Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2117891..2118162 Replicon chromosome
Accession NZ_AP022540
Organism Escherichia coli strain THO-010

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2118021..2118124 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2117891..2118162 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JLH08_RS09945 2114446..2115108 - 663 WP_000944256.1 exodeoxyribonuclease X -
JLH08_RS09950 2115132..2115788 - 657 WP_000011660.1 carbon-nitrogen hydrolase family protein -
JLH08_RS09955 2115890..2116120 - 231 WP_000916763.1 DNA polymerase III subunit theta -
JLH08_RS09960 2116259..2116633 + 375 WP_021556896.1 CopC domain-containing protein YobA -
JLH08_RS09965 2116637..2117509 + 873 WP_000879298.1 copper homeostasis membrane protein CopD -
JLH08_RS09970 2117522..2117863 + 342 WP_000976472.1 YebY family protein -
- 2117891..2118162 - 272 - - Antitoxin
- 2118021..2118124 + 104 - - Toxin
JLH08_RS09975 2118259..2118915 + 657 WP_021556895.1 protein-serine/threonine phosphatase -
JLH08_RS09980 2118916..2119107 - 192 WP_001313035.1 YebW family protein -
JLH08_RS09985 2119212..2119448 - 237 WP_001295499.1 DUF1480 family protein -
JLH08_RS09990 2119566..2121005 - 1440 WP_024227172.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T36046 NZ_AP022540:2118021-2118124 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT36046 NZ_AP022540:c2118162-2117891 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References