Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YoeB-YefM
Location 355119..355651 Replicon chromosome
Accession NZ_AP022603
Organism Mycolicibacterium fallax strain JCM 6405

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag G6N10_RS01680 Protein ID WP_085093841.1
Coordinates 355394..355651 (+) Length 86 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag G6N10_RS01675 Protein ID WP_085093919.1
Coordinates 355119..355397 (+) Length 93 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
G6N10_RS01655 352192..352770 - 579 WP_085093916.1 ferritin-like domain-containing protein -
G6N10_RS01660 352794..353309 - 516 WP_085093917.1 hypothetical protein -
G6N10_RS01665 353497..354045 + 549 WP_085093836.1 ribosome maturation factor RimP -
G6N10_RS01670 354042..355040 + 999 WP_085093839.1 transcription termination/antitermination protein NusA -
G6N10_RS01675 355119..355397 + 279 WP_085093919.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
G6N10_RS01680 355394..355651 + 258 WP_085093841.1 Txe/YoeB family addiction module toxin Toxin
G6N10_RS01685 355747..356103 + 357 WP_085093843.1 DUF448 domain-containing protein -
G6N10_RS01690 356183..358916 + 2734 Protein_330 translation initiation factor IF-2 -
G6N10_RS01695 358947..359453 + 507 WP_085094469.1 30S ribosome-binding factor RbfA -
G6N10_RS01700 359428..360432 + 1005 WP_085094467.1 bifunctional oligoribonuclease/PAP phosphatase NrnA -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(4-85)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(2-71)


Sequences

Toxin        


Download         Length: 86 a.a.        Molecular weight: 10162.54 Da        Isoelectric Point: 8.5036

>T36301 WP_085093841.1 NZ_AP022603:355394-355651 [Mycolicibacterium fallax]
VSSLHFDRDAWEDFLFWLASDRKMARRIARLIAEIQRDPFAGIGKPEPLRGELSGYWSRRIDDEHRLVYRADDAEVKILK
ARYHY

Download         Length: 258 bp

>T36301 NZ_AP022603:355394-355651 [Mycolicibacterium fallax]
GTGAGCAGCCTCCACTTCGACCGCGATGCCTGGGAGGACTTCCTGTTCTGGCTGGCATCCGATCGCAAGATGGCCCGCCG
GATCGCCCGGCTGATCGCCGAGATCCAGCGCGACCCGTTCGCCGGGATCGGTAAGCCGGAACCGCTCAGGGGCGAGTTGT
CGGGCTACTGGTCGCGGCGCATCGACGATGAGCACCGCCTGGTCTACCGGGCCGACGACGCCGAGGTGAAGATTCTCAAG
GCCCGCTACCACTACTGA

Antitoxin


Download         Length: 93 a.a.        Molecular weight: 10302.48 Da        Isoelectric Point: 4.6677

>AT36301 WP_085093919.1 NZ_AP022603:355119-355397 [Mycolicibacterium fallax]
VSISASEARQRLFPLLEQVNTDHEPVRITSKAGDAVLMSADDFDSWQETVYLLRSPENARRLMEAVARDRARPSDSRAVT
IEELRSMAGGQE

Download         Length: 279 bp

>AT36301 NZ_AP022603:355119-355397 [Mycolicibacterium fallax]
GTGAGCATCAGTGCCAGTGAGGCGCGCCAGCGACTGTTCCCGCTGTTGGAGCAGGTCAACACCGACCATGAGCCGGTACG
GATCACGTCCAAGGCCGGCGACGCCGTCTTGATGTCCGCCGACGATTTCGATTCGTGGCAGGAGACGGTGTACCTGCTGC
GGTCTCCGGAGAACGCCCGCCGCCTGATGGAGGCGGTGGCCAGGGACCGGGCCCGCCCGTCGGATTCGCGCGCGGTGACG
ATCGAGGAGCTGAGGAGCATGGCCGGCGGGCAGGAGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References