Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE-RelB
Location 360219..360778 Replicon chromosome
Accession NZ_AP022810
Organism Desulfuromonas sp. AOP6

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag AOP6_RS01730 Protein ID WP_155874921.1
Coordinates 360500..360778 (+) Length 93 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag AOP6_RS01725 Protein ID WP_155874920.1
Coordinates 360219..360503 (+) Length 95 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AOP6_RS01690 (AOP6_0344) 355537..356175 - 639 WP_155874913.1 hypothetical protein -
AOP6_RS01695 (AOP6_0345) 356353..356640 - 288 WP_155874914.1 coiled coil domain-containing protein -
AOP6_RS01700 (AOP6_0346) 356735..357043 - 309 WP_155874915.1 ferritin family protein -
AOP6_RS01705 (AOP6_0347) 357386..357736 - 351 WP_213194714.1 DUF1622 domain-containing protein -
AOP6_RS01710 (AOP6_0348) 357975..358757 - 783 WP_155874917.1 MipA/OmpV family protein -
AOP6_RS01715 (AOP6_0349) 358836..359291 - 456 WP_155874918.1 hypothetical protein -
AOP6_RS01720 (AOP6_0350) 359396..359956 - 561 WP_155874919.1 hypothetical protein -
AOP6_RS01725 (AOP6_0351) 360219..360503 + 285 WP_155874920.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
AOP6_RS01730 360500..360778 + 279 WP_155874921.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
AOP6_RS01735 (AOP6_0352) 360901..361608 - 708 WP_155874922.1 hypothetical protein -
AOP6_RS01740 (AOP6_0353) 361756..362052 - 297 WP_155874923.1 hypothetical protein -
AOP6_RS01745 (AOP6_0354) 362124..362879 - 756 WP_155874924.1 hypothetical protein -
AOP6_RS01750 (AOP6_0355) 363515..364078 - 564 WP_155874925.1 hypothetical protein -
AOP6_RS01755 (AOP6_0356) 364175..364669 - 495 WP_155874926.1 hypothetical protein -
AOP6_RS01760 (AOP6_0357) 365163..365474 - 312 WP_155874927.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(2-89)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(5-77)


Sequences

Toxin        


Download         Length: 93 a.a.        Molecular weight: 10797.49 Da        Isoelectric Point: 4.4508

>T36485 WP_155874921.1 NZ_AP022810:360500-360778 [Desulfuromonas sp. AOP6]
MIFWEEESLNDREKIFEFLYVFNPDAAEKADEIIEAKVENLIEQPLMGVQREGIRGRLLIIPEVSMVVSYFVDGSTIRIL
RVLHQKQKFPTE

Download         Length: 279 bp

>T36485 NZ_AP022810:360500-360778 [Desulfuromonas sp. AOP6]
ATGATTTTTTGGGAAGAAGAATCCTTAAATGATCGAGAGAAAATTTTCGAGTTTCTTTACGTCTTCAACCCAGATGCTGC
TGAAAAAGCAGATGAAATCATTGAAGCTAAAGTTGAAAACTTAATTGAACAACCTTTAATGGGCGTTCAACGGGAGGGAA
TTCGAGGCAGATTGCTCATTATTCCTGAAGTTTCAATGGTCGTATCTTATTTTGTTGACGGATCCACGATTCGCATTCTG
CGAGTTCTTCACCAAAAACAAAAGTTCCCTACCGAGTAG

Antitoxin


Download         Length: 95 a.a.        Molecular weight: 10861.08 Da        Isoelectric Point: 8.0515

>AT36485 WP_155874920.1 NZ_AP022810:360219-360503 [Desulfuromonas sp. AOP6]
MDTRIQFRVDEETKRLAQQRAESQGRTLSDACRELTEQLAEQQRKALSHDTWLTEQVNLAFDKLDSGKAVFVDNDSAKTQ
MAERKAKVRNRGHQ

Download         Length: 285 bp

>AT36485 NZ_AP022810:360219-360503 [Desulfuromonas sp. AOP6]
ATGGATACGAGAATTCAATTTCGTGTTGACGAAGAAACAAAACGCTTAGCCCAGCAAAGGGCTGAAAGCCAAGGTCGCAC
CCTTAGCGACGCTTGCCGAGAACTAACGGAGCAGCTTGCCGAGCAACAACGCAAGGCCTTGTCTCATGATACTTGGCTTA
CCGAACAAGTAAACCTTGCGTTCGACAAACTTGATTCCGGCAAGGCTGTGTTCGTGGACAATGACTCTGCAAAAACACAA
ATGGCTGAACGTAAAGCCAAGGTTCGCAACCGGGGCCACCAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References