Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/Phd(antitoxin)
Location 949520..950067 Replicon chromosome
Accession NZ_AP022821
Organism Halomonas meridiana strain Slthf1

Toxin (Protein)


Gene name relE Uniprot ID A0A455V9X0
Locus tag HMSLTHF_RS04540 Protein ID WP_061332717.1
Coordinates 949765..950067 (+) Length 101 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID U7NTA2
Locus tag HMSLTHF_RS04535 Protein ID WP_022992576.1
Coordinates 949520..949777 (+) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 931171..950455 19284
- flank IS/Tn - - 946994..947362 368
- inside Integron - - 947842..950455 2613


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-91)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-72)


Sequences

Toxin        


Download         Length: 101 a.a.        Molecular weight: 11663.41 Da        Isoelectric Point: 4.5702

>T36548 WP_061332717.1 NZ_AP022821:949765-950067 [Halomonas meridiana]
MAEVIWTEPALQELDAIAEYIALDNPVAASHLVQEVFDKTERLEDFPQSGRIPPELPNSVYREVVVPPCRIFYREDKKRV
LVLYVMREERQLRAYMLGNS

Download         Length: 303 bp

>T36548 NZ_AP022821:949765-950067 [Halomonas meridiana]
ATGGCTGAAGTAATCTGGACGGAGCCTGCTCTGCAAGAACTGGATGCCATCGCTGAGTACATTGCTCTGGATAATCCTGT
TGCCGCAAGTCATCTGGTCCAAGAAGTTTTCGATAAGACCGAGCGCTTGGAAGATTTTCCCCAATCCGGACGGATTCCTC
CAGAGCTCCCTAATTCGGTATACAGGGAGGTAGTGGTTCCACCGTGTCGCATTTTTTATCGTGAGGATAAGAAGCGGGTT
CTCGTCCTCTATGTCATGCGAGAGGAGCGGCAGCTTCGTGCGTACATGCTTGGGAACAGCTAA

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9901.44 Da        Isoelectric Point: 8.5042

>AT36548 WP_022992576.1 NZ_AP022821:949520-949777 [Halomonas meridiana]
MKVELVTNLKRQATKILADLHLSKEPILITEHGQPSAYLVDVQDYEFMQRRLELLEGLSRGERAVLEGRTYSQSEAREKM
SKWLK

Download         Length: 258 bp

>AT36548 NZ_AP022821:949520-949777 [Halomonas meridiana]
ATGAAAGTTGAGCTTGTTACGAACCTCAAGCGCCAAGCCACAAAGATTCTGGCAGATCTGCACTTGTCTAAAGAGCCGAT
ACTGATCACGGAGCATGGTCAGCCATCGGCATATCTTGTCGATGTGCAGGATTACGAGTTTATGCAGCGCCGACTTGAGC
TGCTTGAGGGGCTCTCACGGGGAGAGCGTGCTGTACTTGAGGGAAGAACGTACAGCCAAAGTGAGGCCAGGGAGAAAATG
AGTAAATGGCTGAAGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A455V9X0

Antitoxin

Source ID Structure
AlphaFold DB A0A455VBQ8

References