Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/ParE-RHH
Location 1339813..1340354 Replicon chromosome
Accession NZ_AP022570
Organism Mycolicibacterium poriferae strain JCM 12603

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag G6N39_RS06440 Protein ID WP_163672990.1
Coordinates 1340061..1340354 (+) Length 98 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID -
Locus tag G6N39_RS06435 Protein ID WP_163672989.1
Coordinates 1339813..1340064 (+) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
G6N39_RS06400 1335030..1335557 + 528 WP_163672984.1 hypothetical protein -
G6N39_RS06405 1335631..1336656 - 1026 WP_163672985.1 NAD(P)H-dependent glycerol-3-phosphate dehydrogenase -
G6N39_RS06410 1336781..1337038 + 258 WP_163672986.1 ribbon-helix-helix domain-containing protein -
G6N39_RS06415 1337025..1337456 + 432 WP_163672987.1 type II toxin-antitoxin system VapC family toxin -
G6N39_RS06420 1337463..1337954 - 492 WP_152515473.1 YajQ family cyclic di-GMP-binding protein -
G6N39_RS06430 1338293..1339720 - 1428 WP_163672988.1 serine hydrolase -
G6N39_RS06435 1339813..1340064 + 252 WP_163672989.1 type II toxin-antitoxin system ParD family antitoxin Antitoxin
G6N39_RS06440 1340061..1340354 + 294 WP_163672990.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
G6N39_RS06445 1340362..1341405 - 1044 WP_163672991.1 PQQ-dependent sugar dehydrogenase -
G6N39_RS06450 1341404..1342399 + 996 WP_163679869.1 endonuclease/exonuclease/phosphatase family protein -
G6N39_RS06455 1342549..1345308 + 2760 WP_163672992.1 LuxR family transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-91)

Antitoxin

Antitoxin ParD

(4-72)


Sequences

Toxin        


Download         Length: 98 a.a.        Molecular weight: 11436.02 Da        Isoelectric Point: 6.8704

>T36170 WP_163672990.1 NZ_AP022570:1340061-1340354 [Mycolicibacterium poriferae]
VNRYLLSPAAQADLEQIWAFSVDRWGRDQAENYLREIQRGIDRVADNPMIGRVCDEVRSGYRRHPVGSHVLFYRVEGNMI
DVVRILHKRMEMDLHLD

Download         Length: 294 bp

>T36170 NZ_AP022570:1340061-1340354 [Mycolicibacterium poriferae]
GTGAACCGTTATCTCCTTTCTCCCGCCGCTCAGGCTGACCTGGAACAAATCTGGGCTTTCAGCGTCGACCGCTGGGGCCG
CGATCAAGCCGAGAATTACCTACGGGAAATCCAGCGGGGCATAGACCGGGTCGCGGACAACCCGATGATCGGACGTGTCT
GTGATGAGGTGCGGAGCGGCTATCGGCGTCATCCGGTCGGATCGCACGTGCTGTTCTACCGCGTCGAGGGCAACATGATC
GATGTCGTGCGAATTCTGCACAAGCGCATGGAGATGGACCTCCACCTCGACTGA

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9447.52 Da        Isoelectric Point: 5.8769

>AT36170 WP_163672989.1 NZ_AP022570:1339813-1340064 [Mycolicibacterium poriferae]
VGKNTSFSLDEHFSAFIEGEVASGRYRSASDVVRTALRLLEERELRLRALRQALIDGERSGESTPFDFDDFIARKRAEAP
PYR

Download         Length: 252 bp

>AT36170 NZ_AP022570:1339813-1340064 [Mycolicibacterium poriferae]
GTGGGTAAGAACACCTCGTTCAGTCTCGACGAGCACTTCAGCGCATTCATCGAGGGAGAAGTGGCCTCCGGCCGCTACCG
CTCAGCAAGCGATGTCGTGCGCACTGCTTTGCGGCTGCTCGAGGAACGCGAGCTGAGGCTCCGGGCTCTGCGGCAGGCGC
TCATCGACGGTGAACGCAGTGGGGAATCCACACCGTTCGACTTCGACGACTTCATCGCACGCAAGCGTGCCGAGGCCCCG
CCTTACCGGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References