Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE(toxin)
Location 3705694..3706142 Replicon chromosome
Accession NZ_AP022673
Organism Sphingomonas sp. HMP9

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag HMP09_RS16750 Protein ID WP_176501284.1
Coordinates 3705867..3706142 (+) Length 92 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag HMP09_RS16745 Protein ID WP_176501283.1
Coordinates 3705694..3705870 (+) Length 59 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HMP09_RS16730 3700729..3701172 - 444 WP_176501280.1 hypothetical protein -
HMP09_RS16735 3701328..3704315 + 2988 WP_176501281.1 excinuclease ABC subunit UvrA -
HMP09_RS16740 3704859..3705518 - 660 WP_176501282.1 hypothetical protein -
HMP09_RS16745 3705694..3705870 + 177 WP_176501283.1 stability determinant Antitoxin
HMP09_RS16750 3705867..3706142 + 276 WP_176501284.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
HMP09_RS16755 3706133..3706435 - 303 WP_176501285.1 BrnA antitoxin family protein -
HMP09_RS16760 3706395..3706667 - 273 WP_176501286.1 BrnT family toxin -
HMP09_RS16765 3706833..3707165 + 333 WP_176498641.1 hypothetical protein -
HMP09_RS16770 3707454..3707741 + 288 WP_176501287.1 hypothetical protein -
HMP09_RS16775 3707738..3709222 + 1485 WP_176501288.1 hypothetical protein -
HMP09_RS16780 3709182..3709622 + 441 WP_176501289.1 DUF3597 domain-containing protein -
HMP09_RS16785 3709700..3710113 + 414 WP_176501290.1 glycine zipper 2TM domain-containing protein -
HMP09_RS16790 3710392..3710604 + 213 WP_031394996.1 cold-shock protein -
HMP09_RS16795 3710707..3710937 + 231 WP_176501291.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-90)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 92 a.a.        Molecular weight: 10225.71 Da        Isoelectric Point: 6.4770

>T36484 WP_176501284.1 NZ_AP022673:3705867-3706142 [Sphingomonas sp. HMP9]
MTLPLVWTDDAASDLLNILDYIGARNFAAAERLNAAIVHAAENLPDHPYIYRSGRLAGTREAVVHPNYLLVYRVAETIEI
LAILHARQRYP

Download         Length: 276 bp

>T36484 NZ_AP022673:3705867-3706142 [Sphingomonas sp. HMP9]
TTGACGCTGCCGCTCGTCTGGACGGACGATGCGGCAAGCGACCTACTGAACATTCTCGACTATATTGGCGCGCGGAACTT
CGCGGCCGCGGAGCGGCTGAACGCCGCGATTGTGCATGCGGCGGAGAACCTGCCCGATCATCCTTACATCTACCGCTCCG
GAAGACTGGCCGGAACCCGCGAGGCGGTGGTCCATCCGAACTACCTGCTGGTCTACCGGGTCGCCGAGACGATCGAGATC
CTCGCCATCCTCCACGCCCGCCAGCGTTACCCCTGA

Antitoxin


Download         Length: 59 a.a.        Molecular weight: 6504.30 Da        Isoelectric Point: 4.2840

>AT36484 WP_176501283.1 NZ_AP022673:3705694-3705870 [Sphingomonas sp. HMP9]
MSELNPIESEFATSEDAAAYDAWFRAKVERAMTSDAPSIPHAEVMAMAQDILDKYKPR

Download         Length: 177 bp

>AT36484 NZ_AP022673:3705694-3705870 [Sphingomonas sp. HMP9]
ATGTCGGAGCTAAACCCCATCGAGTCGGAGTTCGCGACCAGTGAGGATGCCGCCGCGTACGACGCGTGGTTCCGCGCCAA
GGTCGAGCGTGCGATGACGTCGGATGCACCCAGCATTCCACACGCTGAAGTGATGGCAATGGCGCAGGATATCCTCGACA
AATACAAGCCGCGTTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References