36105

Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2193553..2193821 Replicon chromosome
Accession NZ_AP022549
Organism Escherichia coli strain THO-015

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2193681..2193783 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2193553..2193821 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JLF69_RS10455 2190106..2190768 - 663 WP_000944256.1 exodeoxyribonuclease X -
JLF69_RS10460 2190792..2191448 - 657 WP_000011664.1 carbon-nitrogen hydrolase family protein -
JLF69_RS10465 2191550..2191780 - 231 WP_000916763.1 DNA polymerase III subunit theta -
JLF69_RS10470 2191919..2192293 + 375 WP_000168747.1 CopC domain-containing protein YobA -
JLF69_RS10475 2192297..2193169 + 873 WP_000879317.1 copper homeostasis membrane protein CopD -
JLF69_RS10480 2193182..2193523 + 342 WP_000976472.1 YebY family protein -
- 2193553..2193821 - 269 - - Antitoxin
- 2193681..2193783 + 103 - - Toxin
JLF69_RS10485 2193918..2194574 + 657 WP_000812745.1 protein-serine/threonine phosphatase -
JLF69_RS10490 2194575..2194766 - 192 WP_001296140.1 YebW family protein -
JLF69_RS10495 2194871..2195107 - 237 WP_001295499.1 DUF1480 family protein -
JLF69_RS10500 2195224..2196663 - 1440 WP_001296139.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 2168383..2209660 41277


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T36105 NZ_AP022549:2193681-2193783 [Escherichia coli]
GCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 269 bp

>AT36105 NZ_AP022549:c2193821-2193553 [Escherichia coli]
AAAGTCAGCGAAGGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCTCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTTAAATATTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References