Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tacAT/DUF1778(antitoxin)
Location 1846195..1847037 Replicon chromosome
Accession NZ_AP022594
Organism Mycolicibacillus koreensis strain JCM 19956

Toxin (Protein)


Gene name tacT Uniprot ID -
Locus tag G6N11_RS09305 Protein ID WP_197747592.1
Coordinates 1846195..1846728 (-) Length 178 a.a.

Antitoxin (Protein)


Gene name tacA Uniprot ID -
Locus tag G6N11_RS09310 Protein ID WP_069392258.1
Coordinates 1846735..1847037 (-) Length 101 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
G6N11_RS09285 1841205..1841756 + 552 WP_069392220.1 RDD family protein -
G6N11_RS09290 1841769..1843241 - 1473 WP_133056077.1 hypothetical protein -
G6N11_RS09295 1843260..1845458 - 2199 WP_133056078.1 hypothetical protein -
G6N11_RS09300 1845797..1846066 + 270 WP_085303367.1 hypothetical protein -
G6N11_RS09305 1846195..1846728 - 534 WP_197747592.1 GNAT family N-acetyltransferase Toxin
G6N11_RS09310 1846735..1847037 - 303 WP_069392258.1 DUF1778 domain-containing protein Antitoxin
G6N11_RS09320 1847472..1848644 + 1173 WP_085303368.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(35-146)

Antitoxin

Vibrio phage ICP1, Orf50

(16-92)


Sequences

Toxin        


Download         Length: 178 a.a.        Molecular weight: 19118.85 Da        Isoelectric Point: 9.0230

>T36277 WP_197747592.1 NZ_AP022594:c1846728-1846195 [Mycolicibacillus koreensis]
VTSGSKSSARKPKPPQKLTSEHDRTGFSSGAAELDEWLAKYSWQNQRANNATTYVSIFEGRVVGYYAITVAGIARSEAPE
AIAKRAPATVPCFLLARLAVDVEWQGCGLGWGLLRDVLRRVLQLSESVAAPALLVHARDDAARAFYLHHAEFLPSPIDPL
HLLLPTKAIAAAIGGNF

Download         Length: 534 bp

>T36277 NZ_AP022594:c1846728-1846195 [Mycolicibacillus koreensis]
GTGACTAGCGGCTCTAAGAGCAGTGCGCGCAAGCCGAAGCCACCACAGAAACTGACCAGCGAGCACGACCGGACCGGATT
CTCCTCCGGCGCCGCCGAGCTGGACGAATGGCTAGCGAAGTACAGCTGGCAGAATCAGCGAGCCAACAACGCGACCACCT
ACGTGAGCATCTTCGAGGGCCGGGTTGTCGGTTACTACGCCATCACCGTTGCTGGTATCGCGCGTAGCGAAGCCCCTGAA
GCGATCGCCAAACGCGCACCCGCGACGGTGCCGTGTTTCCTGCTGGCCAGACTGGCGGTAGATGTCGAATGGCAGGGCTG
CGGTCTCGGGTGGGGTCTGTTGCGTGATGTGCTGCGCCGAGTCCTGCAACTTTCGGAGTCTGTGGCAGCTCCAGCGCTGC
TCGTTCACGCCCGCGACGACGCTGCTCGGGCGTTCTACCTGCACCATGCCGAATTCCTGCCCTCGCCGATCGACCCGTTG
CATCTGCTCTTGCCGACCAAGGCCATCGCAGCAGCGATCGGCGGGAATTTTTAG

Antitoxin


Download         Length: 101 a.a.        Molecular weight: 11609.03 Da        Isoelectric Point: 4.7037

>AT36277 WP_069392258.1 NZ_AP022594:c1847037-1846735 [Mycolicibacillus koreensis]
MSNVHGPSTKATRDQRLNFRASAQQQLLIRQAAEAADRTVTDFILDSVLESAERILADRKWFVANDEQWERFQELLDAPL
QPMPKLRQLLQRESPFAEEE

Download         Length: 303 bp

>AT36277 NZ_AP022594:c1847037-1846735 [Mycolicibacillus koreensis]
ATGAGCAACGTCCACGGTCCGTCCACTAAAGCCACCCGTGATCAGCGACTGAACTTCAGGGCCAGCGCTCAACAGCAGCT
GTTGATCCGACAGGCTGCTGAAGCCGCCGACCGTACTGTCACCGACTTCATCCTGGACAGCGTTCTGGAAAGTGCCGAGC
GGATACTCGCCGACCGCAAGTGGTTTGTGGCTAACGATGAGCAATGGGAGCGGTTCCAGGAACTCCTGGATGCGCCGCTG
CAGCCCATGCCGAAGCTGCGGCAGCTACTGCAGCGTGAAAGCCCATTCGCAGAAGAGGAGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References