Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumAB/COG3657-dnstrm_HI1420
Location 294574..295170 Replicon chromosome
Accession NZ_AP022510
Organism Enterobacter hormaechei strain STN0717-64

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag JLF41_RS01405 Protein ID WP_023295756.1
Coordinates 294868..295170 (-) Length 101 a.a.

Antitoxin (Protein)


Gene name PumB Uniprot ID A0A927HL08
Locus tag JLF41_RS01400 Protein ID WP_023295755.1
Coordinates 294574..294861 (-) Length 96 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JLF41_RS01395 292946..294577 + 1632 WP_003860350.1 Na/Pi cotransporter family protein -
JLF41_RS01400 294574..294861 - 288 WP_023295755.1 putative addiction module antidote protein Antitoxin
JLF41_RS01405 294868..295170 - 303 WP_023295756.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
JLF41_RS01410 295368..296240 + 873 WP_032646867.1 23S rRNA pseudouridine(2604) synthase RluF -
JLF41_RS01415 296241..296513 - 273 WP_017382612.1 DUF3811 domain-containing protein -
JLF41_RS01420 296564..297508 - 945 WP_032646868.1 ketopantoate/pantoate/pantothenate transporter PanS -
JLF41_RS01425 297602..298951 - 1350 WP_006810501.1 lysine-sensitive aspartokinase 3 -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(3-93)

Antitoxin

Uncharacterized protein HI1420

(3-90)


Sequences

Toxin        


Download         Length: 101 a.a.        Molecular weight: 11441.24 Da        Isoelectric Point: 10.1042

>T35847 WP_023295756.1 NZ_AP022510:c295170-294868 [Enterobacter hormaechei]
MKEIVQTESFRRWEQNLKDRRAKTIIASRLFRLANGLAGDIRPVGEGISELRIHFGPGYRIYFKDQGNCIIVLLCGGDKS
SQARDILMAKMLSNVSQWQE

Download         Length: 303 bp

>T35847 NZ_AP022510:c295170-294868 [Enterobacter hormaechei]
ATGAAGGAGATCGTTCAGACAGAATCCTTCCGACGCTGGGAGCAAAATTTAAAGGACAGGCGGGCAAAGACGATTATCGC
CTCCCGCCTCTTTAGGCTGGCAAATGGCTTAGCGGGCGACATTAGACCTGTGGGAGAAGGTATCAGTGAACTGAGGATTC
ACTTTGGCCCGGGCTACAGGATCTATTTTAAGGACCAGGGCAATTGCATCATCGTGCTGTTATGTGGTGGTGACAAAAGC
AGCCAGGCCAGAGACATACTTATGGCAAAAATGCTGAGCAATGTATCCCAATGGCAGGAGTGA

Antitoxin


Download         Length: 96 a.a.        Molecular weight: 10101.59 Da        Isoelectric Point: 5.7807

>AT35847 WP_023295755.1 NZ_AP022510:c294861-294574 [Enterobacter hormaechei]
MHKLTPYDPANALLDDEEIAVFMADALETGDSAYIAKALGVIARAKGMSTISQQTGLSREQLYRSFSDKGNPTLKTTLAV
MKALGLGLTIKPSGD

Download         Length: 288 bp

>AT35847 NZ_AP022510:c294861-294574 [Enterobacter hormaechei]
ATGCATAAATTAACACCCTACGATCCAGCCAACGCACTGCTGGATGACGAGGAAATCGCTGTGTTTATGGCTGATGCATT
AGAGACGGGTGACTCAGCGTACATTGCTAAAGCGCTGGGCGTCATCGCCCGAGCGAAAGGGATGTCGACCATTTCCCAGC
AAACGGGCCTGTCACGAGAACAACTGTATCGATCATTCAGTGATAAGGGGAACCCAACGCTCAAAACCACGCTGGCGGTC
ATGAAAGCATTGGGCCTTGGGTTAACAATCAAACCCTCTGGGGATTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References