Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 3933672..3934329 Replicon chromosome
Accession NZ_AP022498
Organism Enterobacter kobei strain STN0717-53

Toxin (Protein)


Gene name cptA Uniprot ID A0A2W0G6Z0
Locus tag JLH17_RS18930 Protein ID WP_014885136.1
Coordinates 3933672..3934082 (-) Length 137 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID V3PWU7
Locus tag JLH17_RS18935 Protein ID WP_010435322.1
Coordinates 3934063..3934329 (-) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JLH17_RS18910 3929666..3931399 - 1734 WP_032635612.1 single-stranded-DNA-specific exonuclease RecJ -
JLH17_RS18915 3931405..3932118 - 714 WP_014885133.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -
JLH17_RS18920 3932147..3933043 - 897 WP_014885134.1 site-specific tyrosine recombinase XerD -
JLH17_RS18925 3933145..3933666 + 522 WP_014885135.1 flavodoxin FldB -
JLH17_RS18930 3933672..3934082 - 411 WP_014885136.1 protein YgfX Toxin
JLH17_RS18935 3934063..3934329 - 267 WP_010435322.1 FAD assembly factor SdhE Antitoxin
JLH17_RS18940 3934624..3935604 + 981 WP_045269629.1 tRNA-modifying protein YgfZ -
JLH17_RS18945 3935689..3936348 - 660 WP_023331242.1 hemolysin III family protein -
JLH17_RS18950 3936614..3937345 + 732 WP_014885139.1 MurR/RpiR family transcriptional regulator -
JLH17_RS18955 3937462..3938895 + 1434 WP_045269628.1 6-phospho-beta-glucosidase BglA -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(3-132)

Antitoxin

Flavinator of succinate dehydrogenase

(7-79)


Sequences

Toxin        


Download         Length: 137 a.a.        Molecular weight: 16135.04 Da        Isoelectric Point: 10.7510

>T35828 WP_014885136.1 NZ_AP022498:c3934082-3933672 [Enterobacter kobei]
VVLWQSDLRVSWRSQWMSLMLHGLVAAIVLLMPWPLSYTPLWLLLLSFVVFDSVRSQRRINARQGEIKLLMDSRLRWQGK
EWDILGMPWMLNSGMMLRLRNVDGGRCQHLWLAADSMDASEWRDLRRMLLQQPTQE

Download         Length: 411 bp

>T35828 NZ_AP022498:c3934082-3933672 [Enterobacter kobei]
GTGGTCCTGTGGCAATCTGATCTTCGCGTCTCGTGGCGCTCGCAGTGGATGTCGTTAATGCTCCACGGCCTGGTTGCGGC
CATCGTGTTACTCATGCCATGGCCCCTGAGCTATACACCGCTGTGGCTGCTATTACTTTCGTTTGTCGTTTTTGACAGCG
TACGCAGCCAGCGTCGCATTAATGCTCGTCAGGGTGAGATCAAGTTACTGATGGATTCCCGCCTGCGCTGGCAGGGAAAA
GAGTGGGATATTCTGGGTATGCCATGGATGCTCAACTCCGGCATGATGTTACGGTTACGCAATGTGGACGGCGGGCGTTG
CCAGCACCTGTGGCTGGCGGCTGACAGTATGGATGCTTCAGAATGGCGAGATCTGCGCCGGATGTTGTTGCAACAGCCGA
CGCAGGAGTAA

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10555.02 Da        Isoelectric Point: 5.1340

>AT35828 WP_010435322.1 NZ_AP022498:c3934329-3934063 [Enterobacter kobei]
MDINNKARIHWACRRGMRELDISIMPFFEYEYDSLSDDDKRLFVRLLESDDPDLFNWLMNHGKPADTELQRMVQLIQTRN
RERGPVAI

Download         Length: 267 bp

>AT35828 NZ_AP022498:c3934329-3934063 [Enterobacter kobei]
ATGGATATTAACAACAAGGCCCGTATTCACTGGGCATGCCGTCGCGGCATGCGTGAACTTGATATTTCCATCATGCCTTT
CTTCGAATATGAGTATGACAGCTTAAGCGATGATGATAAGCGGCTGTTTGTTCGCCTGCTTGAGTCTGACGATCCAGATT
TATTCAACTGGCTGATGAACCACGGCAAACCCGCCGACACCGAGTTGCAACGGATGGTGCAATTAATTCAAACACGGAAT
CGGGAACGTGGTCCTGTGGCAATCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2W0G6Z0

Antitoxin

Source ID Structure
AlphaFold DB V3PWU7

References