Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2295531..2295799 Replicon chromosome
Accession NZ_AP022525
Organism Escherichia coli strain THO-003

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2295659..2295761 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2295531..2295799 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JLF28_RS11110 2292084..2292746 - 663 WP_000944256.1 exodeoxyribonuclease X -
JLF28_RS11115 2292770..2293426 - 657 WP_000011664.1 carbon-nitrogen hydrolase family protein -
JLF28_RS11120 2293528..2293758 - 231 WP_000916763.1 DNA polymerase III subunit theta -
JLF28_RS11125 2293897..2294271 + 375 WP_000168747.1 CopC domain-containing protein YobA -
JLF28_RS11130 2294275..2295147 + 873 WP_000879317.1 copper homeostasis membrane protein CopD -
JLF28_RS11135 2295160..2295501 + 342 WP_000976472.1 YebY family protein -
- 2295531..2295799 - 269 - - Antitoxin
- 2295659..2295761 + 103 - - Toxin
JLF28_RS11140 2295896..2296552 + 657 WP_000812745.1 protein-serine/threonine phosphatase -
JLF28_RS11145 2296553..2296744 - 192 WP_001296140.1 YebW family protein -
JLF28_RS11150 2296849..2297085 - 237 WP_001295499.1 DUF1480 family protein -
JLF28_RS11155 2297202..2298641 - 1440 WP_001296139.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 2214983..2311638 96655


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T35918 NZ_AP022525:2295659-2295761 [Escherichia coli]
GCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 269 bp

>AT35918 NZ_AP022525:c2295799-2295531 [Escherichia coli]
AAAGTCAGCGAAGGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCTCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTTAAATATTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References