Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC(toxin)
Location 166636..167273 Replicon chromosome
Accession NZ_AP022595
Organism Mycolicibacterium sarraceniae strain JCM 30395

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag G6N13_RS00950 Protein ID WP_163694432.1
Coordinates 166636..167055 (-) Length 140 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag G6N13_RS00955 Protein ID WP_163694433.1
Coordinates 167052..167273 (-) Length 74 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
G6N13_RS00915 161646..162626 - 981 WP_163694426.1 hypothetical protein -
G6N13_RS00920 162733..163455 - 723 WP_163694427.1 hypothetical protein -
G6N13_RS00925 163556..163768 - 213 WP_163694428.1 hypothetical protein -
G6N13_RS00930 163765..164091 - 327 WP_163694429.1 hypothetical protein -
G6N13_RS24040 164437..164985 - 549 Protein_184 hypothetical protein -
G6N13_RS00940 165270..165722 - 453 WP_163694431.1 hypothetical protein -
G6N13_RS24425 166120..166446 - 327 WP_197746819.1 hypothetical protein -
G6N13_RS00950 166636..167055 - 420 WP_163694432.1 PIN domain nuclease Toxin
G6N13_RS00955 167052..167273 - 222 WP_163694433.1 antitoxin Antitoxin
G6N13_RS00965 168096..168305 + 210 Protein_189 TetR family transcriptional regulator -
G6N13_RS00975 168529..169485 - 957 WP_163694434.1 formyltetrahydrofolate deformylase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(7-124)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 140 a.a.        Molecular weight: 15438.64 Da        Isoelectric Point: 5.2050

>T36279 WP_163694432.1 NZ_AP022595:c167055-166636 [Mycolicibacterium sarraceniae]
MTERPWLIDKSALVRVADSADVDEWNNRIERGLVHITNVTRLEIGYSARSGAGARRDFRQPPLCAMPVEYLTPAIEDRAL
EVQLLLADIGQHRGPSIPDLLIAATAELVGLTVLHVDRDFDVISELTGQPTHRLTVPPR

Download         Length: 420 bp

>T36279 NZ_AP022595:c167055-166636 [Mycolicibacterium sarraceniae]
ATGACCGAACGGCCCTGGCTGATCGACAAGTCGGCGCTAGTGCGAGTCGCCGATAGTGCTGACGTTGACGAGTGGAACAA
CCGCATCGAACGGGGTCTGGTGCACATCACGAATGTCACCCGCCTGGAGATCGGTTACTCCGCGCGCAGCGGCGCGGGCG
CCCGTCGCGACTTTCGTCAACCCCCGCTCTGCGCAATGCCCGTCGAGTATCTAACGCCGGCGATCGAGGATCGCGCGTTG
GAGGTTCAGTTGCTGCTCGCTGATATCGGCCAGCACCGCGGGCCGTCGATTCCAGATTTACTGATCGCAGCAACCGCCGA
GCTCGTCGGGCTCACCGTGTTGCACGTCGATAGGGATTTCGATGTGATCAGTGAACTCACCGGGCAACCGACCCATCGTT
TGACTGTCCCGCCACGCTGA

Antitoxin


Download         Length: 74 a.a.        Molecular weight: 8144.23 Da        Isoelectric Point: 4.9484

>AT36279 WP_163694433.1 NZ_AP022595:c167273-167052 [Mycolicibacterium sarraceniae]
MSDVLIRDIPDDVLVALDQLAVKLGLSRTEYIRRRLAQDARTASIAVTTGDWHRFAASYGDLGNPAVMDRAWE

Download         Length: 222 bp

>AT36279 NZ_AP022595:c167273-167052 [Mycolicibacterium sarraceniae]
ATGAGCGACGTCCTGATACGGGACATCCCCGACGATGTCCTGGTTGCGTTAGACCAGCTCGCTGTAAAACTGGGGCTTTC
CCGCACCGAGTACATTCGCCGGCGGCTAGCCCAGGACGCACGCACGGCGAGTATCGCCGTCACTACCGGTGACTGGCACC
GATTCGCAGCCTCCTACGGCGACCTCGGCAACCCGGCTGTGATGGACCGGGCCTGGGAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References