Detailed information of TA system TA036486

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relE-pasA/RelE-HTH
• Location: 2609542..2610007
• Replicon: chromosome
• Accession: NZ_AP022810
• Organism: Desulfuromonas sp. AOP6

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: AOP6_RS12305
• Protein ID: WP_155877053.1
• Coordinates: 2609542..2609811 (-)
• Length: 90 a.a.

Antitoxin (Protein)

• Gene name: pasA
• Uniprot ID: -
• Locus tag: AOP6_RS12310
• Protein ID: WP_155877054.1
• Coordinates: 2609795..2610007 (-)
• Length: 71 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
AOP6_RS12290 (AOP6_2426)	2605766..2606626	+	861	WP_155877050.1	mechanosensitive ion channel	-
AOP6_RS12295 (AOP6_2427)	2606623..2607852	+	1230	WP_155877051.1	SLC13 family permease	-
AOP6_RS12300 (AOP6_2428)	2607872..2609335	+	1464	WP_155877052.1	FAD-binding domain-containing protein	-
AOP6_RS12305 (AOP6_2429)	2609542..2609811	-	270	WP_155877053.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
AOP6_RS12310 (AOP6_2430)	2609795..2610007	-	213	WP_155877054.1	DUF6290 family protein	Antitoxin
AOP6_RS12315 (AOP6_2431)	2610079..2610978	-	900	WP_213194585.1	transposase	-
AOP6_RS12320 (AOP6_2432)	2611201..2613168	-	1968	WP_213194586.1	hypothetical protein	-
AOP6_RS12325 (AOP6_2433)	2613216..2614037	-	822	WP_155877056.1	cytochrome c3 family protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (9-87)

Antitoxin

• Protein of unknown function DUF6290 (3-65)

Sequences

Toxin

Protein

• Length: 90 a.a.
• Molecular weight: 10463.23 Da
• Isoelectric Point: 9.7435

>T36486 WP_155877053.1 NZ_AP022810:c2609811-2609542 [Desulfuromonas sp. AOP6]
MGWTIEIDAFAEKQLRKLDKSVQKRLLGWLADRIEGCKNPRHFGEPLRGDLSGLWRYRVGDFRIICEIQDEKLVVLALAI
GHRREIYVR

Nucleotide

• Length: 270 bp

>T36486 NZ_AP022810:c2609811-2609542 [Desulfuromonas sp. AOP6]
TTGGGCTGGACGATTGAAATCGACGCGTTTGCCGAGAAGCAACTGCGCAAATTGGACAAGTCTGTTCAGAAACGTCTGTT
GGGTTGGCTTGCGGATCGCATTGAGGGATGCAAAAACCCCCGCCATTTTGGGGAGCCGCTTCGGGGGGATTTGTCCGGCC
TATGGCGCTACCGGGTGGGTGATTTCAGAATCATCTGCGAGATTCAAGATGAAAAGCTGGTTGTCCTTGCCTTGGCCATT
GGCCACCGCCGCGAAATCTATGTGCGCTGA

Antitoxin

Protein

• Length: 71 a.a.
• Molecular weight: 7974.13 Da
• Isoelectric Point: 5.8770

>AT36486 WP_155877054.1 NZ_AP022810:c2610007-2609795 [Desulfuromonas sp. AOP6]
MLAIRLEKELEHELDLVAKARKSSRSAVVREAIVRYLEDNEDLALARQALAENGTRKSLKELRKDLGLDD

Nucleotide

• Length: 213 bp

>AT36486 NZ_AP022810:c2610007-2609795 [Desulfuromonas sp. AOP6]
ATGCTGGCAATTCGACTGGAAAAAGAACTTGAGCACGAACTGGACTTGGTTGCCAAGGCCCGCAAAAGCAGCCGTAGTGC
TGTTGTTCGTGAGGCGATCGTTCGTTATCTTGAAGACAATGAGGATTTGGCTTTGGCCCGGCAGGCACTGGCTGAAAACG
GCACGCGGAAATCTCTCAAAGAGCTGAGGAAAGATCTTGGGCTGGACGATTGA