Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VapB
Location 1569013..1569614 Replicon chromosome
Accession NZ_AP022616
Organism Mycolicibacterium phocaicum strain JCM 15301

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag G6N46_RS07615 Protein ID WP_133425924.1
Coordinates 1569213..1569614 (+) Length 134 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag G6N46_RS07610 Protein ID WP_133425925.1
Coordinates 1569013..1569216 (+) Length 68 a.a.

Genomic Context

G6N46_RS07595G6N46_RS07600G6N46_RS07605G6N46_RS07610G6N46_RS07615G6N46_RS07620G6N46_RS07625
Location: 1564303..1565583 (1281 bp)
Type: Others
Protein ID: WP_138248770.1
Location: 1565580..1567667 (2088 bp)
Type: Others
Protein ID: WP_138248769.1
Location: 1567850..1568365 (516 bp)
Type: Others
Protein ID: WP_138248768.1
Location: 1569013..1569216 (204 bp)
Type: Antitoxin
Protein ID: WP_133425925.1
Location: 1569213..1569614 (402 bp)
Type: Toxin
Protein ID: WP_133425924.1
Location: 1569597..1570736 (1140 bp)
Type: Others
Protein ID: WP_138248767.1
Location: 1570729..1574007 (3279 bp)
Type: Others
Protein ID: WP_061001013.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
G6N46_RS075951564303..1565583+1281WP_138248770.1BREX system ATP-binding protein BrxD-
G6N46_RS076001565580..1567667+2088WP_138248769.1DEAD/DEAH box helicase-
G6N46_RS076051567850..1568365+516WP_138248768.1RNA methyltransferase-
G6N46_RS076101569013..1569216+204WP_133425925.1type II toxin-antitoxin system VapB family antitoxinAntitoxin
G6N46_RS076151569213..1569614+402WP_133425924.1PIN domain nucleaseToxin
G6N46_RS076201569597..1570736-1140WP_138248767.1hypothetical protein-
G6N46_RS076251570729..1574007-3279WP_061001013.1AAA family ATPase-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(2-120)

Antitoxin

Bacterial antitoxin of type II TA system, VapB

(3-41)


Sequences

Toxin        


Download         Length: 134 a.a.        Molecular weight: 14814.98 Da        Isoelectric Point: 6.0803

>T36395 WP_133425924.1 NZ_AP022616:1569213-1569614 [Mycolicibacterium phocaicum]
MILVDTSAWIEFLRNTGSGVCVRVDELLAEPIAICAPVQMEILAGARNDRHLKDLRGLLARAQTLPTSPTDYEDAATIYR
VCRRRGETVRRLIDCLIAAHAIREQIPILHSDGDFDAIARHTSLQLDTSPRPD

Download         Length: 402 bp

>T36395 NZ_AP022616:1569213-1569614 [Mycolicibacterium phocaicum]
ATGATCCTCGTTGACACGTCAGCCTGGATCGAGTTTCTAAGGAACACCGGGAGCGGTGTGTGCGTGCGAGTCGACGAGCT
ACTCGCCGAGCCGATCGCGATCTGCGCTCCCGTCCAGATGGAAATCCTCGCCGGGGCCCGAAACGACCGCCACCTCAAGG
ATCTTCGTGGCCTGTTGGCACGCGCACAAACTCTACCGACATCCCCCACTGACTATGAAGACGCCGCAACCATTTACCGC
GTCTGTCGGCGTCGCGGTGAAACCGTACGCAGGCTGATCGACTGCCTCATCGCCGCGCACGCCATACGCGAACAGATTCC
AATCCTGCACTCCGACGGCGACTTCGACGCAATTGCGCGGCATACATCACTACAGCTGGATACCTCACCGCGGCCGGACT
GA

Antitoxin


Download         Length: 68 a.a.        Molecular weight: 7754.72 Da        Isoelectric Point: 6.4577

>AT36395 WP_133425925.1 NZ_AP022616:1569013-1569216 [Mycolicibacterium phocaicum]
MTRTNIDIDDHACEVVMRRFHLTSKRDAVNFALRNLAQEALDLKAARELRGSGWDADLDELRSDRVR

Download         Length: 204 bp

>AT36395 NZ_AP022616:1569013-1569216 [Mycolicibacterium phocaicum]
ATGACCCGCACAAACATCGACATCGACGACCATGCGTGCGAGGTCGTCATGCGAAGGTTCCATTTGACCAGCAAGCGAGA
CGCGGTGAACTTCGCGTTGCGCAATCTCGCCCAGGAAGCATTGGACCTCAAAGCGGCCCGAGAACTCCGCGGGTCCGGAT
GGGACGCCGATCTCGATGAATTGCGCAGCGACCGCGTCCGATGA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
No matching records found

References