Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | vapBC/LOTUS_5_Limkain_b1(toxin) |
Location | 4542069..4542685 | Replicon | chromosome |
Accession | NZ_AP022508 | ||
Organism | Enterobacter bugandensis strain STN0717-56 |
Toxin (Protein)
Gene name | vapC | Uniprot ID | - |
Locus tag | JLD64_RS21530 | Protein ID | WP_193031919.1 |
Coordinates | 4542069..4542440 (-) | Length | 124 a.a. |
Antitoxin (Protein)
Gene name | vapB | Uniprot ID | A0A6G4MTK3 |
Locus tag | JLD64_RS21535 | Protein ID | WP_015569912.1 |
Coordinates | 4542443..4542685 (-) | Length | 81 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
JLD64_RS21515 | 4539569..4540471 | + | 903 | WP_003861960.1 | formate dehydrogenase subunit beta | - |
JLD64_RS21520 | 4540468..4541103 | + | 636 | WP_015569914.1 | formate dehydrogenase cytochrome b556 subunit | - |
JLD64_RS21525 | 4541100..4542029 | + | 930 | WP_028014872.1 | formate dehydrogenase accessory protein FdhE | - |
JLD64_RS21530 | 4542069..4542440 | - | 372 | WP_193031919.1 | PIN domain-containing protein | Toxin |
JLD64_RS21535 | 4542443..4542685 | - | 243 | WP_015569912.1 | ribbon-helix-helix domain-containing protein | Antitoxin |
JLD64_RS21540 | 4542884..4543804 | + | 921 | WP_199887042.1 | alpha/beta hydrolase | - |
JLD64_RS21545 | 4543813..4544754 | - | 942 | WP_047366783.1 | fatty acid biosynthesis protein FabY | - |
JLD64_RS21550 | 4544799..4545236 | - | 438 | WP_008501836.1 | D-tyrosyl-tRNA(Tyr) deacylase | - |
JLD64_RS21555 | 4545233..4546114 | - | 882 | WP_045260235.1 | virulence factor BrkB family protein | - |
JLD64_RS21560 | 4546108..4546707 | - | 600 | WP_045260234.1 | glucose-1-phosphatase | - |
JLD64_RS21565 | 4546795..4547265 | - | 471 | WP_028014878.1 | hypothetical protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 124 a.a. Molecular weight: 13706.95 Da Isoelectric Point: 7.4764
>T35846 WP_193031919.1 NZ_AP022508:c4542440-4542069 [Enterobacter bugandensis]
MKHMAVFDTNILIDLFNNRVEAADAIEHTASHRAISLITWMEVMVGARRHGHEAKTAAVMGAFEIIDVSRDIAERSVLLR
EKHGMKLPDAIILATAQSRKCPLISRNTKVFAGIDEVLTPYQV
MKHMAVFDTNILIDLFNNRVEAADAIEHTASHRAISLITWMEVMVGARRHGHEAKTAAVMGAFEIIDVSRDIAERSVLLR
EKHGMKLPDAIILATAQSRKCPLISRNTKVFAGIDEVLTPYQV
Download Length: 372 bp
>T35846 NZ_AP022508:c4542440-4542069 [Enterobacter bugandensis]
ATGAAGCACATGGCAGTGTTTGATACCAATATTCTCATTGATCTCTTCAACAACCGTGTTGAAGCTGCGGATGCGATTGA
GCATACCGCGTCGCATCGTGCCATCAGCTTAATTACCTGGATGGAAGTGATGGTGGGCGCTCGCAGGCATGGTCATGAAG
CGAAAACGGCAGCCGTGATGGGCGCTTTTGAAATTATTGATGTGTCTCGGGATATCGCGGAAAGAAGCGTTTTACTACGT
GAGAAGCATGGAATGAAACTGCCTGATGCTATCATCCTGGCTACAGCGCAAAGCAGAAAATGTCCGTTGATTTCTCGCAA
CACGAAAGTTTTTGCGGGTATTGACGAGGTCCTTACGCCTTACCAGGTGTAG
ATGAAGCACATGGCAGTGTTTGATACCAATATTCTCATTGATCTCTTCAACAACCGTGTTGAAGCTGCGGATGCGATTGA
GCATACCGCGTCGCATCGTGCCATCAGCTTAATTACCTGGATGGAAGTGATGGTGGGCGCTCGCAGGCATGGTCATGAAG
CGAAAACGGCAGCCGTGATGGGCGCTTTTGAAATTATTGATGTGTCTCGGGATATCGCGGAAAGAAGCGTTTTACTACGT
GAGAAGCATGGAATGAAACTGCCTGATGCTATCATCCTGGCTACAGCGCAAAGCAGAAAATGTCCGTTGATTTCTCGCAA
CACGAAAGTTTTTGCGGGTATTGACGAGGTCCTTACGCCTTACCAGGTGTAG
Antitoxin
Download Length: 81 a.a. Molecular weight: 9440.72 Da Isoelectric Point: 4.4076
>AT35846 WP_015569912.1 NZ_AP022508:c4542685-4542443 [Enterobacter bugandensis]
MSVLAELDMGRILIDLSDDVIQRLDNLKQLRNQPRAELLREAIELYLDQQSSSVIRNALGLWGDRKEDGLEYERKLREEW
MSVLAELDMGRILIDLSDDVIQRLDNLKQLRNQPRAELLREAIELYLDQQSSSVIRNALGLWGDRKEDGLEYERKLREEW
Download Length: 243 bp
>AT35846 NZ_AP022508:c4542685-4542443 [Enterobacter bugandensis]
ATGAGCGTTTTGGCGGAACTTGATATGGGCAGAATACTTATCGATTTGTCTGATGACGTGATTCAACGTTTGGATAACCT
CAAGCAATTGCGAAATCAACCACGTGCCGAACTGCTTCGCGAAGCGATAGAGCTGTATCTCGACCAGCAGAGTTCTTCTG
TTATCCGAAATGCGCTTGGTCTGTGGGGAGACAGAAAAGAGGACGGGCTTGAGTATGAACGCAAGCTGCGTGAGGAGTGG
TAA
ATGAGCGTTTTGGCGGAACTTGATATGGGCAGAATACTTATCGATTTGTCTGATGACGTGATTCAACGTTTGGATAACCT
CAAGCAATTGCGAAATCAACCACGTGCCGAACTGCTTCGCGAAGCGATAGAGCTGTATCTCGACCAGCAGAGTTCTTCTG
TTATCCGAAATGCGCTTGGTCTGTGGGGAGACAGAAAAGAGGACGGGCTTGAGTATGAACGCAAGCTGCGTGAGGAGTGG
TAA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|