Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yoeB-relB/YoeB-YefM
Location 950723..951225 Replicon chromosome
Accession NZ_AP022821
Organism Halomonas meridiana strain Slthf1

Toxin (Protein)


Gene name yoeB Uniprot ID A0A4U3CA92
Locus tag HMSLTHF_RS04555 Protein ID WP_044627928.1
Coordinates 950723..950977 (-) Length 85 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A510J541
Locus tag HMSLTHF_RS04560 Protein ID WP_044627927.1
Coordinates 950974..951225 (-) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- flank IS/Tn - - 946994..947362 368


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-83)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-74)


Sequences

Toxin        


Download         Length: 85 a.a.        Molecular weight: 10182.73 Da        Isoelectric Point: 9.8876

>T36549 WP_044627928.1 NZ_AP022821:c950977-950723 [Halomonas meridiana]
MKLIFSENAWEDYLYWQKTDKKILNRINKLIKETKREPFEGVGKPEPLKHSLAGYWSRRINEEHRIAYKVTDDALLIAQL
RYHH

Download         Length: 255 bp

>T36549 NZ_AP022821:c950977-950723 [Halomonas meridiana]
ATGAAACTCATCTTCTCCGAGAACGCCTGGGAAGACTATCTGTACTGGCAGAAAACCGACAAAAAGATACTTAACCGAAT
CAACAAACTGATCAAAGAGACCAAACGAGAACCGTTCGAAGGTGTTGGCAAACCAGAGCCCCTCAAACACAGCCTCGCCG
GGTACTGGTCTCGCCGGATCAACGAAGAACACCGAATAGCTTACAAAGTCACGGATGACGCTTTGCTTATCGCCCAGCTC
CGGTATCACCACTGA

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9296.52 Da        Isoelectric Point: 4.4750

>AT36549 WP_044627927.1 NZ_AP022821:c951225-950974 [Halomonas meridiana]
MDAISYTAARTNLAKTMEQVCEDHSPVIITRNKSQSVVMISLEDYEALQETAYLLRAPKNARRLLESVAELEQGGGQEKE
LLE

Download         Length: 252 bp

>AT36549 NZ_AP022821:c951225-950974 [Halomonas meridiana]
ATGGATGCCATTAGCTACACAGCCGCTAGAACCAATCTAGCAAAAACCATGGAGCAGGTCTGTGAAGACCATTCCCCTGT
GATCATCACCCGGAACAAGTCGCAGTCCGTGGTAATGATCTCCCTAGAGGACTACGAGGCGCTGCAAGAGACTGCATACC
TTCTGCGCGCACCAAAAAACGCACGGCGTTTGCTGGAATCCGTTGCCGAGCTGGAGCAAGGCGGTGGTCAAGAAAAGGAA
CTTCTTGAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A4U3CA92

Antitoxin

Source ID Structure
AlphaFold DB A0A510J541

References