Detailed information of TA system TA036487

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): pasABC/RelE-HTH
• Location: 3141324..3141810
• Replicon: chromosome
• Accession: NZ_AP022810
• Organism: Desulfuromonas sp. AOP6

Toxin (Protein)

• Gene name: pasB
• Uniprot ID: -
• Locus tag: AOP6_RS14690
• Protein ID: WP_155877476.1
• Coordinates: 3141538..3141810 (+)
• Length: 91 a.a.

Antitoxin (Protein)

• Gene name: pasA
• Uniprot ID: -
• Locus tag: AOP6_RS14685
• Protein ID: WP_155877475.1
• Coordinates: 3141324..3141554 (+)
• Length: 77 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
AOP6_RS14675 (AOP6_2894)	3138021..3139688	-	1668	WP_213194640.1	VCBS repeat-containing protein	-
AOP6_RS14680 (AOP6_2895)	3139847..3140866	-	1020	WP_155877474.1	hypothetical protein	-
AOP6_RS15325 (AOP6_2896)	3140955..3141086	-	132	WP_256439347.1	hypothetical protein	-
AOP6_RS14685 (AOP6_2897)	3141324..3141554	+	231	WP_155877475.1	DUF6290 family protein	Antitoxin
AOP6_RS14690 (AOP6_2898)	3141538..3141810	+	273	WP_155877476.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
AOP6_RS14695 (AOP6_2899)	3141897..3143072	-	1176	WP_213194641.1	rhodanese-like domain-containing protein	-
AOP6_RS14700 (AOP6_2900)	3143356..3145095	-	1740	WP_155877478.1	VCBS repeat-containing protein	-
AOP6_RS14705 (AOP6_2901)	3145218..3146510	-	1293	WP_155877479.1	hypothetical protein	-
AOP6_RS14710 (AOP6_2902)	3146549..3146695	-	147	WP_155877480.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (5-88)

Antitoxin

• Protein of unknown function DUF6290 (1-72)

Sequences

Toxin

Protein

• Length: 91 a.a.
• Molecular weight: 10716.37 Da
• Isoelectric Point: 10.9637

>T36487 WP_155877476.1 NZ_AP022810:3141538-3141810 [Desulfuromonas sp. AOP6]
MSWNIEFDPAAARELRKLDRQVARRLLHFLSDRIAHLDDPRSLGEALKGSRFGDFWKYRVGDYRIIASIQDKKFLILVVR
IGNRRDVYQR

Nucleotide

• Length: 273 bp

>T36487 NZ_AP022810:3141538-3141810 [Desulfuromonas sp. AOP6]
TTGAGCTGGAACATTGAATTTGATCCGGCGGCGGCCCGCGAACTGCGAAAACTCGATCGCCAAGTCGCCCGGCGCCTTCT
ACATTTTCTCTCCGACCGTATCGCTCACCTTGATGATCCACGCAGTCTTGGCGAAGCGCTGAAGGGGAGTCGATTTGGCG
ATTTCTGGAAATATCGTGTGGGTGATTATCGTATTATCGCCAGCATTCAGGACAAAAAATTCCTCATCCTCGTCGTCAGG
ATAGGAAACAGGCGAGACGTCTACCAGCGGTGA

Antitoxin

Protein

• Length: 77 a.a.
• Molecular weight: 8937.10 Da
• Isoelectric Point: 5.1898

>AT36487 WP_155877475.1 NZ_AP022810:3141324-3141554 [Desulfuromonas sp. AOP6]
MKTVNVRVSDEVAERLDKLAQETHRTKSYYLRKIIEDHLEDLEDAYLAQQRLEDIRAGKTKTIPLSEVEKSLELEH

Nucleotide

• Length: 231 bp

>AT36487 NZ_AP022810:3141324-3141554 [Desulfuromonas sp. AOP6]
ATGAAAACAGTTAATGTCAGGGTTTCCGACGAGGTCGCTGAACGGCTGGATAAACTTGCGCAGGAGACCCATCGCACCAA
AAGCTATTATCTGCGCAAAATCATAGAGGATCATCTGGAAGATCTGGAAGACGCGTACCTCGCGCAACAGCGCCTGGAAG
ATATCCGCGCCGGAAAGACAAAAACAATTCCCCTGAGCGAGGTTGAGAAGAGCCTTGAGCTGGAACATTGA