Detailed information of TA system TA035851

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): /RES-TIGR02293
• Location: 1759268..1760181
• Replicon: chromosome
• Accession: NZ_AP022510
• Organism: Enterobacter hormaechei strain STN0717-64

Toxin (Protein)

• Gene name: -
• Uniprot ID: -
• Locus tag: JLF41_RS08380
• Protein ID: WP_032647883.1
• Coordinates: 1759268..1759741 (-)
• Length: 158 a.a.

Antitoxin (Protein)

• Gene name: -
• Uniprot ID: -
• Locus tag: JLF41_RS08385
• Protein ID: WP_023296216.1
• Coordinates: 1759738..1760181 (-)
• Length: 148 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
JLF41_RS08360	1755427..1756737	+	1311	WP_032647879.1	type I-F CRISPR-associated protein Csy1	-
JLF41_RS08365	1756734..1757669	+	936	WP_032647880.1	type I-F CRISPR-associated protein Csy2	-
JLF41_RS08370	1757683..1758681	+	999	WP_032647881.1	type I-F CRISPR-associated protein Csy3	-
JLF41_RS08375	1758691..1759245	+	555	WP_032647882.1	type I-F CRISPR-associated endoribonuclease Cas6/Csy4	-
JLF41_RS08380	1759268..1759741	-	474	WP_032647883.1	RES domain-containing protein	Toxin
JLF41_RS08385	1759738..1760181	-	444	WP_023296216.1	DUF2384 domain-containing protein	Antitoxin
JLF41_RS08390	1761279..1761497	-	219	WP_002211347.1	translation initiation factor IF-1	-
JLF41_RS08395	1761782..1762486	-	705	WP_032668747.1	leucyl/phenylalanyl-tRNA--protein transferase	-
JLF41_RS08400	1762532..1764253	-	1722	WP_032647885.1	cysteine/glutathione ABC transporter ATP-binding protein/permease CydC	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• RES domain (3-147)

Antitoxin

• Antitoxin Xre (15-147)

Sequences

Toxin

Protein

• Length: 158 a.a.
• Molecular weight: 17569.96 Da
• Isoelectric Point: 5.5555

>T35851 WP_032647883.1 NZ_AP022510:c1759741-1759268 [Enterobacter hormaechei]
MIFYRLVTGRFASEAWSGSGANQYGGRWNHKGHPAVYVSTSISLASLEILVHVRKDTVLNQYQLFSINIPDDQIDYLDKA
WLPEDWQENPAPVSTMDLGTGWLQANSALALILPSCIIPYENNAILNPLHPAFRKALNSVELLPFNFDTRLAEKTAP

Nucleotide

• Length: 474 bp

>T35851 NZ_AP022510:c1759741-1759268 [Enterobacter hormaechei]
ATGATTTTTTATCGTCTGGTGACAGGACGTTTTGCCAGCGAAGCGTGGAGTGGCAGTGGTGCAAACCAGTATGGCGGACG
CTGGAATCATAAAGGCCATCCTGCCGTGTATGTCTCCACCTCCATCTCGCTGGCTTCACTGGAAATTCTGGTGCATGTCA
GAAAAGACACCGTGCTGAACCAGTACCAGCTTTTCAGCATTAATATCCCGGATGATCAGATTGATTACCTGGATAAAGCG
TGGCTGCCCGAGGACTGGCAGGAAAATCCGGCGCCGGTATCAACGATGGATCTGGGTACCGGTTGGTTGCAGGCTAACAG
CGCTCTCGCACTCATCTTACCCTCCTGCATCATTCCCTATGAAAACAACGCCATACTTAATCCATTGCATCCGGCATTCC
GCAAAGCACTTAATTCTGTTGAGTTACTGCCTTTTAATTTTGATACCCGTCTCGCAGAAAAAACCGCACCCTGA

Antitoxin

Protein

• Length: 148 a.a.
• Molecular weight: 16512.81 Da
• Isoelectric Point: 6.4819

>AT35851 WP_023296216.1 NZ_AP022510:c1760181-1759738 [Enterobacter hormaechei]
MRTWVPAQRPADNTLWRYAGLPASRGMRLIEYLNQGLPVSVLDNIHEWTDMSKAEILRVTGINERNVARRKSTGRTLTPD
ESERVARFVRVLDAAVDYFGSKEEAWNWLQLPVRGLGNVAPVDLIATETGALEVTDLIGRLEHGVFA

Nucleotide

• Length: 444 bp

>AT35851 NZ_AP022510:c1760181-1759738 [Enterobacter hormaechei]
ATGAGAACATGGGTTCCTGCGCAAAGGCCGGCTGATAACACGCTGTGGCGCTACGCCGGTTTACCTGCAAGCAGAGGCAT
GCGGCTGATTGAATATCTCAATCAAGGATTACCCGTCAGCGTCCTCGACAATATTCACGAGTGGACGGACATGTCGAAAG
CGGAGATTTTACGCGTCACGGGAATTAACGAGCGTAACGTTGCCCGCCGCAAAAGTACGGGCCGGACGCTGACGCCCGAC
GAGAGCGAACGTGTGGCGCGTTTCGTTCGGGTACTGGATGCGGCCGTCGATTATTTCGGCAGTAAAGAAGAGGCATGGAA
CTGGTTGCAGTTACCGGTACGTGGGCTTGGCAATGTTGCGCCTGTCGATCTGATTGCCACGGAAACCGGTGCGCTGGAAG
TTACCGATTTGATTGGTCGGCTGGAGCACGGAGTGTTCGCATGA