Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE-RelB
Location 360219..360778 Replicon chromosome
Accession NZ_AP022810
Organism Desulfuromonas sp. AOP6

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag AOP6_RS01730 Protein ID WP_155874921.1
Coordinates 360500..360778 (+) Length 93 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag AOP6_RS01725 Protein ID WP_155874920.1
Coordinates 360219..360503 (+) Length 95 a.a.

Genomic Context

AOP6_RS01725AOP6_RS01730AOP6_RS01690AOP6_RS01695AOP6_RS01700AOP6_RS01705AOP6_RS01710AOP6_RS01715AOP6_RS01720AOP6_RS01735AOP6_RS01740AOP6_RS01745AOP6_RS01750AOP6_RS01755AOP6_RS01760
Location: 360219..360503 (285 bp)
Type: Antitoxin
Protein ID: WP_155874920.1
Location: 360500..360778 (279 bp)
Type: Toxin
Protein ID: WP_155874921.1
Location: 355537..356175 (639 bp)
Type: Others
Protein ID: WP_155874913.1
Location: 356353..356640 (288 bp)
Type: Others
Protein ID: WP_155874914.1
Location: 356735..357043 (309 bp)
Type: Others
Protein ID: WP_155874915.1
Location: 357386..357736 (351 bp)
Type: Others
Protein ID: WP_213194714.1
Location: 357975..358757 (783 bp)
Type: Others
Protein ID: WP_155874917.1
Location: 358836..359291 (456 bp)
Type: Others
Protein ID: WP_155874918.1
Location: 359396..359956 (561 bp)
Type: Others
Protein ID: WP_155874919.1
Location: 360901..361608 (708 bp)
Type: Others
Protein ID: WP_155874922.1
Location: 361756..362052 (297 bp)
Type: Others
Protein ID: WP_155874923.1
Location: 362124..362879 (756 bp)
Type: Others
Protein ID: WP_155874924.1
Location: 363515..364078 (564 bp)
Type: Others
Protein ID: WP_155874925.1
Location: 364175..364669 (495 bp)
Type: Others
Protein ID: WP_155874926.1
Location: 365163..365474 (312 bp)
Type: Others
Protein ID: WP_155874927.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
AOP6_RS01690 (AOP6_0344)355537..356175-639WP_155874913.1hypothetical protein-
AOP6_RS01695 (AOP6_0345)356353..356640-288WP_155874914.1coiled coil domain-containing protein-
AOP6_RS01700 (AOP6_0346)356735..357043-309WP_155874915.1ferritin family protein-
AOP6_RS01705 (AOP6_0347)357386..357736-351WP_213194714.1DUF1622 domain-containing protein-
AOP6_RS01710 (AOP6_0348)357975..358757-783WP_155874917.1MipA/OmpV family protein-
AOP6_RS01715 (AOP6_0349)358836..359291-456WP_155874918.1hypothetical protein-
AOP6_RS01720 (AOP6_0350)359396..359956-561WP_155874919.1hypothetical protein-
AOP6_RS01725 (AOP6_0351)360219..360503+285WP_155874920.1type II toxin-antitoxin system RelB/DinJ family antitoxinAntitoxin
AOP6_RS01730360500..360778+279WP_155874921.1type II toxin-antitoxin system RelE/ParE family toxinToxin
AOP6_RS01735 (AOP6_0352)360901..361608-708WP_155874922.1hypothetical protein-
AOP6_RS01740 (AOP6_0353)361756..362052-297WP_155874923.1hypothetical protein-
AOP6_RS01745 (AOP6_0354)362124..362879-756WP_155874924.1hypothetical protein-
AOP6_RS01750 (AOP6_0355)363515..364078-564WP_155874925.1hypothetical protein-
AOP6_RS01755 (AOP6_0356)364175..364669-495WP_155874926.1hypothetical protein-
AOP6_RS01760 (AOP6_0357)365163..365474-312WP_155874927.1hypothetical protein-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(2-89)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(5-77)


Sequences

Toxin        


Download         Length: 93 a.a.        Molecular weight: 10797.49 Da        Isoelectric Point: 4.4508

>T36485 WP_155874921.1 NZ_AP022810:360500-360778 [Desulfuromonas sp. AOP6]
MIFWEEESLNDREKIFEFLYVFNPDAAEKADEIIEAKVENLIEQPLMGVQREGIRGRLLIIPEVSMVVSYFVDGSTIRIL
RVLHQKQKFPTE

Download         Length: 279 bp

>T36485 NZ_AP022810:360500-360778 [Desulfuromonas sp. AOP6]
ATGATTTTTTGGGAAGAAGAATCCTTAAATGATCGAGAGAAAATTTTCGAGTTTCTTTACGTCTTCAACCCAGATGCTGC
TGAAAAAGCAGATGAAATCATTGAAGCTAAAGTTGAAAACTTAATTGAACAACCTTTAATGGGCGTTCAACGGGAGGGAA
TTCGAGGCAGATTGCTCATTATTCCTGAAGTTTCAATGGTCGTATCTTATTTTGTTGACGGATCCACGATTCGCATTCTG
CGAGTTCTTCACCAAAAACAAAAGTTCCCTACCGAGTAG

Antitoxin


Download         Length: 95 a.a.        Molecular weight: 10861.08 Da        Isoelectric Point: 8.0515

>AT36485 WP_155874920.1 NZ_AP022810:360219-360503 [Desulfuromonas sp. AOP6]
MDTRIQFRVDEETKRLAQQRAESQGRTLSDACRELTEQLAEQQRKALSHDTWLTEQVNLAFDKLDSGKAVFVDNDSAKTQ
MAERKAKVRNRGHQ

Download         Length: 285 bp

>AT36485 NZ_AP022810:360219-360503 [Desulfuromonas sp. AOP6]
ATGGATACGAGAATTCAATTTCGTGTTGACGAAGAAACAAAACGCTTAGCCCAGCAAAGGGCTGAAAGCCAAGGTCGCAC
CCTTAGCGACGCTTGCCGAGAACTAACGGAGCAGCTTGCCGAGCAACAACGCAAGGCCTTGTCTCATGATACTTGGCTTA
CCGAACAAGTAAACCTTGCGTTCGACAAACTTGATTCCGGCAAGGCTGTGTTCGTGGACAATGACTCTGCAAAAACACAA
ATGGCTGAACGTAAAGCCAAGGTTCGCAACCGGGGCCACCAATGA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
No matching records found

References