Detailed information of TA system TA036215

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): unclassified/Polyketide_cyc2(toxin)
• Location: 2413468..2414100
• Replicon: chromosome
• Accession: NZ_AP022579
• Organism: Mycolicibacterium boenickei strain JCM 15653

Toxin (Protein)

• Gene name: novel[antitoxin]
• Uniprot ID: -
• Locus tag: G6N57_RS11445
• Protein ID: WP_077740512.1
• Coordinates: 2413651..2414100 (+)
• Length: 150 a.a.

Antitoxin (Protein)

• Gene name: novel[toxin]
• Uniprot ID: A0A7I7N5G7
• Locus tag: G6N57_RS11440
• Protein ID: WP_036447720.1
• Coordinates: 2413468..2413647 (+)
• Length: 60 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Polyketide cyclase/dehydrase (1-145)

Antitoxin

• Antitoxin Rv0909/MT0933 (4-52)

Sequences

Toxin

Protein

• Length: 150 a.a.
• Molecular weight: 16086.66 Da
• Isoelectric Point: 9.8774

>T36215 WP_077740512.1 NZ_AP022579:2413651-2414100 [Mycolicibacterium boenickei]
MAKLSVSVDVPLPPEKAWEYASDLSRYDEWLSIHRAWRSKLPETLEKGTVIDSIVEVKGMLNRVKWTLVNYKPPQSLTLN
GDGRGGVKVKLIGKIAPAQVDGGEGAKVSFDVHLGGPALFGPIGMVVAAALKGDIQQSLNKFKALYASS

Nucleotide

• Length: 450 bp

>T36215 NZ_AP022579:2413651-2414100 [Mycolicibacterium boenickei]
ATGGCTAAATTGTCTGTCTCCGTCGATGTTCCATTGCCGCCGGAGAAGGCGTGGGAGTACGCCTCTGATCTGTCCCGGTA
CGACGAGTGGCTCAGCATCCACCGCGCCTGGCGGTCGAAGTTGCCCGAGACCCTGGAAAAGGGCACGGTCATCGACTCGA
TCGTCGAAGTCAAGGGCATGCTGAACCGTGTGAAGTGGACGCTGGTGAATTACAAGCCACCGCAGTCCCTGACCCTCAAC
GGCGATGGCCGTGGCGGGGTAAAGGTCAAGCTGATCGGAAAGATCGCTCCGGCCCAGGTTGACGGCGGCGAGGGCGCGAA
AGTGTCCTTCGACGTGCATCTAGGAGGGCCTGCCCTGTTCGGGCCGATCGGCATGGTGGTCGCGGCCGCGCTCAAGGGCG
ATATCCAGCAGTCGCTGAACAAGTTCAAGGCGCTCTACGCGTCGTCGTAG

Antitoxin

Protein

• Length: 60 a.a.
• Molecular weight: 6392.07 Da
• Isoelectric Point: 4.4883

>AT36215 WP_036447720.1 NZ_AP022579:2413468-2413647 [Mycolicibacterium boenickei]
MGFLDKAKDLLSQNADKVEQAIDKAGDIVDEKTQGKYSGAVDKAQEAAKNAINKEEPQQ

Nucleotide

• Length: 180 bp

>AT36215 NZ_AP022579:2413468-2413647 [Mycolicibacterium boenickei]
ATGGGATTCCTGGACAAGGCCAAGGACCTTCTGTCTCAGAACGCGGACAAGGTAGAGCAGGCCATCGACAAGGCCGGCGA
CATCGTCGACGAGAAGACGCAGGGCAAGTACTCCGGCGCGGTCGACAAGGCACAGGAAGCGGCGAAGAACGCCATCAACA
AGGAAGAACCGCAGCAGTAA

Structures

Antitoxin

• AlphaFold DB: A0A7I7N5G7