Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/Txe-YefM
Location 2433572..2434110 Replicon chromosome
Accession NZ_AP022587
Organism Mycobacterium stomatepiae strain JCM 17783

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag G6N54_RS11555 Protein ID WP_163790281.1
Coordinates 2433853..2434110 (+) Length 86 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag G6N54_RS11550 Protein ID WP_163790280.1
Coordinates 2433572..2433856 (+) Length 95 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
G6N54_RS11535 2429241..2431292 - 2052 WP_163790277.1 NADH:flavin oxidoreductase -
G6N54_RS11540 2431468..2432859 + 1392 WP_163790278.1 L-serine ammonia-lyase -
G6N54_RS11545 2432952..2433239 + 288 WP_163790279.1 transposase family protein -
G6N54_RS11550 2433572..2433856 + 285 WP_163790280.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
G6N54_RS11555 2433853..2434110 + 258 WP_163790281.1 Txe/YoeB family addiction module toxin Toxin
G6N54_RS11560 2435415..2436653 - 1239 WP_197939595.1 FAD-dependent monooxygenase -
G6N54_RS11565 2437126..2437371 - 246 WP_163790283.1 transposase -
G6N54_RS11570 2437254..2437589 - 336 WP_163787993.1 hypothetical protein -
G6N54_RS11575 2437742..2438113 + 372 WP_163794675.1 cupin domain-containing protein -
G6N54_RS11580 2438163..2438791 - 629 Protein_2312 ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(4-85)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(2-70)


Sequences

Toxin        


Download         Length: 86 a.a.        Molecular weight: 10113.49 Da        Isoelectric Point: 9.7850

>T36259 WP_163790281.1 NZ_AP022587:2433853-2434110 [Mycobacterium stomatepiae]
VRSINFDPDAWEDFLYWLASDRRVARRITRLIGEIQRDPFAGIGKPEPLKGELSGYLSRRIDDEHRLVYRTGHNEVKILK
ARYHY

Download         Length: 258 bp

>T36259 NZ_AP022587:2433853-2434110 [Mycobacterium stomatepiae]
GTGAGAAGCATCAACTTCGATCCTGACGCCTGGGAGGACTTCTTGTACTGGTTGGCCTCCGACCGCAGGGTGGCCCGTCG
GATCACCCGACTCATCGGAGAGATCCAACGCGACCCGTTCGCAGGAATCGGGAAACCGGAGCCGCTCAAGGGGGAGCTGT
CGGGCTACTTGTCGCGGCGGATCGACGACGAACACCGTCTCGTGTACCGAACAGGCCACAACGAAGTCAAGATCCTGAAA
GCCCGCTACCACTACTGA

Antitoxin


Download         Length: 95 a.a.        Molecular weight: 10524.82 Da        Isoelectric Point: 4.5332

>AT36259 WP_163790280.1 NZ_AP022587:2433572-2433856 [Mycobacterium stomatepiae]
MAISASEARQRLFPLLEQVNNDHEPVRITSKAGEAVLMSAADYDSWQETVYLLRSPENARRLMEAVARDKTSLLAPANYT
KSIDELEEMAGGRE

Download         Length: 285 bp

>AT36259 NZ_AP022587:2433572-2433856 [Mycobacterium stomatepiae]
ATGGCCATCAGTGCAAGTGAAGCTCGACAGCGCCTCTTCCCGCTCCTCGAACAGGTCAACAACGACCATGAACCTGTGCG
CATCACCTCCAAGGCCGGCGAGGCGGTGCTCATGTCAGCCGCCGACTATGACTCGTGGCAAGAAACGGTCTATCTACTCC
GTTCGCCCGAGAACGCACGCCGACTTATGGAGGCCGTGGCCCGAGACAAGACCAGCCTCCTTGCCCCAGCCAACTACACG
AAGTCGATCGACGAACTTGAGGAGATGGCCGGCGGCCGGGAGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References