Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1808324..1808469 Replicon chromosome
Accession NZ_AP022527
Organism Klebsiella pneumoniae strain THO-004

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1808360..1808462 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1808324..1808469 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JLF70_RS08755 1803454..1805514 + 2061 WP_004151449.1 oligopeptidase B -
JLF70_RS08760 1805518..1806177 - 660 WP_002911407.1 exodeoxyribonuclease X -
JLF70_RS08765 1806256..1806486 - 231 WP_002911406.1 DNA polymerase III subunit theta -
JLF70_RS08770 1806599..1806973 + 375 WP_004151448.1 CopC domain-containing protein YobA -
JLF70_RS08775 1806977..1807846 + 870 WP_009307538.1 copper homeostasis membrane protein CopD -
JLF70_RS08780 1807863..1808201 + 339 WP_009307539.1 YebY family protein -
- 1808324..1808469 - 146 - - Antitoxin
- 1808360..1808462 + 103 - - Toxin
JLF70_RS08785 1808838..1808981 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
JLF70_RS08790 1809086..1810054 - 969 WP_004151446.1 VirK/YbjX family protein -
JLF70_RS08795 1810211..1810864 + 654 WP_009307541.1 protein-serine/threonine phosphatase -
JLF70_RS08800 1810861..1811052 - 192 WP_002911395.1 YebW family protein -
JLF70_RS08805 1811150..1811389 - 240 WP_002911393.1 YebV family protein -
JLF70_RS08810 1811505..1812938 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T35947 NZ_AP022527:1808360-1808462 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT35947 NZ_AP022527:c1808469-1808324 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References