Detailed information of TA system TA036547

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/RelE(toxin)
• Location: 844345..844814
• Replicon: chromosome
• Accession: NZ_AP022821
• Organism: Halomonas meridiana strain Slthf1

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: HMSLTHF_RS04045
• Protein ID: WP_054641355.1
• Coordinates: 844539..844814 (+)
• Length: 92 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: HMSLTHF_RS04040
• Protein ID: WP_054641354.1
• Coordinates: 844345..844542 (+)
• Length: 66 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
HMSLTHF_RS04025	839986..841278	-	1293	WP_054641353.1	lysine N(6)-hydroxylase/L-ornithine N(5)-oxygenase family protein	-
HMSLTHF_RS04030	841302..842432	-	1131	WP_172416724.1	GNAT family N-acetyltransferase	-
HMSLTHF_RS04035	842594..844234	+	1641	Protein_787	cyclic peptide export ABC transporter	-
HMSLTHF_RS04040	844345..844542	+	198	WP_054641354.1	hypothetical protein	Antitoxin
HMSLTHF_RS04045	844539..844814	+	276	WP_054641355.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
HMSLTHF_RS04050	845056..845679	-	624	WP_054641356.1	cytochrome b	-
HMSLTHF_RS04055	845672..846616	-	945	WP_058578660.1	siderophore-interacting protein	-
HMSLTHF_RS04060	846815..848806	+	1992	WP_058578659.1	Fe(3+)-hydroxamate ABC transporter permease FhuB	-
HMSLTHF_RS04065	848803..849591	+	789	WP_058578658.1	siderophore-iron reductase FhuF	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (5-90)

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 92 a.a.
• Molecular weight: 10487.97 Da
• Isoelectric Point: 6.7581

>T36547 WP_054641355.1 NZ_AP022821:844539-844814 [Halomonas meridiana]
VSLPIHWHDEAINDLFELVVYIAERDPQAARRLRIRIEAAVSSVAEHPYLHQVGRLPGTREIVAHPNFIVVYQVTDRIEV
ISVVHSRQNYP

Nucleotide

• Length: 276 bp

>T36547 NZ_AP022821:844539-844814 [Halomonas meridiana]
GTGAGCCTGCCTATCCACTGGCATGACGAGGCGATTAACGACTTGTTTGAGCTTGTCGTATACATCGCCGAGCGCGATCC
TCAAGCCGCCCGGCGGCTGCGTATTCGTATTGAAGCAGCTGTCTCCTCAGTGGCTGAACACCCCTACTTACACCAAGTGG
GCCGCTTGCCGGGTACGCGAGAAATTGTTGCTCACCCAAACTTTATCGTGGTCTACCAAGTGACGGATCGCATTGAGGTC
ATATCAGTGGTTCACTCTCGCCAAAATTATCCCTGA

Antitoxin

Protein

• Length: 66 a.a.
• Molecular weight: 7331.11 Da
• Isoelectric Point: 4.4278

>AT36547 WP_054641354.1 NZ_AP022821:844345-844542 [Halomonas meridiana]
MNTQLDPIVSEFETQEQADSYDRWLKAKVQRSIDNPGQGMPHDQVMTKVDAIIADAEQRQRGGVS

Nucleotide

• Length: 198 bp

>AT36547 NZ_AP022821:844345-844542 [Halomonas meridiana]
ATGAATACCCAGCTAGATCCTATCGTTTCGGAATTCGAGACGCAGGAACAAGCCGATAGCTATGATCGTTGGCTCAAGGC
CAAAGTTCAGCGCAGCATCGACAACCCGGGCCAAGGAATGCCTCATGACCAAGTTATGACCAAGGTTGATGCGATCATCG
CCGACGCGGAGCAACGCCAACGCGGCGGAGTTTCGTGA