Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) unclassified/Polyketide_cyc2(toxin)
Location 3297548..3298204 Replicon chromosome
Accession NZ_AP022596
Organism Mycolicibacterium helvum strain JCM 30396

Toxin (Protein)


Gene name novel[antitoxin] Uniprot ID -
Locus tag G6N38_RS15530 Protein ID WP_163748909.1
Coordinates 3297758..3298204 (+) Length 149 a.a.

Antitoxin (Protein)


Gene name novel[toxin] Uniprot ID -
Locus tag G6N38_RS15525 Protein ID WP_163748906.1
Coordinates 3297548..3297754 (+) Length 69 a.a.

Genomic Context

G6N38_RS15515G6N38_RS15520G6N38_RS15525G6N38_RS15530G6N38_RS15540G6N38_RS15555G6N38_RS15535G6N38_RS15545G6N38_RS15550G6N38_RS15560
Location: 3293562..3295148 (1587 bp)
Type: Others
Protein ID: WP_163748902.1
Location: 3295145..3297544 (2400 bp)
Type: Others
Protein ID: WP_163748904.1
Location: 3297548..3297754 (207 bp)
Type: Antitoxin
Protein ID: WP_163748906.1
Location: 3297758..3298204 (447 bp)
Type: Toxin
Protein ID: WP_163748909.1
Location: 3298744..3298971 (228 bp)
Type: Others
Protein ID: WP_163748913.1
Location: 3301395..3302282 (888 bp)
Type: Others
Protein ID: WP_163748919.1
Location: 3298219..3298602 (384 bp)
Type: Others
Protein ID: WP_163748910.1
Location: 3298968..3300533 (1566 bp)
Type: Others
Protein ID: WP_163748915.1
Location: 3300526..3301167 (642 bp)
Type: Others
Protein ID: WP_163748917.1
Location: 3302279..3303166 (888 bp)
Type: Others
Protein ID: WP_163748921.1
ToxinAntitoxinOther genes
Loading, please wait
Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
G6N38_RS155153293562..3295148+1587WP_163748902.1serine hydrolase-
G6N38_RS155203295145..3297544+2400WP_163748904.1HAD-IC family P-type ATPase-
G6N38_RS155253297548..3297754+207WP_163748906.1antitoxinAntitoxin
G6N38_RS155303297758..3298204+447WP_163748909.1SRPBCC family proteinToxin
G6N38_RS155353298219..3298602-384WP_163748910.1hypothetical protein-
G6N38_RS155403298744..3298971+228WP_163748913.1hypothetical protein-
G6N38_RS155453298968..3300533-1566WP_163748915.1GAF domain-containing protein-
G6N38_RS155503300526..3301167-642WP_163748917.1response regulator transcription factor-
G6N38_RS155553301395..3302282+888WP_163748919.1amidohydrolase family protein-
G6N38_RS155603302279..3303166-888WP_163748921.1hypothetical protein-

Associated MGEs

Loading, please wait
MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Polyketide cyclase/dehydrase

(1-145)

Antitoxin

Antitoxin Rv0909/MT0933

(8-54)


Sequences

Toxin        


Download         Length: 149 a.a.        Molecular weight: 15911.56 Da        Isoelectric Point: 10.2881

>T36287 WP_163748909.1 NZ_AP022596:3297758-3298204 [Mycolicibacterium helvum]
MAKLSVSVDVPLPPEQAWQHASDLSRYKDWLTIHRVWRSTLPDTLDKGTVVESIVEVKGMPNRVKWTIVHFKAPEAMTLN
GVGVGGVKVKLIGKVRASASDANASVVTMDVHLGGPALFGPIGMIVAGALRGDIKESLNRFVTVFAPS

Download         Length: 447 bp

>T36287 NZ_AP022596:3297758-3298204 [Mycolicibacterium helvum]
ATGGCGAAACTCTCAGTATCTGTCGACGTTCCACTCCCACCCGAGCAAGCCTGGCAGCACGCCTCGGACCTGTCGCGCTA
TAAGGATTGGCTGACCATCCACCGGGTCTGGCGCTCCACACTGCCCGACACTCTGGACAAGGGCACGGTTGTGGAGTCCA
TCGTCGAGGTCAAGGGCATGCCCAACCGGGTGAAGTGGACGATCGTCCATTTCAAGGCGCCGGAGGCGATGACACTCAAT
GGTGTCGGCGTCGGCGGGGTCAAGGTCAAGCTGATCGGCAAGGTCCGGGCGAGCGCCTCGGACGCGAACGCCTCGGTGGT
GACTATGGACGTCCATCTGGGTGGTCCGGCGCTGTTCGGGCCCATCGGCATGATCGTGGCCGGGGCGCTGCGTGGCGACA
TCAAGGAGTCGCTGAACCGGTTCGTGACGGTCTTCGCTCCGTCCTAG

Antitoxin


Download         Length: 69 a.a.        Molecular weight: 7439.29 Da        Isoelectric Point: 4.6050

>AT36287 WP_163748906.1 NZ_AP022596:3297548-3297754 [Mycolicibacterium helvum]
MGFLDKALDKTKEVLSENADKVGQAIDKAGDIIDEKTQGKYASTVDKVQDAAKNIVEKNRTEKGDEQV

Download         Length: 207 bp

>AT36287 NZ_AP022596:3297548-3297754 [Mycolicibacterium helvum]
ATGGGATTCCTCGATAAAGCCCTCGACAAGACCAAAGAAGTCCTGAGCGAGAATGCCGACAAGGTGGGGCAGGCCATCGA
CAAGGCCGGTGACATCATCGACGAGAAGACACAGGGCAAGTACGCCAGCACCGTGGACAAGGTGCAGGACGCCGCGAAGA
ACATCGTCGAGAAGAACCGCACCGAAAAGGGCGACGAACAAGTCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Loading, please wait
Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
Loading, please wait
Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

Loading, please wait
Source
ID
Structure
No matching records found

Antitoxin

Loading, please wait
Source
ID
Structure
No matching records found

References