Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YafQ-RelB
Location 2394216..2394781 Replicon chromosome
Accession NZ_AP022829
Organism Adlercreutzia sp. 8CFCBH1

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag HRR28_RS10140 Protein ID WP_114548667.1
Coordinates 2394488..2394781 (+) Length 98 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag HRR28_RS10135 Protein ID WP_114548668.1
Coordinates 2394216..2394485 (+) Length 90 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HRR28_RS10125 2391641..2392954 + 1314 WP_139913199.1 IS21 family transposase -
HRR28_RS10130 2392957..2393769 + 813 WP_117285288.1 ATP-binding protein -
HRR28_RS10135 2394216..2394485 + 270 WP_114548668.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
HRR28_RS10140 2394488..2394781 + 294 WP_114548667.1 type II toxin-antitoxin system YafQ family toxin Toxin
HRR28_RS10145 2394926..2395576 - 651 WP_173114156.1 DNA mismatch endonuclease Vsr -
HRR28_RS10150 2395860..2396753 + 894 WP_197745950.1 M15 family metallopeptidase -
HRR28_RS10155 2396907..2397806 - 900 WP_114548665.1 polysulfide reductase NrfD -
HRR28_RS10160 2397812..2398354 - 543 WP_041714836.1 4Fe-4S dicluster domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, YafQ-like toxin

(4-95)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(1-68)


Sequences

Toxin        


Download         Length: 98 a.a.        Molecular weight: 11172.64 Da        Isoelectric Point: 8.1046

>T36559 WP_114548667.1 NZ_AP022829:2394488-2394781 [Adlercreutzia sp. 8CFCBH1]
VLRANYTPRFQKDVKRLKKKHVALDPLKEVVELVVADTPDSRSELVRRHNMHRLKGEWSGSMECHVANAGDWLLVWAQTD
DQAYFQRTGGHDDLFSG

Download         Length: 294 bp

>T36559 NZ_AP022829:2394488-2394781 [Adlercreutzia sp. 8CFCBH1]
GTGCTGAGAGCCAATTACACCCCGCGCTTCCAGAAAGACGTTAAGCGCCTTAAGAAGAAGCACGTAGCGCTAGATCCTCT
GAAAGAAGTCGTGGAATTGGTGGTCGCCGATACCCCAGATAGCCGATCAGAACTTGTTCGCCGGCATAATATGCATCGGC
TCAAAGGCGAGTGGTCGGGAAGCATGGAATGCCATGTCGCAAACGCTGGCGACTGGTTGCTTGTTTGGGCGCAGACCGAC
GATCAGGCGTACTTTCAGAGAACCGGTGGCCACGACGATCTGTTCAGTGGATAG

Antitoxin


Download         Length: 90 a.a.        Molecular weight: 9902.12 Da        Isoelectric Point: 4.3575

>AT36559 WP_114548668.1 NZ_AP022829:2394216-2394485 [Adlercreutzia sp. 8CFCBH1]
MATASVTVRVDEDTKRAAANIVEDFGFDLSSVTRAFYRQIVREQRIPLTLEYPTPNLESREAIRETKELIASGDPGYATV
SEMFEAMGA

Download         Length: 270 bp

>AT36559 NZ_AP022829:2394216-2394485 [Adlercreutzia sp. 8CFCBH1]
ATGGCAACTGCTTCTGTAACGGTGAGAGTCGACGAAGATACCAAGCGCGCCGCAGCTAACATCGTGGAAGATTTCGGCTT
CGATCTCTCATCAGTCACGCGCGCGTTCTACCGTCAGATCGTACGCGAGCAGCGCATTCCCCTCACGCTTGAATATCCAA
CGCCTAATCTCGAGTCTCGCGAGGCAATAAGGGAAACGAAAGAACTCATCGCATCGGGAGATCCGGGCTACGCCACCGTA
TCAGAAATGTTCGAGGCGATGGGAGCATAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References