxin-antitoxin system RelE/ParE family toxin -
HHSLTHF2_RS03705 756150..756371 - 222 WP_120385726.1 hypothetical protein -
HHSLTHF2_RS03710 756671..756949 + 279 WP_172420040.1 type II toxin-antitoxin system RelE/ParE family toxin -
HHSLTHF2_RS03715 756949..757242 + 294 WP_009722157.1 HigA family addiction module antidote protein -
HHSLTHF2_RS03720 757359..758321 + 963 WP_172420041.1 ribonuclease Z -
HHSLTHF2_RS03725 758337..758591 - 255 WP_172420042.1 Txe/YoeB family addiction module toxin Toxin
HHSLTHF2_RS03730 758588..758839 - 252 WP_172420043.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
HHSLTHF2_RS03735 759003..760199 - 1197 WP_172420044.1 homoserine O-acetyltransferase -
HHSLTHF2_RS03740 760275..761447 - 1173 WP_172420045.1 UbiH/UbiF/VisC/COQ6 family ubiquinone biosynthesis hydroxylase -
HHSLTHF2_RS03745 761563..762411 + 849 WP_172420046.1 NAD-dependent protein deacetylase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-74)


Sequences

Toxin        


Download         Length: 85 a.a.        Molecular weight: 10176.79 Da        Isoelectric Point: 9.8352

>T36572 WP_172420042.1 NZ_AP022843:c758591-758337 [Halomonas hydrothermalis]
MKLIFAEHAWEDYLYWQKTDKKVLSRINKLIKETQREPFGGVGKPEPLKHGLASYWSRRINEEHRMIYKVTDEALLIAQL
RYHY

Download         Length: 255 bp

>T36572 NZ_AP022843:c758591-758337 [Halomonas hydrothermalis]
ATGAAGCTCATCTTCGCTGAGCATGCCTGGGAAGATTATTTATACTGGCAGAAAACGGACAAAAAAGTGCTCAGTCGCAT
CAATAAGCTAATCAAAGAAACCCAGCGAGAACCCTTTGGCGGCGTTGGTAAACCAGAGCCCCTTAAACACGGCTTGGCGA
GTTACTGGTCTCGACGCATCAACGAAGAGCACCGGATGATTTACAAGGTGACTGACGAAGCGCTGCTGATCGCCCAGCTT
CGGTATCACTACTGA

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9281.53 Da        Isoelectric Point: 4.2837

>AT36572 WP_172420043.1 NZ_AP022843:c758839-758588 [Halomonas hydrothermalis]
MDAISYTAARTNLAKTMQQVCEDHAPMIITRNKAQSVVMISLEDYEALQETAYLLRAPKNAQRLLESIAELEQGGGQEQE
LLE

Download         Length: 252 bp

>AT36572 NZ_AP022843:c758839-758588 [Halomonas hydrothermalis]
ATGGATGCCATTAGCTACACAGCAGCTAGAACCAATCTAGCGAAAACAATGCAACAGGTCTGCGAAGATCACGCGCCCAT
GATCATTACCCGTAATAAAGCGCAGTCTGTGGTCATGATCTCTTTAGAGGATTATGAGGCACTGCAAGAGACCGCCTACC
TGCTGCGCGCCCCCAAAAACGCTCAACGTTTGCTTGAATCGATTGCCGAGCTAGAGCAAGGTGGCGGCCAAGAGCAGGAG
CTTTTGGAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References