Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) phd-doc/Fic(toxin)
Location 3968029..3968612 Replicon chromosome
Accession NZ_AP022603
Organism Mycolicibacterium fallax strain JCM 6405

Toxin (Protein)


Gene name doc Uniprot ID -
Locus tag G6N10_RS19110 Protein ID WP_085099989.1
Coordinates 3968223..3968612 (+) Length 130 a.a.

Antitoxin (Protein)


Gene name phd Uniprot ID -
Locus tag G6N10_RS19105 Protein ID WP_085099992.1
Coordinates 3968029..3968226 (+) Length 66 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
G6N10_RS19090 3963458..3963724 - 267 WP_085100001.1 hypothetical protein -
G6N10_RS19095 3963780..3965525 - 1746 WP_085099998.1 BCCT family transporter -
G6N10_RS20085 3965621..3965788 - 168 WP_165757684.1 hypothetical protein -
G6N10_RS19100 3965841..3967742 + 1902 WP_085099995.1 translational GTPase TypA -
G6N10_RS19105 3968029..3968226 + 198 WP_085099992.1 antitoxin Phd Antitoxin
G6N10_RS19110 3968223..3968612 + 390 WP_085099989.1 type II toxin-antitoxin system death-on-curing family toxin Toxin
G6N10_RS19115 3968650..3968880 - 231 WP_163742598.1 hypothetical protein -
G6N10_RS20145 3969380..3969799 - 420 WP_179962856.1 hypothetical protein -
G6N10_RS19125 3970591..3972468 + 1878 WP_179962906.1 ABC transporter family substrate-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Fido domain

(28-83)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 130 a.a.        Molecular weight: 13738.36 Da        Isoelectric Point: 4.1564

>T36308 WP_085099989.1 NZ_AP022603:3968223-3968612 [Mycolicibacterium fallax]
MTVFLDREDVLTAGAFAVGHGPEVGDYGLLDAAVARPQASVFGVDAYPGRYAKAAALLQSLARNHALVDGNKRTAWAAAW
TFLHINGIELRPDFDVDAAEDLMNDVATNGDLTVEFIAERLVGFGADCD

Download         Length: 390 bp

>T36308 NZ_AP022603:3968223-3968612 [Mycolicibacterium fallax]
ATGACCGTTTTTCTCGATCGCGAGGATGTTCTTACGGCCGGGGCTTTCGCGGTCGGTCATGGGCCGGAGGTGGGTGACTA
CGGCCTGTTGGACGCCGCCGTCGCACGCCCGCAGGCCAGTGTCTTCGGTGTTGATGCGTACCCGGGGCGGTATGCCAAGG
CGGCGGCGCTGCTGCAGTCGCTGGCCCGCAATCATGCGCTGGTCGATGGGAACAAGCGCACCGCATGGGCGGCGGCATGG
ACGTTCCTGCATATCAATGGCATCGAGTTGCGTCCGGATTTCGATGTCGACGCGGCCGAGGACCTGATGAACGATGTCGC
CACCAACGGCGACCTGACGGTCGAGTTCATTGCCGAGCGGCTGGTTGGGTTCGGCGCCGACTGCGACTGA

Antitoxin


Download         Length: 66 a.a.        Molecular weight: 6873.73 Da        Isoelectric Point: 6.4563

>AT36308 WP_085099992.1 NZ_AP022603:3968029-3968226 [Mycolicibacterium fallax]
MPSLNISFTDDELAAVRAAAGEVDVSLRTFAHDAVVAAASRHKQAVADAARLVAERSAELNRRLA

Download         Length: 198 bp

>AT36308 NZ_AP022603:3968029-3968226 [Mycolicibacterium fallax]
ATGCCCTCGCTGAACATCTCCTTCACCGACGACGAACTCGCGGCCGTCCGTGCTGCCGCCGGGGAGGTCGATGTGTCGTT
GCGGACTTTTGCGCACGACGCGGTGGTCGCCGCAGCGAGCCGGCACAAGCAGGCGGTGGCTGACGCGGCGCGTCTGGTGG
CGGAGCGTTCGGCGGAGCTGAACCGACGGCTGGCATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References