Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2153998..2154269 Replicon chromosome
Accession NZ_AP022536
Organism Escherichia coli strain THO-008

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2154128..2154231 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2153998..2154269 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JLF34_RS09985 2150553..2151215 - 663 WP_000944256.1 exodeoxyribonuclease X -
JLF34_RS09990 2151239..2151895 - 657 WP_000011653.1 carbon-nitrogen hydrolase family protein -
JLF34_RS09995 2151997..2152227 - 231 WP_000916763.1 DNA polymerase III subunit theta -
JLF34_RS10000 2152366..2152740 + 375 WP_000168743.1 CopC domain-containing protein YobA -
JLF34_RS10005 2152744..2153616 + 873 WP_001587145.1 copper homeostasis membrane protein CopD -
JLF34_RS10010 2153629..2153970 + 342 WP_000976481.1 YebY family protein -
- 2153998..2154269 - 272 - - Antitoxin
- 2154128..2154231 + 104 - - Toxin
JLF34_RS10015 2154366..2155022 + 657 WP_000812712.1 protein-serine/threonine phosphatase -
JLF34_RS10020 2155023..2155214 - 192 WP_001296140.1 YebW family protein -
JLF34_RS10025 2155319..2155555 - 237 WP_001295499.1 DUF1480 family protein -
JLF34_RS10030 2155673..2157112 - 1440 WP_001309555.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 2146688..2170109 23421


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T36015 NZ_AP022536:2154128-2154231 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT36015 NZ_AP022536:c2154269-2153998 [Escherichia coli]
AAAGTCAGCGAAGGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References