Detailed information of TA system TA036553

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): vapBC/VapC-StbC
• Location: 2649699..2650387
• Replicon: chromosome
• Accession: NZ_AP022821
• Organism: Halomonas meridiana strain Slthf1

Toxin (Protein)

• Gene name: vapC
• Uniprot ID: -
• Locus tag: HMSLTHF_RS12450
• Protein ID: WP_172416421.1
• Coordinates: 2649699..2650145 (-)
• Length: 149 a.a.

Antitoxin (Protein)

• Gene name: vapB
• Uniprot ID: -
• Locus tag: HMSLTHF_RS12455
• Protein ID: WP_172416422.1
• Coordinates: 2650142..2650387 (-)
• Length: 82 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• PIN domain (2-120)

Antitoxin

• Arc-like DNA binding domain (9-46)

Sequences

Toxin

Protein

• Length: 149 a.a.
• Molecular weight: 15886.18 Da
• Isoelectric Point: 4.7414

>T36553 WP_172416421.1 NZ_AP022821:c2650145-2649699 [Halomonas meridiana]
MILLDISIISELLRDTPAAQVIEWIDAQPLETLYLSATTVAALQAAVARLPSEERRAHVHAGLEKRLLPLFAGRILPFDQ
SCTRAYAEAITKVEKGGSEILPVDGYIAAIAAVNGLIVAARETAAFEAAGVETINPWQKHSQSDNAAQ

Nucleotide

• Length: 447 bp

>T36553 NZ_AP022821:c2650145-2649699 [Halomonas meridiana]
ATGATTTTGCTCGACATCAGCATCATCAGCGAGTTGCTGCGCGACACGCCAGCGGCACAGGTCATCGAGTGGATCGATGC
CCAACCGCTGGAAACGCTCTATTTGTCTGCCACCACCGTTGCAGCGTTGCAGGCCGCTGTAGCGCGGCTCCCCTCGGAAG
AACGGCGTGCCCATGTACATGCAGGCCTGGAGAAGCGGCTACTACCCCTATTTGCAGGGCGGATTCTTCCTTTCGACCAG
TCATGCACAAGGGCCTATGCCGAAGCGATAACCAAGGTCGAAAAAGGCGGCAGCGAAATACTTCCGGTAGATGGCTACAT
CGCTGCGATAGCGGCAGTAAACGGTCTGATCGTAGCAGCGCGAGAAACCGCAGCTTTCGAGGCGGCGGGCGTGGAGACCA
TCAACCCGTGGCAAAAACACAGCCAGAGCGATAACGCCGCTCAGTAA

Antitoxin

Protein

• Length: 82 a.a.
• Molecular weight: 8720.09 Da
• Isoelectric Point: 7.3197

>AT36553 WP_172416422.1 NZ_AP022821:c2650387-2650142 [Halomonas meridiana]
MAMLTVRNLPDEVHRALRVRAALHGHSMEAEVREILEAAVAPEGRVKLGSLLADIGKQAKLTDKELASFGSTRAGYPVGI
E

Nucleotide

• Length: 246 bp

>AT36553 NZ_AP022821:c2650387-2650142 [Halomonas meridiana]
ATGGCCATGCTGACTGTTCGCAACCTTCCTGATGAGGTACACCGTGCCTTGCGTGTCCGTGCAGCTCTGCACGGGCACAG
CATGGAGGCCGAGGTGCGCGAGATCCTGGAAGCTGCTGTAGCGCCCGAGGGGCGGGTCAAGCTGGGCTCTCTGCTGGCCG
ACATAGGCAAGCAGGCCAAGCTGACCGATAAAGAGCTGGCATCCTTCGGATCGACTCGCGCTGGGTACCCGGTTGGCATC
GAATGA