Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) unclassified/Polyketide_cyc2(toxin)
Location 4931571..4932236 Replicon chromosome
Accession NZ_AP022587
Organism Mycobacterium stomatepiae strain JCM 17783

Toxin (Protein)


Gene name novel[antitoxin] Uniprot ID -
Locus tag G6N54_RS23560 Protein ID WP_163792497.1
Coordinates 4931763..4932236 (+) Length 158 a.a.

Antitoxin (Protein)


Gene name novel[toxin] Uniprot ID -
Locus tag G6N54_RS23555 Protein ID WP_163792496.1
Coordinates 4931571..4931759 (+) Length 63 a.a.

Genomic Context

G6N54_RS23545G6N54_RS23550G6N54_RS23555G6N54_RS23560G6N54_RS23565G6N54_RS23570G6N54_RS23540G6N54_RS23575G6N54_RS23580G6N54_RS23585
Location: 4927491..4929071 (1581 bp)
Type: Others
Protein ID: WP_163792494.1
Location: 4929068..4931467 (2400 bp)
Type: Others
Protein ID: WP_163792495.1
Location: 4931571..4931759 (189 bp)
Type: Antitoxin
Protein ID: WP_163792496.1
Location: 4931763..4932236 (474 bp)
Type: Toxin
Protein ID: WP_163792497.1
Location: 4932275..4932424 (150 bp)
Type: Others
Protein ID: Protein_4682
Location: 4932567..4933001 (435 bp)
Type: Others
Protein ID: WP_163792499.1
Location: 4926907..4927446 (540 bp)
Type: Others
Protein ID: WP_197939554.1
Location: 4933006..4933491 (486 bp)
Type: Others
Protein ID: WP_163792501.1
Location: 4933529..4935043 (1515 bp)
Type: Others
Protein ID: WP_163792503.1
Location: 4935045..4936271 (1227 bp)
Type: Others
Protein ID: WP_163792505.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
G6N54_RS235404926907..4927446-540WP_197939554.1G/U mismatch-specific DNA glycosylase-
G6N54_RS235454927491..4929071+1581WP_163792494.1serine hydrolase-
G6N54_RS235504929068..4931467+2400WP_163792495.1cation-translocating P-type ATPase-
G6N54_RS235554931571..4931759+189WP_163792496.1antitoxinAntitoxin
G6N54_RS235604931763..4932236+474WP_163792497.1SRPBCC family proteinToxin
G6N54_RS235654932275..4932424+150Protein_4682VOC family protein-
G6N54_RS235704932567..4933001+435WP_163792499.1hypothetical protein-
G6N54_RS235754933006..4933491-486WP_163792501.1VOC family protein-
G6N54_RS235804933529..4935043-1515WP_163792503.1carotenoid oxygenase family protein-
G6N54_RS235854935045..4936271-1227WP_163792505.1acetyl-CoA acetyltransferase-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Polyketide cyclase/dehydrase

(1-142)

Antitoxin

Antitoxin Rv0909/MT0933

(4-52)


Sequences

Toxin        


Download         Length: 158 a.a.        Molecular weight: 17003.68 Da        Isoelectric Point: 9.5659

>T36261 WP_163792497.1 NZ_AP022587:4931763-4932236 [Mycobacterium stomatepiae]
MAKLSGAIDVPLSPEQAWTHASDLSRYKDWLSIHRVWRSQLPDNLEKGTVIESIVEVKGMLNRIKWTIVHYKPPEAMTLN
GVGVGGVKVKLIAKVKPNDAGSIVSFDVHLGGPALFGPIGMIVAAALRSDIDESLERFVTVFTAPDPGRNGHGITGR

Download         Length: 474 bp

>T36261 NZ_AP022587:4931763-4932236 [Mycobacterium stomatepiae]
ATGGCGAAACTTTCCGGAGCCATCGACGTACCGCTGTCGCCCGAGCAGGCCTGGACGCATGCCTCCGATCTGTCCCGCTA
CAAGGACTGGCTGAGCATCCACCGGGTGTGGCGCAGCCAGCTGCCCGACAACCTGGAAAAGGGCACCGTGATCGAATCGA
TCGTCGAGGTCAAGGGCATGCTCAACCGGATCAAATGGACGATCGTGCACTACAAGCCGCCGGAAGCCATGACGCTCAAC
GGTGTCGGCGTCGGCGGGGTCAAGGTCAAACTGATCGCGAAGGTCAAGCCGAACGACGCCGGATCGATCGTCAGCTTCGA
CGTTCACCTCGGTGGCCCAGCGTTGTTCGGCCCGATCGGCATGATCGTTGCGGCGGCATTGCGAAGTGACATCGACGAGT
CCCTGGAAAGATTCGTCACGGTGTTCACCGCTCCCGATCCCGGTCGCAACGGACATGGGATTACCGGTCGCTGA

Antitoxin


Download         Length: 63 a.a.        Molecular weight: 6667.34 Da        Isoelectric Point: 4.9849

>AT36261 WP_163792496.1 NZ_AP022587:4931571-4931759 [Mycobacterium stomatepiae]
MGFLDKAKDLLAQNADKVETAIDKAGEFVDDKTQGKYSDTIHKVQEEAKKAAGSQAQGNQQG

Download         Length: 189 bp

>AT36261 NZ_AP022587:4931571-4931759 [Mycobacterium stomatepiae]
ATGGGATTCCTGGACAAGGCAAAGGACCTGTTGGCGCAGAACGCCGACAAGGTCGAGACCGCGATTGACAAGGCCGGCGA
GTTCGTCGACGACAAGACGCAGGGGAAGTACTCCGACACCATCCACAAGGTGCAGGAAGAGGCCAAGAAGGCCGCTGGCT
CTCAGGCTCAGGGCAACCAGCAGGGCTAG

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
No matching records found

References