36184

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) unclassified/Polyketide_cyc2(toxin)
Location 98677..99295 Replicon chromosome
Accession NZ_AP022575
Organism Mycobacterium shinjukuense strain JCM 14233

Toxin (Protein)


Gene name novel[antitoxin] Uniprot ID -
Locus tag G6N20_RS00380 Protein ID WP_083050223.1
Coordinates 98849..99295 (+) Length 149 a.a.

Antitoxin (Protein)


Gene name novel[toxin] Uniprot ID -
Locus tag G6N20_RS00375 Protein ID WP_142272123.1
Coordinates 98677..98844 (+) Length 56 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
G6N20_RS00365 94573..96156 + 1584 WP_083050218.1 serine hydrolase -
G6N20_RS00370 96153..98534 + 2382 WP_083050221.1 cation-translocating P-type ATPase -
G6N20_RS00375 98677..98844 + 168 WP_142272123.1 antitoxin Antitoxin
G6N20_RS00380 98849..99295 + 447 WP_083050223.1 SRPBCC family protein Toxin
G6N20_RS00385 99365..100138 + 774 WP_083050250.1 VOC family protein -
G6N20_RS00390 100243..100677 + 435 WP_083050225.1 hypothetical protein -
G6N20_RS00395 100683..101165 - 483 WP_083050253.1 VOC family protein -
G6N20_RS00400 101168..102676 - 1509 WP_083050228.1 carotenoid oxygenase family protein -
G6N20_RS00405 102678..103904 - 1227 WP_083050231.1 acetyl-CoA acetyltransferase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Polyketide cyclase/dehydrase

(1-142)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 149 a.a.        Molecular weight: 16352.05 Da        Isoelectric Point: 10.4569

>T36184 WP_083050223.1 NZ_AP022575:98849-99295 [Mycobacterium shinjukuense]
MAKLSGSIDVPLPPEQAWTHASDLTRYREWLTIHKVWRSKLPDVLEKGTVVESYVEVKGMPNRIRWTIVRYRPPEGMTLD
GDGVGGVKVKLIAKVAPKGDGSVVSFDVHLGGPALFGPLGMIVAAALRTDIRESLQNFVRVFAPARHR

Download         Length: 447 bp

>T36184 NZ_AP022575:98849-99295 [Mycobacterium shinjukuense]
ATGGCGAAGCTGTCCGGATCCATCGACGTACCGCTGCCGCCGGAGCAAGCCTGGACGCATGCCTCCGATCTGACCCGCTA
CCGGGAATGGCTGACGATCCACAAGGTGTGGCGCAGCAAGTTGCCCGACGTCTTGGAAAAGGGCACGGTCGTCGAATCGT
ACGTCGAGGTCAAGGGCATGCCCAACCGGATCAGGTGGACCATCGTGCGGTACCGGCCGCCGGAAGGCATGACGCTCGAC
GGCGACGGCGTCGGCGGTGTCAAGGTCAAGCTAATCGCCAAGGTCGCACCAAAAGGTGACGGCTCGGTCGTCAGCTTCGA
CGTACACCTGGGCGGGCCAGCGCTGTTCGGGCCCCTCGGCATGATCGTCGCCGCCGCACTGCGGACTGACATCCGCGAAT
CGCTGCAGAATTTCGTCAGGGTGTTCGCGCCGGCCCGGCACCGATGA

Antitoxin


Download         Length: 56 a.a.        Molecular weight: 5689.45 Da        Isoelectric Point: 4.8288

>AT36184 WP_142272123.1 NZ_AP022575:98677-98844 [Mycobacterium shinjukuense]
MGILDKARDPRSRIVDKVETVITLAGGCVDAQGSCCGSTVPEQATKVVAAGDQRD

Download         Length: 168 bp

>AT36184 NZ_AP022575:98677-98844 [Mycobacterium shinjukuense]
ATGGGAATTCTGGACAAGGCAAGAGACCCGCGGTCACGCATCGTCGACAAGGTCGAGACGGTGATCACCCTGGCGGGTGG
GTGCGTCGACGCCCAGGGCAGCTGTTGCGGCAGCACCGTGCCGGAGCAGGCCACGAAGGTCGTCGCCGCCGGCGACCAGC
GGGACTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References