Detailed information of TA system TA036260

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): pezAT/zeta-ParD
• Location: 2850043..2851046
• Replicon: chromosome
• Accession: NZ_AP022587
• Organism: Mycobacterium stomatepiae strain JCM 17783

Toxin (Protein)

• Gene name: pezT
• Uniprot ID: -
• Locus tag: G6N54_RS13305
• Protein ID: WP_163790549.1
• Coordinates: 2850043..2850621 (-)
• Length: 193 a.a.

Antitoxin (Protein)

• Gene name: pezA
• Uniprot ID: -
• Locus tag: G6N54_RS13310
• Protein ID: WP_163790550.1
• Coordinates: 2850618..2851046 (-)
• Length: 143 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
G6N54_RS13285	2845814..2846737	-	924	WP_163790546.1	DUF4436 domain-containing protein	-
G6N54_RS13290	2846688..2848562	-	1875	WP_163790547.1	glutamine--fructose-6-phosphate transaminase (isomerizing)	-
G6N54_RS13295	2848844..2849191	+	348	WP_163794718.1	DUF2510 domain-containing protein	-
G6N54_RS13300	2849201..2850040	+	840	WP_163790548.1	dienelactone hydrolase family protein	-
G6N54_RS13305	2850043..2850621	-	579	WP_163790549.1	zeta toxin family protein	Toxin
G6N54_RS13310	2850618..2851046	-	429	WP_163790550.1	hypothetical protein	Antitoxin
G6N54_RS13315	2851166..2852209	+	1044	WP_163790551.1	LLM class F420-dependent oxidoreductase	-
G6N54_RS13320	2852214..2853587	-	1374	WP_163790552.1	hypothetical protein	-
G6N54_RS13325	2853590..2853907	-	318	WP_163790553.1	hypothetical protein	-
G6N54_RS13330	2853950..2855287	-	1338	WP_163790554.1	phosphoglucosamine mutase	-
G6N54_RS13335	2855434..2855949	-	516	WP_163790555.1	30S ribosomal protein S9	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Zeta toxin domain (5-136)

Antitoxin

• ParD-like antitoxin of type II bacterial toxin-antitoxin system (7-106)

Sequences

Toxin

Protein

• Length: 193 a.a.
• Molecular weight: 21209.24 Da
• Isoelectric Point: 7.5231

>T36260 WP_163790549.1 NZ_AP022587:c2850621-2850043 [Mycobacterium stomatepiae]
MNRLDLVVGPNGAGKSTFVELTLAPLLPTSAFVNADEIARQRWPDDPAAHSYEAAQVAADTRARLIELRRSFIAETVFSH
PSKLELIDTAHTGAYTVVLHALLIPEELAVERVKRRVMAGGHEVPEDKIRERYQRLWPLVAIAITRSDTATVYDNSALKG
PRIVAQMSAGRLVGAPTWPTWAPSELTSRWHA

Nucleotide

• Length: 579 bp

>T36260 NZ_AP022587:c2850621-2850043 [Mycobacterium stomatepiae]
ATGAACCGGCTCGACCTGGTCGTCGGCCCCAACGGGGCGGGCAAATCGACCTTCGTCGAGCTCACGCTTGCGCCGCTGCT
GCCGACAAGCGCCTTCGTCAACGCGGACGAGATCGCCCGACAACGGTGGCCAGACGATCCCGCCGCACATTCCTACGAGG
CGGCCCAGGTCGCGGCCGACACCCGGGCGAGGCTCATCGAACTGCGCCGATCTTTCATCGCCGAAACAGTGTTTTCTCAC
CCGTCCAAACTCGAACTGATCGACACCGCCCACACGGGGGCCTACACCGTCGTCCTGCACGCCCTGCTCATCCCCGAGGA
GCTTGCCGTCGAACGCGTGAAACGCAGGGTCATGGCCGGCGGGCACGAAGTACCCGAGGACAAGATTCGTGAGCGGTATC
AACGTCTTTGGCCCTTGGTCGCCATCGCGATCACACGCAGTGACACCGCGACCGTCTATGACAACAGTGCGCTCAAAGGT
CCGCGCATCGTCGCTCAAATGAGCGCGGGCCGGCTCGTTGGTGCCCCTACTTGGCCGACGTGGGCGCCAAGCGAATTGAC
GTCGCGCTGGCACGCCTAG

Antitoxin

Protein

• Length: 143 a.a.
• Molecular weight: 15009.79 Da
• Isoelectric Point: 10.2543

>AT36260 WP_163790550.1 NZ_AP022587:c2851046-2850618 [Mycobacterium stomatepiae]
MADSAGRVTRFAADLVDSAAAEGARQSRSAKQQLDHWARVGRAVSSQHSAARRRVEAALAGDLELGELGVEEGVVFNAEI
AAAIQENLNESNYGALLAKRGVTTVALNEAGEIVEHRPDGTSTVLAAKPRPKRRKKVNAGAR

Nucleotide

• Length: 429 bp

>AT36260 NZ_AP022587:c2851046-2850618 [Mycobacterium stomatepiae]
ATGGCTGACAGTGCTGGTCGAGTGACCCGGTTCGCCGCGGACCTGGTCGATAGCGCCGCGGCCGAGGGGGCGCGGCAGAG
CCGTTCGGCCAAGCAGCAACTCGACCACTGGGCCCGGGTCGGGCGGGCGGTATCGAGCCAGCACTCGGCGGCCCGTCGCC
GCGTGGAGGCGGCGCTGGCGGGGGACCTGGAACTGGGCGAGCTGGGTGTCGAAGAGGGTGTCGTCTTCAACGCCGAGATC
GCCGCGGCGATCCAGGAAAACCTCAATGAGTCCAACTACGGTGCGCTGTTGGCCAAGCGCGGTGTCACCACGGTTGCCCT
CAACGAGGCCGGTGAGATCGTCGAGCACCGGCCCGACGGCACATCGACGGTGCTGGCCGCCAAGCCGCGACCCAAACGAC
GCAAGAAGGTGAACGCCGGGGCCCGATGA