Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) chpSB/PRK09812-ChpS
Location 484674..485269 Replicon chromosome
Accession NZ_AP022498
Organism Enterobacter kobei strain STN0717-53

Toxin (Protein)


Gene name chpB Uniprot ID A0A7I7DTC3
Locus tag JLH17_RS02310 Protein ID WP_045268863.1
Coordinates 484919..485269 (+) Length 117 a.a.

Antitoxin (Protein)


Gene name chpS Uniprot ID A0A7I7DTG4
Locus tag JLH17_RS02305 Protein ID WP_045268862.1
Coordinates 484674..484925 (+) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JLH17_RS02295 480341..484117 + 3777 WP_200928149.1 translocation/assembly module TamB -
JLH17_RS02300 484120..484464 + 345 WP_014882267.1 gamma-glutamylcyclotransferase -
JLH17_RS02305 484674..484925 + 252 WP_045268862.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein Antitoxin
JLH17_RS02310 484919..485269 + 351 WP_045268863.1 type II toxin-antitoxin system ChpB family toxin Toxin
JLH17_RS02315 485347..485877 - 531 WP_008501423.1 inorganic diphosphatase -
JLH17_RS02320 486187..487143 + 957 WP_014882271.1 galactofuranose ABC transporter substrate-binding protein YtfQ -
JLH17_RS02325 487246..488748 + 1503 WP_045134407.1 sugar ABC transporter ATP-binding protein -
JLH17_RS02330 488759..489784 + 1026 WP_014882273.1 ABC transporter permease -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(8-114)

Antitoxin

SpoVT-AbrB domain

(6-47)


Sequences

Toxin        


Download         Length: 117 a.a.        Molecular weight: 12340.31 Da        Isoelectric Point: 6.9488

>T35815 WP_045268863.1 NZ_AP022498:484919-485269 [Enterobacter kobei]
MVKRPCFERGDIVLVGFDPANGHEQKGAGRPALVLSVSAFNQLGMTLVAPVTQGGNFARYAGFSVPLSCEEGNIQGVILV
NQIRMMDLGARLAKRIGVASDETVDDALLRLQAILS

Download         Length: 351 bp

>T35815 NZ_AP022498:484919-485269 [Enterobacter kobei]
ATGGTGAAGCGACCTTGTTTTGAACGAGGTGATATCGTTCTCGTCGGCTTCGATCCTGCAAATGGTCATGAACAAAAGGG
CGCAGGCAGGCCCGCTTTAGTGCTATCCGTTAGCGCGTTCAACCAGCTGGGAATGACGCTGGTTGCGCCTGTTACACAGG
GAGGAAATTTTGCCCGCTATGCGGGTTTCAGTGTGCCGCTGTCTTGTGAAGAAGGGAATATTCAGGGCGTCATTCTGGTA
AACCAAATCCGAATGATGGATTTGGGCGCGCGTCTGGCAAAACGAATAGGCGTGGCATCAGATGAAACCGTAGACGATGC
GCTTTTAAGGCTACAGGCCATCCTGAGTTAA

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9069.43 Da        Isoelectric Point: 4.4368

>AT35815 WP_045268862.1 NZ_AP022498:484674-484925 [Enterobacter kobei]
MRITIKKWGNSAGMVIPGVVMKELGLKPGQSMEAQVTNNHLVLTPVSKQYSLEELLAQCDMSAPEINEQDVWGTSGPVGD
EVW

Download         Length: 252 bp

>AT35815 NZ_AP022498:484674-484925 [Enterobacter kobei]
ATGCGTATAACCATTAAGAAATGGGGAAACAGTGCCGGTATGGTCATTCCTGGCGTAGTAATGAAAGAACTTGGCCTAAA
ACCAGGTCAGAGTATGGAGGCTCAGGTGACAAATAATCATTTAGTGCTCACACCGGTGAGTAAACAGTACTCGCTTGAAG
AGTTGTTGGCGCAGTGTGATATGTCAGCCCCGGAAATTAACGAACAAGACGTATGGGGTACGTCAGGTCCCGTAGGTGAC
GAAGTATGGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A7I7DTC3

Antitoxin

Source ID Structure
AlphaFold DB A0A7I7DTG4

References