36446

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) /Acetyltransf_4(toxin)
Location 1729765..1731173 Replicon chromosome
Accession NZ_AP022642
Organism Pseudomonas otitidis strain MrB4

Toxin (Protein)


Gene name - Uniprot ID -
Locus tag PotMrB4_RS08125 Protein ID WP_172432978.1
Coordinates 1729765..1730334 (+) Length 190 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID -
Locus tag PotMrB4_RS08130 Protein ID WP_172432979.1
Coordinates 1730331..1731173 (+) Length 281 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PotMrB4_RS08115 1724765..1725964 - 1200 WP_172432976.1 GGDEF domain-containing protein -
PotMrB4_RS08120 1726053..1729529 - 3477 WP_172432977.1 hybrid sensor histidine kinase/response regulator -
PotMrB4_RS08125 1729765..1730334 + 570 WP_172432978.1 GNAT family N-acetyltransferase Toxin
PotMrB4_RS08130 1730331..1731173 + 843 WP_172432979.1 AraC family transcriptional regulator Antitoxin
PotMrB4_RS08135 1731211..1731924 + 714 WP_142011212.1 AzlC family ABC transporter permease -
PotMrB4_RS08140 1731924..1732253 + 330 WP_172432980.1 AzlD domain-containing protein -
PotMrB4_RS08145 1732384..1734258 + 1875 WP_172432981.1 MFS transporter -
PotMrB4_RS08150 1734312..1734626 - 315 WP_044406178.1 quaternary ammonium compound efflux SMR transporter SugE -
PotMrB4_RS08155 1734790..1735743 - 954 WP_107330404.1 bile acid:sodium symporter family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(14-146)

Antitoxin

AraC-type arabinose-binding/dimerisation domain

(18-149)


Sequences

Toxin        


Download         Length: 190 a.a.        Molecular weight: 21156.18 Da        Isoelectric Point: 7.4702

>T36446 WP_172432978.1 NZ_AP022642:1729765-1730334 [Pseudomonas otitidis]
MFNPQPVTLQRGALRLEPLGEADVSELAALAEANRNELVYMSGPLRPDWYRQGIAQQREGQAVVFAIRLGDRLVGTSRFA
EFMPALPAVEIGWTWLAGSEHGTGLNASIKYLMLRHAFEEWHVVRVQLKTAGSNLRSQRAIEKLGAVREGVLRNHRRLAD
GRLDDSVMFSITDHEWPAVKQALEAAFVQ

Download         Length: 570 bp

>T36446 NZ_AP022642:1729765-1730334 [Pseudomonas otitidis]
ATGTTCAATCCGCAACCGGTCACCCTGCAGCGTGGCGCATTGCGCCTGGAGCCACTGGGGGAGGCCGATGTCAGCGAGCT
GGCGGCCCTGGCCGAAGCCAATCGCAACGAACTGGTCTACATGAGCGGCCCGCTGCGGCCGGACTGGTACCGGCAGGGCA
TCGCCCAGCAGCGCGAAGGCCAGGCCGTGGTGTTCGCCATCCGCCTGGGTGACCGCCTGGTGGGCACCAGCCGATTCGCC
GAATTCATGCCGGCCCTGCCCGCCGTGGAGATCGGCTGGACCTGGCTGGCCGGCAGCGAGCACGGCACTGGCCTCAACGC
CTCGATCAAGTACCTGATGCTGCGCCACGCCTTCGAGGAGTGGCATGTGGTGCGGGTGCAGCTGAAGACCGCCGGCAGCA
ACCTGCGCTCGCAACGGGCCATCGAGAAGCTTGGCGCGGTGCGTGAGGGTGTGCTGCGCAACCACCGTCGCCTGGCCGAC
GGGCGCCTGGACGACAGCGTCATGTTCAGCATCACGGACCACGAGTGGCCGGCGGTGAAGCAGGCACTGGAAGCTGCATT
CGTCCAATGA

Antitoxin


Download         Length: 281 a.a.        Molecular weight: 31323.62 Da        Isoelectric Point: 9.0216

>AT36446 WP_172432979.1 NZ_AP022642:1730331-1731173 [Pseudomonas otitidis]
MSTGGERTRFWQASALSGVELLHARYIQHRFSPHVHEGYVFTILESGAQRFRHRGSDHLAAVGSMVLINPDELHTGSKAH
EEGWRYRGFYPDLHRVTDVLDELEIATGGLPTFADSVLHDPEVTRRFLDLHCLLERNASALEQQVAWREAILLLFSRHAR
IGAPRPAGQEPQAVALAREMMAARLASPPSLEELAALVGLSPFHFARVFQRATGMPPHAWLKQRRLEQARAMLRSGCAPL
SVAMQLGFADQSHLTRQFKQTYGVGPGEYRTASARSFKTD

Download         Length: 843 bp

>AT36446 NZ_AP022642:1730331-1731173 [Pseudomonas otitidis]
ATGAGCACGGGGGGTGAGCGCACCCGCTTCTGGCAGGCCAGTGCGCTGAGCGGGGTCGAGCTCCTGCATGCGCGCTACAT
CCAGCATCGCTTCTCGCCCCACGTGCACGAAGGCTACGTCTTCACCATCCTCGAGTCCGGCGCCCAGCGCTTCCGCCATC
GCGGCAGCGACCACCTGGCCGCCGTCGGCAGCATGGTGCTGATCAACCCGGACGAGCTGCACACCGGCTCCAAGGCCCAC
GAGGAAGGCTGGCGCTACCGGGGGTTCTACCCCGACCTGCACCGGGTGACCGATGTGCTGGACGAGCTGGAGATCGCCAC
CGGTGGCCTGCCCACCTTCGCCGACAGCGTGCTGCATGACCCCGAGGTGACCCGCCGCTTCCTCGACCTGCACTGCCTGC
TGGAGCGCAATGCCTCCGCCCTGGAGCAGCAGGTGGCCTGGCGCGAGGCGATCCTGCTGCTGTTCAGCCGCCACGCGCGC
ATCGGTGCGCCACGGCCGGCGGGGCAGGAGCCCCAGGCCGTGGCGCTGGCCCGCGAGATGATGGCGGCGCGCCTGGCCTC
GCCGCCATCCCTGGAGGAACTGGCGGCCCTGGTGGGGCTTTCGCCGTTCCACTTCGCCCGGGTCTTCCAGCGCGCCACCG
GGATGCCGCCCCACGCGTGGCTCAAGCAGCGTCGCCTGGAGCAGGCGCGGGCCATGCTGCGCAGCGGTTGCGCGCCGTTG
TCGGTGGCGATGCAGCTGGGCTTTGCCGACCAGAGCCACCTGACCCGTCAGTTCAAGCAGACCTACGGGGTAGGTCCCGG
CGAATACCGGACCGCCAGCGCAAGATCGTTCAAGACCGACTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References