Detailed information of TA system TA036546

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): /BrnT(toxin)
• Location: 580031..580553
• Replicon: chromosome
• Accession: NZ_AP022821
• Organism: Halomonas meridiana strain Slthf1

Toxin (Protein)

• Gene name: -
• Uniprot ID: A0A2M9TBV7
• Locus tag: HMSLTHF_RS02895
• Protein ID: WP_058578261.1
• Coordinates: 580031..580294 (+)
• Length: 88 a.a.

Antitoxin (Protein)

• Gene name: -
• Uniprot ID: -
• Locus tag: HMSLTHF_RS02900
• Protein ID: WP_137094295.1
• Coordinates: 580284..580553 (+)
• Length: 90 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Ribonuclease toxin, BrnT, of type II toxin-antitoxin system (6-81)

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 88 a.a.
• Molecular weight: 10314.77 Da
• Isoelectric Point: 7.2035

>T36546 WP_058578261.1 NZ_AP022821:580031-580294 [Halomonas meridiana]
MNEFEFDVNKSQANLTKHGIDFEAAQALWKDPYLLEIRAKSEGEPRFLLIGMISEKHWSAVVTYREERIRLISVRRSRKK
EVDIYES

Nucleotide

• Length: 264 bp

>T36546 NZ_AP022821:580031-580294 [Halomonas meridiana]
ATGAACGAGTTCGAGTTTGACGTCAACAAAAGTCAGGCCAACCTGACAAAGCACGGTATTGATTTTGAAGCGGCACAAGC
GCTGTGGAAGGATCCATATCTGCTAGAAATTCGCGCAAAATCCGAGGGCGAACCAAGGTTTTTGCTAATCGGTATGATCA
GTGAAAAACATTGGTCGGCAGTCGTCACCTACCGAGAAGAGCGTATTCGGCTGATTTCTGTTAGACGCTCCCGCAAGAAG
GAGGTAGACATCTATGAAAGCTAA

Antitoxin

Protein

• Length: 90 a.a.
• Molecular weight: 10301.57 Da
• Isoelectric Point: 6.8810

>AT36546 WP_137094295.1 NZ_AP022821:580284-580553 [Halomonas meridiana]
MKAKEFDKKFDENQYDVLDDLDFSTARRVNQEQKRINVDFPAWVVESLDREAARMGVTRQSIIKVWLVERLQAEAAHKPH
GHNSVGGPH

Nucleotide

• Length: 270 bp

>AT36546 NZ_AP022821:580284-580553 [Halomonas meridiana]
ATGAAAGCTAAAGAGTTCGATAAAAAATTCGATGAAAATCAATATGATGTTCTCGATGATCTAGACTTTTCCACTGCTCG
ACGGGTGAATCAGGAGCAAAAGCGGATTAACGTAGATTTTCCTGCATGGGTAGTGGAGTCACTAGACCGTGAGGCTGCGA
GAATGGGTGTTACCCGCCAGTCGATTATCAAGGTTTGGTTAGTGGAGCGTCTGCAAGCTGAAGCGGCTCATAAACCTCAT
GGCCATAACTCAGTAGGGGGACCTCACTAG

Structures

Toxin

• AlphaFold DB: A0A2M9TBV7