Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 928027..928681 Replicon chromosome
Accession NZ_AP022513
Organism Citrobacter portucalensis strain STN0717-72

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag JLF48_RS04485 Protein ID WP_200922871.1
Coordinates 928274..928681 (+) Length 136 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID -
Locus tag JLF48_RS04480 Protein ID WP_003825514.1
Coordinates 928027..928293 (+) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JLF48_RS04455 923182..924615 - 1434 WP_149334913.1 6-phospho-beta-glucosidase BglA -
JLF48_RS04460 924736..925464 - 729 WP_008785744.1 MurR/RpiR family transcriptional regulator -
JLF48_RS04465 925517..925828 + 312 WP_048225466.1 N(4)-acetylcytidine aminohydrolase -
JLF48_RS04470 925992..926654 + 663 WP_063940912.1 hemolysin III family protein -
JLF48_RS04475 926786..927769 - 984 WP_200921215.1 tRNA-modifying protein YgfZ -
JLF48_RS04480 928027..928293 + 267 WP_003825514.1 FAD assembly factor SdhE Antitoxin
JLF48_RS04485 928274..928681 + 408 WP_200922871.1 protein YgfX Toxin
JLF48_RS04490 928783..929304 - 522 WP_003825517.1 flavodoxin FldB -
JLF48_RS04495 929418..930314 + 897 WP_063940914.1 site-specific tyrosine recombinase XerD -
JLF48_RS04500 930338..931051 + 714 WP_003825520.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -
JLF48_RS04505 931057..932790 + 1734 WP_063940915.1 single-stranded-DNA-specific exonuclease RecJ -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(3-131)

Antitoxin

Flavinator of succinate dehydrogenase

(7-79)


Sequences

Toxin        


Download         Length: 136 a.a.        Molecular weight: 15852.74 Da        Isoelectric Point: 11.5783

>T35869 WP_200922871.1 NZ_AP022513:928274-928681 [Citrobacter portucalensis]
VVQWQSDLRVSWRAQWLSLLIHGLVAVFILLMPWPLSYTPLWLVLLSLVVFDSVRSQRRINACQGEIRLLMDGRLRRQGQ
EWSIVSAPWMVKTGMMLRLRSDAGKRQHLWLAADSMDDAEWRDLRRLMLQKAKQG

Download         Length: 408 bp

>T35869 NZ_AP022513:928274-928681 [Citrobacter portucalensis]
GTGGTCCAGTGGCAATCTGATTTACGCGTATCATGGCGCGCGCAGTGGCTTTCACTGCTAATTCATGGGCTGGTCGCGGT
GTTTATTTTATTGATGCCCTGGCCATTGAGCTACACCCCATTATGGCTGGTTTTGCTCTCTCTGGTGGTGTTCGATAGCG
TTCGCAGTCAGCGTCGAATCAACGCCTGTCAGGGTGAGATTCGGCTATTGATGGATGGCCGTCTGCGCAGGCAAGGGCAA
GAGTGGTCTATCGTTAGCGCCCCCTGGATGGTTAAAACAGGCATGATGCTGCGTTTGCGATCTGATGCCGGAAAACGTCA
ACATTTGTGGCTGGCAGCAGACAGTATGGATGATGCAGAGTGGCGGGATTTACGGCGGTTGATGCTGCAAAAGGCGAAGC
AAGGGTAA

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10615.14 Da        Isoelectric Point: 5.1700

>AT35869 WP_003825514.1 NZ_AP022513:928027-928293 [Citrobacter portucalensis]
MDINNKARIHWACRRGMRELDISIMPFFEHEYDSLSDEEKRIFIRLLECDDPDLFNWLMNHGKPADEQLEQMVRLIQTRN
RERGPVAI

Download         Length: 267 bp

>AT35869 NZ_AP022513:928027-928293 [Citrobacter portucalensis]
ATGGATATTAACAACAAAGCACGTATTCATTGGGCATGCCGCCGCGGTATGCGCGAGCTGGACATCTCGATCATGCCGTT
TTTCGAACATGAATATGACAGCTTAAGTGACGAAGAAAAACGTATCTTTATCCGTCTGCTAGAATGTGATGATCCAGATT
TATTTAACTGGTTGATGAATCATGGGAAACCAGCTGATGAGCAGCTGGAACAGATGGTGCGACTTATCCAGACACGGAAT
CGGGAACGTGGTCCAGTGGCAATCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References