Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | PumAB/COG3657-dnstrm_HI1420 |
Location | 4757833..4758421 | Replicon | chromosome |
Accession | NZ_AP022513 | ||
Organism | Citrobacter portucalensis strain STN0717-72 |
Toxin (Protein)
Gene name | PumA | Uniprot ID | - |
Locus tag | JLF48_RS22885 | Protein ID | WP_063941209.1 |
Coordinates | 4757833..4758150 (+) | Length | 106 a.a. |
Antitoxin (Protein)
Gene name | PumB | Uniprot ID | A0A5B0STC7 |
Locus tag | JLF48_RS22890 | Protein ID | WP_032942057.1 |
Coordinates | 4758143..4758421 (+) | Length | 93 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
JLF48_RS22860 | 4753601..4754425 | + | 825 | WP_200920925.1 | PTS system mannose/fructose/sorbose family transporter subunit IID | - |
JLF48_RS22865 | 4754494..4755717 | + | 1224 | WP_200920926.1 | zinc-binding dehydrogenase | - |
JLF48_RS22870 | 4755719..4756531 | + | 813 | WP_063941212.1 | shikimate 5-dehydrogenase | - |
JLF48_RS22875 | 4756581..4756886 | - | 306 | WP_032934126.1 | hypothetical protein | - |
JLF48_RS22880 | 4757018..4757569 | + | 552 | WP_200920927.1 | AAA family ATPase | - |
JLF48_RS22885 | 4757833..4758150 | + | 318 | WP_063941209.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
JLF48_RS22890 | 4758143..4758421 | + | 279 | WP_032942057.1 | putative addiction module antidote protein | Antitoxin |
JLF48_RS22895 | 4758532..4759221 | + | 690 | WP_200921622.1 | dipeptidase PepE | - |
JLF48_RS22900 | 4759336..4760967 | - | 1632 | WP_003826514.1 | Na/Pi cotransporter family protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 106 a.a. Molecular weight: 12110.09 Da Isoelectric Point: 10.1413
>T35884 WP_063941209.1 NZ_AP022513:4757833-4758150 [Citrobacter portucalensis]
IMEILQTMVFRRWEQNLRDRRAKTLIATRLFRLANGLSGDVKPVGEGVSEMRISYGPGYRIYFKQQGCRIIILLCGGDKS
SQANDITLAKMLARSLDYQEVFRHE
IMEILQTMVFRRWEQNLRDRRAKTLIATRLFRLANGLSGDVKPVGEGVSEMRISYGPGYRIYFKQQGCRIIILLCGGDKS
SQANDITLAKMLARSLDYQEVFRHE
Download Length: 318 bp
>T35884 NZ_AP022513:4757833-4758150 [Citrobacter portucalensis]
ATCATGGAAATTCTTCAGACAATGGTTTTCCGGCGTTGGGAGCAAAACCTACGGGACAGGAGAGCTAAAACGCTCATTGC
CACACGCCTTTTTCGTTTGGCTAATGGTTTATCTGGTGATGTAAAACCTGTTGGGGAAGGCGTCAGCGAAATGCGCATTT
CTTACGGTCCTGGCTACAGGATTTACTTTAAACAGCAAGGCTGCCGCATCATCATTTTGTTATGTGGGGGCGATAAAAGC
TCACAAGCCAACGATATTACTCTTGCAAAAATGCTTGCCCGTTCACTGGATTATCAGGAGGTCTTCCGCCATGAATAA
ATCATGGAAATTCTTCAGACAATGGTTTTCCGGCGTTGGGAGCAAAACCTACGGGACAGGAGAGCTAAAACGCTCATTGC
CACACGCCTTTTTCGTTTGGCTAATGGTTTATCTGGTGATGTAAAACCTGTTGGGGAAGGCGTCAGCGAAATGCGCATTT
CTTACGGTCCTGGCTACAGGATTTACTTTAAACAGCAAGGCTGCCGCATCATCATTTTGTTATGTGGGGGCGATAAAAGC
TCACAAGCCAACGATATTACTCTTGCAAAAATGCTTGCCCGTTCACTGGATTATCAGGAGGTCTTCCGCCATGAATAA
Antitoxin
Download Length: 93 a.a. Molecular weight: 9872.45 Da Isoelectric Point: 5.8233
>AT35884 WP_032942057.1 NZ_AP022513:4758143-4758421 [Citrobacter portucalensis]
MNKLTHYDPATALVDDEEIAVFMADALETGDAAYIAKALGVVARAKGMANIAAETGLSREQLYRSFSEKGNPTLKTTLAV
MKVLGIELTLKK
MNKLTHYDPATALVDDEEIAVFMADALETGDAAYIAKALGVVARAKGMANIAAETGLSREQLYRSFSEKGNPTLKTTLAV
MKVLGIELTLKK
Download Length: 279 bp
>AT35884 NZ_AP022513:4758143-4758421 [Citrobacter portucalensis]
ATGAATAAACTTACTCACTACGATCCCGCGACTGCGCTGGTTGATGATGAAGAAATTGCCGTGTTTATGGCCGATGCCCT
CGAAACAGGTGATGCAGCATACATTGCAAAAGCACTGGGCGTGGTGGCTCGTGCTAAGGGTATGGCGAACATCGCAGCAG
AAACGGGATTATCCCGCGAGCAGCTTTATCGCTCTTTTAGTGAGAAAGGTAACCCGACGCTGAAAACCACACTTGCGGTG
ATGAAGGTGCTCGGTATTGAATTGACACTTAAAAAATAG
ATGAATAAACTTACTCACTACGATCCCGCGACTGCGCTGGTTGATGATGAAGAAATTGCCGTGTTTATGGCCGATGCCCT
CGAAACAGGTGATGCAGCATACATTGCAAAAGCACTGGGCGTGGTGGCTCGTGCTAAGGGTATGGCGAACATCGCAGCAG
AAACGGGATTATCCCGCGAGCAGCTTTATCGCTCTTTTAGTGAGAAAGGTAACCCGACGCTGAAAACCACACTTGCGGTG
ATGAAGGTGCTCGGTATTGAATTGACACTTAAAAAATAG
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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