Detailed information of TA system TA036216

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): pezAT/zeta-ParD
• Location: 4424042..4425047
• Replicon: chromosome
• Accession: NZ_AP022579
• Organism: Mycolicibacterium boenickei strain JCM 15653

Toxin (Protein)

• Gene name: pezT
• Uniprot ID: -
• Locus tag: G6N57_RS21030
• Protein ID: WP_077740740.1
• Coordinates: 4424042..4424620 (-)
• Length: 193 a.a.

Antitoxin (Protein)

• Gene name: pezA
• Uniprot ID: -
• Locus tag: G6N57_RS21035
• Protein ID: WP_077740739.1
• Coordinates: 4424658..4425047 (-)
• Length: 130 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
-	4424658..4425047	-	390	-	-	Antitoxin

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Zeta toxin domain (4-135)

Antitoxin

• ParD-like antitoxin of type II bacterial toxin-antitoxin system (6-106)

Sequences

Toxin

Protein

• Length: 193 a.a.
• Molecular weight: 20860.95 Da
• Isoelectric Point: 7.0296

>T36216 WP_077740740.1 NZ_AP022579:c4424620-4424042 [Mycolicibacterium boenickei]
VKRLDLVVGCNGAGKSTFVELTLSPLLPGCPFVNADEIAKRRWPENPAPHSYEAALVAAETRAKLIELGESFIAETVFSH
PSKLELIDDACAAGYTVILHCILIPEDLAVQRVRHRVQAGGHDVPEAKIRERYQRLWGLVAIAAMHADSATFYDNSTVNG
PRIVAQLAGGFVVGSPTWPKWTPAVLSSRWPG

Nucleotide

• Length: 579 bp

>T36216 NZ_AP022579:c4424620-4424042 [Mycolicibacterium boenickei]
GTGAAACGCCTCGACCTCGTCGTCGGCTGCAACGGCGCCGGCAAGTCCACCTTCGTCGAACTCACCCTGTCACCGCTGCT
CCCCGGCTGCCCGTTCGTGAACGCGGACGAGATCGCCAAGCGACGCTGGCCCGAGAACCCTGCCCCGCACTCCTACGAGG
CGGCCCTGGTCGCCGCCGAAACGCGGGCCAAACTCATCGAGCTCGGTGAGTCCTTCATCGCCGAGACGGTGTTCTCCCAT
CCCTCCAAGCTCGAGCTGATCGACGACGCATGCGCCGCCGGGTACACCGTGATCCTGCACTGCATTCTGATCCCCGAAGA
CCTGGCCGTGCAGCGAGTGCGTCACCGCGTGCAGGCCGGTGGACATGACGTCCCCGAAGCCAAGATCCGCGAACGCTACC
AACGACTTTGGGGTCTCGTCGCGATCGCCGCGATGCACGCGGACTCGGCGACGTTCTACGACAACAGCACTGTCAACGGC
CCGCGCATCGTCGCTCAACTGGCCGGCGGATTCGTCGTCGGATCACCCACGTGGCCGAAATGGACACCCGCGGTGCTGAG
TTCGCGCTGGCCCGGTTAG

Antitoxin

Protein

• Length: 130 a.a.
• Molecular weight: 13778.24 Da
• Isoelectric Point: 5.2233

>AT36216 WP_077740739.1 NZ_AP022579:c4425047-4424658 [Mycolicibacterium boenickei]
MTETADRVTRFAADLMDSAAAEGARQSRSAKQQLDHWARVGRAVSSQHSAARRKVESALAGSTPLRELTAEEGAVFDAEI
AASIEENLARADYGKILAGRGITTVALDENGEIVQYRPDGTTTVLAHPQ

Nucleotide

• Length: 390 bp

>AT36216 NZ_AP022579:c4425047-4424658 [Mycolicibacterium boenickei]
ATGACCGAGACCGCAGACCGGGTGACCCGGTTCGCCGCTGATCTCATGGACAGTGCCGCCGCGGAAGGCGCACGTCAGAG
CCGGTCGGCCAAGCAGCAACTCGACCACTGGGCCCGCGTGGGACGGGCGGTGTCCAGCCAGCACAGCGCGGCACGCCGCA
AGGTGGAGTCCGCTCTGGCGGGCAGTACTCCCCTGCGGGAGTTGACCGCCGAGGAAGGTGCCGTGTTCGACGCCGAGATC
GCCGCTTCCATAGAAGAGAACCTGGCGCGTGCCGACTACGGCAAGATCCTGGCCGGACGCGGCATCACCACCGTGGCGCT
CGACGAGAACGGCGAGATCGTGCAGTACCGCCCCGACGGCACCACCACGGTACTGGCGCACCCGCAGTGA