36153

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) phd-doc/Fic(toxin)
Location 2690424..2691001 Replicon chromosome
Accession NZ_AP022564
Organism Mycolicibacter terrae strain JCM 12143

Toxin (Protein)


Gene name doc Uniprot ID -
Locus tag G6N23_RS12915 Protein ID WP_085259683.1
Coordinates 2690618..2691001 (+) Length 128 a.a.

Antitoxin (Protein)


Gene name phd Uniprot ID -
Locus tag G6N23_RS12910 Protein ID WP_085259684.1
Coordinates 2690424..2690621 (+) Length 66 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
G6N23_RS12885 2685690..2686364 - 675 WP_165758668.1 DUF5642 family protein -
G6N23_RS12890 2686414..2687310 - 897 WP_085259688.1 GTPase Era -
G6N23_RS12895 2687410..2688708 - 1299 WP_085259687.1 hemolysin family protein -
G6N23_RS12900 2688705..2689241 - 537 WP_085259686.1 rRNA maturation RNase YbeY -
G6N23_RS12905 2689238..2690290 - 1053 WP_085259685.1 PhoH family protein -
G6N23_RS12910 2690424..2690621 + 198 WP_085259684.1 antitoxin Phd Antitoxin
G6N23_RS12915 2690618..2691001 + 384 WP_085259683.1 Fic family protein Toxin
G6N23_RS12920 2691049..2691696 + 648 WP_085259701.1 methyltransferase domain-containing protein -
G6N23_RS12925 2691675..2692376 - 702 WP_085259682.1 AraC family transcriptional regulator -
G6N23_RS12930 2692382..2693125 - 744 WP_085259681.1 16S rRNA (uracil(1498)-N(3))-methyltransferase -
G6N23_RS12935 2693129..2694280 - 1152 WP_085259680.1 molecular chaperone DnaJ -
G6N23_RS12940 2694314..2695357 - 1044 WP_085259679.1 heat-inducible transcriptional repressor HrcA -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Fido domain

(28-83)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 128 a.a.        Molecular weight: 13589.27 Da        Isoelectric Point: 3.8561

>T36153 WP_085259683.1 NZ_AP022564:2690618-2691001 [Mycolicibacter terrae]
MTEFLDRDDLLVAGAFAVSHACEVGDYGLLDAAVARPQATVFGVDAYPDLYAKAAALLQSLARNHALVDGNMRTAWASAW
TFLYLNACELSPDFDVDAAEVFMNDVAQRGELPVEDIAATLASFAVT

Download         Length: 384 bp

>T36153 NZ_AP022564:2690618-2691001 [Mycolicibacter terrae]
TTGACCGAATTTCTCGACCGCGATGACCTGCTCGTCGCCGGGGCGTTCGCCGTGAGCCACGCCTGCGAAGTCGGGGACTA
CGGGTTGCTCGACGCCGCAGTCGCCCGGCCTCAAGCCACGGTCTTCGGTGTGGACGCCTATCCCGATCTGTACGCGAAGG
CGGCGGCGTTGCTGCAATCACTGGCCCGCAACCATGCCCTGGTGGACGGCAACATGCGCACCGCCTGGGCGTCGGCATGG
ACGTTTCTGTACCTCAACGCCTGTGAGCTCTCCCCGGACTTCGACGTCGATGCGGCCGAGGTGTTCATGAACGACGTGGC
ACAGCGCGGAGAGCTGCCGGTCGAGGACATCGCCGCCACGCTGGCATCATTCGCCGTTACGTGA

Antitoxin


Download         Length: 66 a.a.        Molecular weight: 7022.95 Da        Isoelectric Point: 11.5969

>AT36153 WP_085259684.1 NZ_AP022564:2690424-2690621 [Mycolicibacter terrae]
VPSLNITFTEEELAAVRAAAGEQNLSLRVFAHRAVVTAASDHRRRVAEAAALVAQRSAELNRRLA

Download         Length: 198 bp

>AT36153 NZ_AP022564:2690424-2690621 [Mycolicibacter terrae]
GTGCCGTCGCTGAACATCACCTTCACCGAGGAGGAACTGGCCGCCGTCCGCGCCGCGGCCGGGGAACAGAACCTCTCGCT
GCGGGTATTCGCGCACCGGGCGGTCGTCACCGCCGCCAGCGACCACCGGCGCCGCGTCGCCGAAGCGGCAGCGCTGGTCG
CACAACGCTCCGCCGAGTTGAATCGCCGCCTGGCTTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References